deferoxamine has been researched along with Cancer of Mouth in 9 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "BQ chewing is the major risk factor of oral cancer in India, Taiwan, South Africa and numerous other countries." | 1.31 | Prevention of the areca nut extract-induced unscheduled DNA synthesis of gingival keratinocytes by vitamin C and thiol compounds. ( Chang, MC; Hahn, LJ; Ho, YS; Jeng, JH; Kok, SH; Lee, JJ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamamoto, M | 1 |
| Fujita, H | 1 |
| Katase, N | 1 |
| Inoue, K | 1 |
| Nagatsuka, H | 1 |
| Utsumi, K | 1 |
| Sasaki, J | 1 |
| Ohuchi, H | 1 |
| Uekusa, M | 1 |
| Omura, K | 1 |
| Nakajima, Y | 1 |
| Hasegawa, S | 1 |
| Harada, H | 1 |
| Morita, KI | 1 |
| Tsuda, H | 1 |
| Hershkovich, O | 1 |
| Oliva, J | 1 |
| Nagler, RM | 1 |
| Lee, SK | 8 |
| Lee, JJ | 2 |
| Lee, HJ | 3 |
| Lee, J | 4 |
| Jeon, BH | 2 |
| Jun, CD | 3 |
| Kim, EC | 4 |
| Jang, HJ | 1 |
| Nakagawa, H | 1 |
| Matsumiya, T | 1 |
| Sakaki, H | 1 |
| Imaizumi, T | 1 |
| Kubota, K | 1 |
| Kusumi, A | 1 |
| Kobayashi, W | 1 |
| Kimura, H | 1 |
| Min, SK | 1 |
| Won, DH | 1 |
| Lee, YM | 1 |
| Lim, HD | 1 |
| Lee, W | 1 |
| Pae, HO | 1 |
| Chung, HT | 1 |
| Chang, MC | 1 |
| Ho, YS | 1 |
| Kok, SH | 1 |
| Hahn, LJ | 1 |
| Jeng, JH | 1 |
9 other studies available for deferoxamine and Cancer of Mouth
| Article | Year |
|---|---|
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
Topics: Amino Acid Chloromethyl Ketones; Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, S | 2013 |
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.
Topics: Amino Acids, Neutral; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Deferoxamine; Drug Co | 2010 |
Lethal synergistic effect of cigarette smoke and saliva in an in vitro model: does saliva have a role in the development of oral cancer?
Topics: Adult; Antioxidants; Cell Survival; Deferoxamine; Female; Free Radicals; Glutathione; Humans; In Vit | 2004 |
Iron chelator-induced growth arrest and cytochrome c-dependent apoptosis in immortalized and malignant oral keratinocytes.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases | 2006 |
p38 and ERK MAP kinase mediates iron chelator-induced apoptosis and -suppressed differentiation of immortalized and malignant human oral keratinocytes.
Topics: Apoptosis; Caspase 3; Caspase 8; Caspases; Cell Differentiation; Cell Proliferation; Cytochromes c; | 2006 |
Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cycloheximide; Deferoxamine; Enzyme Inhibitors; Enzyme-L | 2007 |
Differential regulation of iron chelator-induced IL-8 synthesis via MAP kinase and NF-kappaB in immortalized and malignant oral keratinocytes.
Topics: Cells, Cultured; Deferoxamine; Humans; Interleukin-8; Iron Chelating Agents; Keratinocytes; Mitogen- | 2007 |
Iron chelator differentially activates macrophage inflammatory protein-3alpha/CCL20 in immortalized and malignant human oral keratinocytes.
Topics: Carcinoma, Squamous Cell; Chemokine CCL20; Deferoxamine; Enzyme-Linked Immunosorbent Assay; Female; | 2008 |
Prevention of the areca nut extract-induced unscheduled DNA synthesis of gingival keratinocytes by vitamin C and thiol compounds.
Topics: Antioxidants; Areca; Ascorbic Acid; Cells, Cultured; Chelating Agents; Deferoxamine; DNA; Gingiva; H | 2002 |