Page last updated: 2024-10-25

deferoxamine and Burns

deferoxamine has been researched along with Burns in 4 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"We studied the effect of deferoxamine (DFO) infused after burns on hemodynamic stability as well as local and systemic inflammation and oxidant-induced lipid peroxidation."3.68Fluid resuscitation with deferoxamine prevents systemic burn-induced oxidant injury. ( Daryani, R; Demling, R; Knox, J; LaLonde, C; Youn, YK; Zhu, D, 1991)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Demling, R1
LaLonde, C2
Knox, J1
Youn, YK1
Zhu, D1
Daryani, R1
Demling, RH1
Till, GO2
Hatherill, JR1
Tourtellotte, WW1
Lutz, MJ1
Ward, PA2
Annesley, TM1

Other Studies

4 other studies available for deferoxamine and Burns

ArticleYear
Fluid resuscitation with deferoxamine prevents systemic burn-induced oxidant injury.
    The Journal of trauma, 1991, Volume: 31, Issue:4

    Topics: Animals; Burns; Deferoxamine; Edema; Fluid Therapy; Hydroxides; Hydroxyethyl Starch Derivatives; Iso

1991
Identification and modifications of the pulmonary and systemic inflammatory and biochemical changes caused by a skin burn.
    The Journal of trauma, 1990, Volume: 30, Issue:12 Suppl

    Topics: Allopurinol; Animals; Burns; Deferoxamine; Hemodynamics; Ibuprofen; Lipid Peroxidation; Liver; Lung;

1990
Lipid peroxidation and acute lung injury after thermal trauma to skin. Evidence of a role for hydroxyl radical.
    The American journal of pathology, 1985, Volume: 119, Issue:3

    Topics: Animals; Burns; Capillary Permeability; Chelating Agents; Deferoxamine; Dimethyl Sulfoxide; Hydroxid

1985
Cutaneous thermal burn and oxidant-mediated acute lung injury: appearance in serum of lung-related LDH isoenzyme.
    Journal of free radicals in biology & medicine, 1985, Volume: 1, Issue:5-6

    Topics: Animals; Burns; Deferoxamine; Free Radicals; Isoenzymes; L-Lactate Dehydrogenase; Lung; Lung Disease

1985