deferoxamine has been researched along with Cancer of Colon in 16 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, this study aimed to clarify the role of PYCR1 and its interaction with SLC25A10 in a chemotherapeutic agent 5-fluorouracil (5-FU)'s toxicity to colorectal cancer cells." | 8.12 | The role of PYCR1 in inhibiting 5-fluorouracil-induced ferroptosis and apoptosis through SLC25A10 in colorectal cancer. ( Mai, Z; Qiu, X; Song, Y; Xia, W; Yang, X; Ye, Y; Zhang, M; Zhou, B, 2022) |
| " Therefore, this study aimed to clarify the role of PYCR1 and its interaction with SLC25A10 in a chemotherapeutic agent 5-fluorouracil (5-FU)'s toxicity to colorectal cancer cells." | 4.12 | The role of PYCR1 in inhibiting 5-fluorouracil-induced ferroptosis and apoptosis through SLC25A10 in colorectal cancer. ( Mai, Z; Qiu, X; Song, Y; Xia, W; Yang, X; Ye, Y; Zhang, M; Zhou, B, 2022) |
| "However, the role of PPARδ in colon cancer cells in a hypoxic tumor microenvironment is not fully understood." | 1.40 | PPARδ deficiency disrupts hypoxia-mediated tumorigenic potential of colon cancer cells. ( Hwang, DH; Jeong, E; Koo, JE; Kwak, MK; Lee, JY; Yeon, SH, 2014) |
| "Gold particles were not observed within the tumor cell cytoplasm." | 1.28 | Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice. ( Friend, DS; Hong, K; Huang, SK; Lee, KD; Papahadjopoulos, D, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, B | 1 |
| Mai, Z | 1 |
| Ye, Y | 1 |
| Song, Y | 1 |
| Zhang, M | 1 |
| Yang, X | 1 |
| Xia, W | 1 |
| Qiu, X | 1 |
| Brandt, KE | 1 |
| Falls, KC | 1 |
| Schoenfeld, JD | 1 |
| Rodman, SN | 1 |
| Gu, Z | 1 |
| Zhan, F | 1 |
| Cullen, JJ | 1 |
| Wagner, BA | 1 |
| Buettner, GR | 1 |
| Allen, BG | 1 |
| Berg, DJ | 1 |
| Spitz, DR | 1 |
| Fath, MA | 1 |
| Jeong, E | 1 |
| Koo, JE | 1 |
| Yeon, SH | 1 |
| Kwak, MK | 1 |
| Hwang, DH | 1 |
| Lee, JY | 1 |
| Moon, JH | 1 |
| Jeong, JK | 1 |
| Park, SY | 1 |
| Tavaré, R | 1 |
| Escuin-Ordinas, H | 1 |
| Mok, S | 1 |
| McCracken, MN | 1 |
| Zettlitz, KA | 1 |
| Salazar, FB | 1 |
| Witte, ON | 1 |
| Ribas, A | 1 |
| Wu, AM | 1 |
| Klenow, S | 1 |
| Glei, M | 1 |
| Ruggiero, A | 1 |
| Villa, CH | 1 |
| Holland, JP | 1 |
| Sprinkle, SR | 1 |
| May, C | 1 |
| Lewis, JS | 1 |
| Scheinberg, DA | 1 |
| McDevitt, MR | 1 |
| Yeung, HY | 1 |
| Lai, KP | 1 |
| Chan, HY | 1 |
| Mak, NK | 1 |
| Wagner, GF | 1 |
| Wong, CK | 1 |
| Woo, KJ | 1 |
| Lee, TJ | 1 |
| Park, JW | 1 |
| Kwon, TK | 1 |
| Nguyen, TD | 1 |
| Canada, AT | 1 |
| Nakajima, M | 1 |
| Shinoda, I | 1 |
| Samejima, Y | 1 |
| Miyauchi, H | 1 |
| Fukuwatari, Y | 1 |
| Hayasawa, H | 1 |
| Unno, N | 1 |
| Menconi, MJ | 1 |
| Fink, MP | 1 |
| Ryser, JE | 1 |
| Rose, K | 1 |
| Jones, R | 1 |
| Pelegrin, A | 1 |
| Donath, A | 1 |
| Egeli, R | 1 |
| Smith, A | 1 |
| Offord, RE | 1 |
| Huang, SK | 1 |
| Lee, KD | 1 |
| Hong, K | 1 |
| Friend, DS | 1 |
| Papahadjopoulos, D | 2 |
| Gabizon, A | 1 |
| Price, DC | 1 |
| Huberty, J | 1 |
| Bresalier, RS | 1 |
| Siegers, CP | 1 |
| Bumann, D | 1 |
| Baretton, G | 1 |
| Younes, M | 1 |
16 other studies available for deferoxamine and Cancer of Colon
| Article | Year |
|---|---|
The role of PYCR1 in inhibiting 5-fluorouracil-induced ferroptosis and apoptosis through SLC25A10 in colorectal cancer.
