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deferoxamine and Cancer of Liver

deferoxamine has been researched along with Cancer of Liver in 43 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"The multikinase inhibitor sorafenib is currently the treatment of reference for advanced hepatocellular carcinoma (HCC)."7.79Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib. ( Barbare, JC; Chauffert, B; Ezzoukhry, Z; Galmiche, A; Godin, C; Louandre, C; Mazière, JC, 2013)
"Inhibition of human hepatocellular carcinoma (PLC/PRF/5 and Hep3B) or hepatoblastoma (Hep G2) cell lines by inclusion of deferoxamine mesylate (desferrioxamine) (DFX) in the culture medium was evaluated."7.68Inhibition of human hepatocellular carcinoma and hepatoblastoma cell lines by deferoxamine. ( Kim, CM; Tabor, E, 1991)
"However, hepatocellular carcinoma (HCC) shows resistance to the anti-proliferative effect of IFN-gamma, due mainly to down-regulation of IFN-gamma receptor chain 2 (IFN-gammaR2), even though IFN-gamma receptor chain 1 (IFN-gammaR1), the domain that includes the binding site of IFN-gamma, is stably expressed."5.34Deferoxamine enhances anti-proliferative effect of interferon-gamma against hepatocellular carcinoma cells. ( Kubota, K; Okada, T; Sawada, T, 2007)
"Porphyria was induced in vivo in mice using 3,5-diethoxycarbonyl-1,4-dihydrocollidine or in vitro by exposing human liver Huh7 cells and keratinocytes, or their lysates, to protoporphyrin-IX, other porphyrins, or to δ-aminolevulinic acid plus deferoxamine."3.91Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells. ( Basrur, V; Carter, EL; Herrmann, H; Lehnert, N; Maitra, D; Nesvizhskii, AI; Omary, MB; Osawa, Y; Ragsdale, SW; Richardson, R; Rittié, L; Wolf, MW; Zhang, H, 2019)
"The multikinase inhibitor sorafenib is currently the treatment of reference for advanced hepatocellular carcinoma (HCC)."3.79Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib. ( Barbare, JC; Chauffert, B; Ezzoukhry, Z; Galmiche, A; Godin, C; Louandre, C; Mazière, JC, 2013)
"Hepatic non-transferrin-bound Fe (NTBI) flux and its regulation were characterized by measuring the uptake of Fe from [59Fe]/nitrilotriacetate (NTA) complexes in control and Fe-loaded cultures of human hepatocellular carcinoma cells (HepG2)."3.69Modulation by iron loading and chelation of the uptake of non-transferrin-bound iron by human liver cells. ( Olivieri, NF; Parkes, JG; Randell, EW; Templeton, DM, 1995)
"Inhibition of human hepatocellular carcinoma (PLC/PRF/5 and Hep3B) or hepatoblastoma (Hep G2) cell lines by inclusion of deferoxamine mesylate (desferrioxamine) (DFX) in the culture medium was evaluated."3.68Inhibition of human hepatocellular carcinoma and hepatoblastoma cell lines by deferoxamine. ( Kim, CM; Tabor, E, 1991)
"Deferoxamine-treated animals had reduced total bilirubin, gamma-glutamyl transferase and ammonia levels as well as hepatocyte necrosis and oxidative injury."1.36Iron chelation for amelioration of liver ischemia-reperfusion injury. ( Arkadopoulos, N; Economou, E; Kalimeris, K; Kostopanagiotou, G; Kouskouni, E; Nastos, C; Pafiti, A; Smyrniotis, V; Theodoraki, K, 2010)
"However, hepatocellular carcinoma (HCC) shows resistance to the anti-proliferative effect of IFN-gamma, due mainly to down-regulation of IFN-gamma receptor chain 2 (IFN-gammaR2), even though IFN-gamma receptor chain 1 (IFN-gammaR1), the domain that includes the binding site of IFN-gamma, is stably expressed."1.34Deferoxamine enhances anti-proliferative effect of interferon-gamma against hepatocellular carcinoma cells. ( Kubota, K; Okada, T; Sawada, T, 2007)
"Deferoxamine was added to the cultures to achieve final concentrations of 200-800 microg/ml, corresponding to in vivo infusion rates of 15-60 mg/kg/h."1.31Deferoxamine toxicity in hepatoma and primary rat cortical brain cultures. ( Christensen, DW; Kirby, MA; Kisling, R; Thompson, J, 2001)
