deferoxamine has been researched along with Cancer of Ovary in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human ovarian cancer cells and normal human ovarian epithelial cell line IOSE-80 were cultured and administrated with deferoxamine (DFO) or ferric ammonium citrate (FAC)." | 1.62 | Significance of glutathione peroxidase 4 and intracellular iron level in ovarian cancer cells-"utilization" of ferroptosis mechanism. ( Chao, H; Li, D; Zhang, M, 2021) |
| "DFO and DTPA were cytotoxic to ovarian cancer cells in a dose- and time-dependent manner." | 1.33 | Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma. ( Brard, L; Granai, CO; Swamy, N, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, D | 1 |
| Zhang, M | 1 |
| Chao, H | 1 |
| Pourgholami, MH | 1 |
| Cai, ZY | 1 |
| Badar, S | 1 |
| Wangoo, K | 1 |
| Poruchynsky, MS | 1 |
| Morris, DL | 1 |
| Yeung, HY | 1 |
| Lai, KP | 1 |
| Chan, HY | 1 |
| Mak, NK | 1 |
| Wagner, GF | 1 |
| Wong, CK | 1 |
| Brard, L | 1 |
| Granai, CO | 1 |
| Swamy, N | 1 |
4 other studies available for deferoxamine and Cancer of Ovary
| Article | Year |
|---|---|
Significance of glutathione peroxidase 4 and intracellular iron level in ovarian cancer cells-"utilization" of ferroptosis mechanism.
Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Deferoxamine; Female; Ferric Compounds; Ferroptos | 2021 |
Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole.
Topics: Albendazole; Angiogenesis Inhibitors; Animals; Cell Hypoxia; Cell Line, Tumor; Deferoxamine; Dose-Re | 2010 |
Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Deferoxamine; Female; Ferric Compounds; Ferricyanides; Glycopro | 2005 |
Iron chelators deferoxamine and diethylenetriamine pentaacetic acid induce apoptosis in ovarian carcinoma.
Topics: Animals; Apoptosis; Caspases; Cell Growth Processes; Cell Line, Tumor; Deferoxamine; Enzyme Activati | 2006 |