deferoxamine has been researched along with Cancer of Cervix in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Importantly, the cotreatment of oxaliplatin with desferal significantly potentiated the oxaliplatin-elicited antitumoral effect in the oxaliplatin-resistant xenograft animal model without any toxic effect observed." | 1.43 | Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo. ( Chang, JY; Chen, SJ; Kuo, CC; Pan, HY; Tsou, TC; Yeh, SC, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, SJ | 1 |
| Kuo, CC | 1 |
| Pan, HY | 1 |
| Tsou, TC | 1 |
| Yeh, SC | 1 |
| Chang, JY | 1 |
| Nakamura, M | 1 |
| Bodily, JM | 1 |
| Beglin, M | 1 |
| Kyo, S | 1 |
| Inoue, M | 1 |
| Laimins, LA | 1 |
| Simonart, T | 2 |
| Boelaert, JR | 2 |
| Andrei, G | 2 |
| Clercq, ED | 1 |
| Snoeck, R | 2 |
| Mosselmans, R | 1 |
| Noel, JC | 1 |
| De Clercq, E | 1 |
4 other studies available for deferoxamine and Cancer of Cervix
| Article | Year |
|---|---|
Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo.
Topics: Active Transport, Cell Nucleus; Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocol | 2016 |
Hypoxia-specific stabilization of HIF-1alpha by human papillomaviruses.
Topics: Cell Hypoxia; Cell Line; Deferoxamine; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ke | 2009 |
Iron withdrawal strategies fail to prevent the growth of SiHa-induced tumors in mice.
Topics: Animals; Cell Division; Deferiprone; Deferoxamine; Female; Humans; Iron Chelating Agents; Iron, Diet | 2003 |
Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells.
Topics: Apoptosis; Cell Division; Deferiprone; Deferoxamine; Female; G1 Phase; Growth Inhibitors; HeLa Cells | 2002 |