"The recovery from iron overload is hampered by the limited number of pathways and therapeutic agents available for the augmentation of iron secretion/excretion."1.31Acquisition, storage and release of iron by cultured human hepatoma cells. ( Hirsh, M; Iancu, TC; Konijn, AM, 2002)
" In contrast to arachidonic acid, oleic acid was not toxic to the Hep G2-MV2E1-9 cells."1.30Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1. ( Cederbaum, AI; Chen, Q; Galleano, M, 1997)
"Using Hep 3B cells as the hepatoma cell lines, DNA synthesis was measured by [3H] thymidine incorporation, and the cell cycle analysis was performed by flow cytometry including bivariate DNA/BrdU analysis."1.29The mechanism of antiproliferative effect of desferrioxamine on human hepatoma cell lines. ( Kang, JK; Kim, DY; Kim, WH; Kwon, OH; Park, S, 1994)
" Survival fractions were measured by quantitative colorimetric assay (MTT assay) and dose-response curves were plotted."1.29Effect of anticancer drugs and desferrioxamine in combination with radiation on hepatoma cell lines. ( Choi, HJ; Chon, CY; Kang, JK; Kim, WH; Moon, YM; Park, IS, 1993)
"Cells from a rat hepatoma grown in culture were found to activate methyldopa to intermediates which are bound irreversibly to cellular proteins."1.26Methyldopa binding to cells in culture. ( Dybing, E, 1977)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19904 (9.30)18.7374
1990's18 (41.86)18.2507
2000's10 (23.26)29.6817
2010's10 (23.26)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Kim, KM1
Cho, SS1
Ki, SH1
Maitra, D1
Carter, EL1
Richardson, R1
Rittié, L1
Basrur, V1
Zhang, H1
Nesvizhskii, AI1
Osawa, Y1
Wolf, MW1
Ragsdale, SW1
Lehnert, N1
Herrmann, H1
Omary, MB1
Louandre, C1
Ezzoukhry, Z1
Godin, C1
Barbare, JC1
Mazière, JC1
Chauffert, B1
Galmiche, A1
Minero, VG1
Khadjavi, A1
Costelli, P1
Baccino, FM1
Bonelli, G1
Befani, C1
Mylonis, I1
Gkotinakou, IM1
Georgoulias, P1
Hu, CJ1
Simos, G1
Liakos, P1
Salis, O1
Bedir, A1
Kilinc, V1
Alacam, H1
Gulten, S1
Okuyucu, A1
Dessì, C1
Leoni, G1
Moi, P1
Danjou, F1
Follesa, I1
Foschini, ML1
Morittu, M1
Zappu, A1
Defraia, E1
Bina, P1
Cunico, A1
Civolani, A1
Podda, RA1
Origa, R1
Hernandez, R1
Sun, H1
England, CG1
Valdovinos, HF1
Ehlerding, EB1
Barnhart, TE1
Yang, Y1
Cai, W1
Hou, WH1
Rossi, L1
Shan, Y1
Zheng, JY1
Lambrecht, RW1
Bonkovsky, HL1
Fragatou, S1
Tsourveloudis, I1
Manesis, G1
Arkadopoulos, N1
Nastos, C1
Kalimeris, K1
Economou, E1
Theodoraki, K1
Kouskouni, E1
Pafiti, A1
Kostopanagiotou, G1
Smyrniotis, V1
Yamasaki, T1
Terai, S1
Sakaida, I1
Chua, AC2
Ingram, HA1
Raymond, KN1
Baker, E2
Vengellur, A1
Phillips, JM1
Hogenesch, JB1
LaPres, JJ1
Okada, T1
Sawada, T1
Kubota, K1
Alvarez, MG1
Lacelli, MS1
Rivarola, V1
Batlle, A1
Fukuda, H1
Sommani, P1
Yamashita, K1
Miyoshi, T1
Tsunemine, H1
Kodaki, T1
Mori, H1
Hirota, K1
Arai, T1
Sasada, M1
Makino, K1
Cohen, A1
Witzleben, C1
Schwartz, E1
Propper, R1
Nathan, D1
Nishikawa, Y1
Carr, BI1
Wang, M1
Kar, S1
Finn, F1
Dowd, P1
Zheng, ZB1
Kerns, J1
Naganathan, S1
Gleadle, JM1
Ebert, BL1
Firth, JD1
Ratcliffe, PJ1
Bertrand, E1
Fromont-Racine, M1
Pictet, R1
Grange, T1
Parkes, JG1
Randell, EW1
Olivieri, NF1
Templeton, DM1
Kountouras, J1
Boura, P1
Karolides, A1
Zaharioudaki, E1
Tsapas, G1
Kim, DY1
Kim, WH2
Kang, JK2
Park, S1
Kwon, OH1
Wang, GL1
Semenza, GL2
Chon, CY1
Moon, YM1
Park, IS1
Choi, HJ1
Glickstein, H1
Breuer, W1
Loyevsky, M1
Konijn, AM2
Shanzer, A2
Cabantchik, ZI2
Kling, PJ1
Dragsten, PR1
Roberts, RA1
Dos Santos, B1
Brooks, DJ1
Hedlund, BE1
Taetle, R1
Chen, Q1
Galleano, M1
Cederbaum, AI1
Chiou, TJ1
Chou, YT1
Tzeng, WF1
Agani, F1
Christensen, DW1
Kisling, R1
Thompson, J1
Kirby, MA1
Minchenko, A1
Leshchinsky, I1
Opentanova, I1
Sang, N1
Srinivas, V1
Armstead, V1
Caro, J1
Kicic, A1
Hirsh, M1
Iancu, TC1
Dybing, E1
Hann, HW2
Stahlhut, MW2
Rubin, R1
Maddrey, WC1
Lytton, SD1
Mester, B1
Libman, J1
Rogers, JT1
Bridges, KR1
Durmowicz, GP1
Glass, J1
Auron, PE1
Munro, HN1
Tabor, E1
Kim, CM1
Hann, CL1
Darnis, F1
Mossé, A1
Breauté, C1
Delorme, ML1

