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deferoxamine and Cancer, Embryonal

deferoxamine has been researched along with Cancer, Embryonal in 1 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"In view of the high relapse rate following chemotherapy for patients with advanced neuroblastoma (NB) and primitive neuroectodermal tumors (PNET), we designed a novel chemotherapy program which incorporated the iron chelator deferoxamine."5.07D-CECaT: a breakthrough for patients with neuroblastoma. ( Angioni, A; Boglino, C; Cozza, R; Deb, G; Donfrancesco, A; Helson, L; Jenkner, A; Landolfo, A; Maurizio, C, 1993)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Donfrancesco, A1
Deb, G1
Angioni, A1
Maurizio, C1
Cozza, R1
Jenkner, A1
Landolfo, A1
Boglino, C1
Helson, L1

Trials

1 trial available for deferoxamine and Cancer, Embryonal

ArticleYear
D-CECaT: a breakthrough for patients with neuroblastoma.
    Anti-cancer drugs, 1993, Volume: 4, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Carboplatin; Child; Child, Prescho

1993