Topics: Adenocarcinoma; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Colorectal Neoplasms; Deferoxamine; | 2022 |
Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells.
Topics: Ascorbic Acid; Catalase; Cell Survival; Colonic Neoplasms; Deferoxamine; Ferric Compounds; Ferric Ox | 2018 |
PPARδ deficiency disrupts hypoxia-mediated tumorigenic potential of colon cancer cells.
Topics: Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colon; Colonic Neoplasms; Deferox | 2014 |
Deferoxamine inhibits TRAIL-mediated apoptosis via regulation of autophagy in human colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Blotting, Western; Colonic Neoplasms; Deferoxamine; HCT | 2015 |
An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.
Topics: Animals; Antibodies, Bispecific; CD8 Antigens; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Defero | 2016 |
New insight into the influence of carob extract and gallic acid on hemin induced modulation of HT29 cell growth parameters.
Topics: Adenocarcinoma; Adult; Antioxidants; Cell Proliferation; Colonic Neoplasms; Deferoxamine; Dose-Respo | 2009 |
Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes.
Topics: Actinium; Adenocarcinoma; Animals; Cell Line, Tumor; Colonic Neoplasms; Deferoxamine; Heterocyclic C | 2010 |
Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Deferoxamine; Female; Ferric Compounds; Ferricyanides; Glycopro | 2005 |
Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway.
Topics: Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Deferoxamine; Ferric Compounds; Fl | 2006 |
Modulation of human colonic T84 cell secretion by hydrogen peroxide.
Topics: Adenocarcinoma; Carbachol; Catalase; Chlorides; Colonic Neoplasms; Deferoxamine; Dithiothreitol; Ele | 1994 |
Lactoferrin as a suppressor of cell migration of gastrointestinal cell lines.
Topics: Adenocarcinoma; Animals; Apoproteins; Cattle; Cell Movement; Colonic Neoplasms; Deferoxamine; Digest | 1997 |
Nitric oxide-induced hyperpermeability of human intestinal epithelial monolayers is augmented by inhibition of the amiloride-sensitive Na(+)-H+ antiport: potential role of peroxynitrous acid.
Topics: Amiloride; Cell Membrane Permeability; Colonic Neoplasms; Deferoxamine; Humans; Intestinal Mucosa; M | 1997 |
Elimination of free radionuclide by a chelating agent improves tumor-to-nontumor ratios following radioimmunotargeting with antibody labeled with 67Ga.
Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Colonic Neoplasms; Deferoxamine; Gallium Radioiso | 1998 |
Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice.
Topics: Animals; Bone Marrow; Colloids; Colonic Neoplasms; Deferoxamine; Drug Stability; Female; Gallium Rad | 1992 |
Effect of liposome composition and other factors on the targeting of liposomes to experimental tumors: biodistribution and imaging studies.
Topics: Animals; Bleomycin; Chemistry, Pharmaceutical; Colonic Neoplasms; Deferoxamine; Drug Carriers; Galli | 1990 |
Dietary iron enhances the tumor rate in dimethylhydrazine-induced colon carcinogenesis in mice.
Topics: Alcohol Dehydrogenase; Animals; Cocarcinogenesis; Colonic Neoplasms; Deferoxamine; Diet; Dimethylhyd | 1988 |