Reviews

3 reviews available for deferoxamine and Cancer of Liver

ArticleYear
Emerging roles of ferroptosis in liver pathophysiology.
    Archives of pharmacal research, 2020, Volume: 43, Issue:10

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Carcinoma, Hepatocellular; Cycloheximide; Cyclohexyla

2020
Treatment of iron overload.
    Seminars in liver disease, 1984, Volume: 4, Issue:3

    Topics: Bloodletting; Carcinoma, Hepatocellular; Deferoxamine; Hemochromatosis; Humans; Liver; Liver Cirrhos

1984
Clinical removal of iron.
    Annual review of medicine, 1982, Volume: 33

    Topics: Adult; Anemia, Sideroblastic; Bloodletting; Carcinoma, Hepatocellular; Deferoxamine; Diet; Erythropo

1982

Trials

3 trials available for deferoxamine and Cancer of Liver

ArticleYear
Deferoxamine for advanced hepatocellular carcinoma.
    The New England journal of medicine, 2011, Aug-11, Volume: 365, Issue:6

    Topics: Adult; Aged; Biomarkers, Tumor; Carcinoma, Hepatocellular; Deferoxamine; Female; Humans; Liver Neopl

2011
Recombinant a2 interferon (a-IFN) with chemo-hormonal therapy in patients with hepatocellular carcinoma (HCC).
    Hepato-gastroenterology, 1995, Volume: 42, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Carcinoma, Hepatocellular; Combined M

1995
Iron deprivation increases erythropoietin production in vitro, in normal subjects and patients with malignancy.
    British journal of haematology, 1996, Volume: 95, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Blood Cell Count; Carcinoma, Hepatocellular; Cell Hypoxia; Deferoxami

1996

Other Studies

37 other studies available for deferoxamine and Cancer of Liver

ArticleYear
Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells.
    Cellular and molecular gastroenterology and hepatology, 2019, Volume: 8, Issue:4

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cell Line; Deferoxamine; Heme; Hepatocytes;

2019
Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib.
    International journal of cancer, 2013, Oct-01, Volume: 133, Issue:7

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Cell Survival; Cyclo

2013
JNK activation is required for TNFα-induced apoptosis in human hepatocarcinoma cells.
    International immunopharmacology, 2013, Volume: 17, Issue:1

    Topics: Anthracenes; Antioxidants; Apoptosis; Butylated Hydroxyanisole; Carcinoma, Hepatocellular; Caspases;

2013
Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:11

    Topics: Amino Acids, Dicarboxylic; Basic Helix-Loop-Helix Transcription Factors; Cell Hypoxia; Cell Line, Tu

2013
The anticancer effects of desferrioxamine on human breast adenocarcinoma and hepatocellular carcinoma cells.
    Cancer biomarkers : section A of Disease markers, 2014, Volume: 14, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Cycle Proteins; Deferoxamine; Fema

2014
Thalassemia major between liver and heart: Where we are now.
    Blood cells, molecules & diseases, 2015, Volume: 55, Issue:1

    Topics: Adolescent; Adult; beta-Thalassemia; Child; Child, Preschool; Cohort Studies; Deferiprone; Deferoxam

2015
CD146-targeted immunoPET and NIRF Imaging of Hepatocellular Carcinoma with a Dual-Labeled Monoclonal Antibody.
    Theranostics, 2016, Volume: 6, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Hepatocellular; CD146 Antigen; Cell Line; Deferoxamine;

2016
Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.
    World journal of gastroenterology, 2009, Sep-28, Volume: 15, Issue:36

    Topics: Basic-Leucine Zipper Transcription Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Deferoxamin

2009
Incidence of hepatocellular carcinoma in a thalassemia unit.
    Hemoglobin, 2010, Volume: 34, Issue:3

    Topics: Adult; Aged; Antibodies; Carcinoma, Hepatocellular; Chelation Therapy; Deferoxamine; Female; Hepatit

2010
Iron chelation for amelioration of liver ischemia-reperfusion injury.
    Hemoglobin, 2010, Volume: 34, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Animals; Deferoxamine; Disease Models, Animal; Female; Humans; Iron

2010
Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells.
    European journal of biochemistry, 2003, Volume: 270, Issue:8

    Topics: Animals; Deferiprone; Deferoxamine; Ferric Compounds; Hepatocytes; Iron; Iron Chelating Agents; Iron

2003
Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells.
    Physiological genomics, 2005, Aug-11, Volume: 22, Issue:3

    Topics: Algorithms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cobalt; Deferoxamine; DNA Primers; Down-Reg

2005
Deferoxamine enhances anti-proliferative effect of interferon-gamma against hepatocellular carcinoma cells.
    Cancer letters, 2007, Apr-08, Volume: 248, Issue:1

    Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell

2007
5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2007, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Aminolevulinic Acid; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; D

2007
Inhibitory effect of 6-formylpterin on HIF-1alpha protein accumulation.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:11

    Topics: Acetylcysteine; Antioxidants; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Deferoxamin

2007
Growth inhibition of hepatoma cells induced by vitamin K and its analogs.
    The Journal of biological chemistry, 1995, Nov-24, Volume: 270, Issue:47

    Topics: Amino Acid Sequence; Blotting, Northern; Carcinoma, Hepatocellular; Catalase; Cell Division; Cell Li

1995
Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Angiogenesis Inducing Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line; Chelating Agents;

1995
Visualization of the interaction of a regulatory protein with RNA in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Apr-15, Volume: 90, Issue:8

    Topics: Base Sequence; Carcinoma, Hepatocellular; Deferoxamine; DNA, Neoplasm; Gene Expression Regulation, N

1993
Modulation by iron loading and chelation of the uptake of non-transferrin-bound iron by human liver cells.
    Biochimica et biophysica acta, 1995, Apr-13, Volume: 1243, Issue:3

    Topics: Biological Transport; Carcinoma, Hepatocellular; Cell Death; Deferiprone; Deferoxamine; Diffusion; F

1995
The mechanism of antiproliferative effect of desferrioxamine on human hepatoma cell lines.
    Yonsei medical journal, 1994, Volume: 35, Issue:1

    Topics: Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Deferoxamine; Flow Cytometr

1994
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction.
    Blood, 1993, Dec-15, Volume: 82, Issue:12

    Topics: Base Sequence; Cell Hypoxia; Cell Line; Cell Nucleus; Cobalt; Deferoxamine; DNA-Binding Proteins; Er

1993
Effect of anticancer drugs and desferrioxamine in combination with radiation on hepatoma cell lines.
    Yonsei medical journal, 1993, Volume: 34, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Deferoxamine; Humans; Liver Neoplasms; Tumor Cells

1993
Differential cytotoxicity of iron chelators on malaria-infected cells versus mammalian cells.
    Blood, 1996, Jun-01, Volume: 87, Issue:11

    Topics: Animals; Antimalarials; Carcinoma, Hepatocellular; Cell Division; Chemical Phenomena; Chemistry, Phy

1996
Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1.
    The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23

    Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Ascorbic Acid; Aspirin; Carcinoma, Hepatocellular; Cell S

1997
Menadione-induced cell degeneration is related to lipid peroxidation in human cancer cells.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1998, Volume: 22, Issue:1

    Topics: Calcium; Carcinoma, Hepatocellular; Cell Death; Chelating Agents; Deferoxamine; Dicumarol; Glutathio

1998
Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity.
    Molecular pharmacology, 1998, Volume: 54, Issue:5

    Topics: Animals; Antimutagenic Agents; Base Sequence; Cell Hypoxia; Chelating Agents; Cobalt; Deferoxamine;

1998
Deferoxamine toxicity in hepatoma and primary rat cortical brain cultures.
    Human & experimental toxicology, 2001, Volume: 20, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Survival; Cerebral Cortex; Deferox

2001
Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect.
    The Journal of biological chemistry, 2002, Feb-22, Volume: 277, Issue:8

    Topics: Carcinoma, Hepatocellular; Cell Hypoxia; Cobalt; Deferoxamine; DNA-Binding Proteins; Gene Expression

2002
Effect of iron chelators on proliferation and iron uptake in hepatoma cells.
    Cancer, 2001, Dec-15, Volume: 92, Issue:12

    Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Membrane; Deferoxamine; Humans; Iron; Iron Chelating Age

2001
Acquisition, storage and release of iron by cultured human hepatoma cells.
    Journal of hepatology, 2002, Volume: 36, Issue:1

    Topics: Apoproteins; Carcinoma, Hepatocellular; Culture Media; Deferoxamine; Ferric Compounds; Ferritins; Hu

2002
Methyldopa binding to cells in culture.
    Acta pharmacologica et toxicologica, 1977, Volume: 40, Issue:1

    Topics: Acetaminophen; Allopurinol; Animals; Ascorbic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Defe

1977
Antitumor effect of deferoxamine on human hepatocellular carcinoma growing in athymic nude mice.
    Cancer, 1992, Oct-15, Volume: 70, Issue:8

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Deferoxamine; Drug Screening Assays, Antitumor; Hum

1992
Monitoring of iron(III) removal from biological sources using a fluorescent siderophore.
    Analytical biochemistry, 1992, Volume: 205, Issue:2

    Topics: 4-Chloro-7-nitrobenzofurazan; Carcinoma, Hepatocellular; Deferoxamine; Ferric Compounds; Fluorescenc

1992
Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1.
    The Journal of biological chemistry, 1990, Aug-25, Volume: 265, Issue:24

    Topics: Acute-Phase Proteins; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Deferoxamine; Ferr

1990
Inhibition of human hepatocellular carcinoma and hepatoblastoma cell lines by deferoxamine.
    Journal of medical virology, 1991, Volume: 34, Issue:1

    Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Survival; Deferoxamine; DNA, Viral; Edetic Acid;

1991
Effect of iron and desferoxamine on cell growth and in vitro ferritin synthesis in human hepatoma cell lines.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:4

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Deferoxamine; Ferrit

1990
[Present aspects of the treatment of hemochromatosis (apropos of 100 observations)].
    Annales de medecine interne, 1971, Volume: 122, Issue:12

    Topics: Adult; Alcoholic Intoxication; Bloodletting; Chelating Agents; Chondrocalcinosis; Deferoxamine; Diab

1971