deferoxamine has been researched along with Burkitt Lymphoma in 1 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Burkitt Lymphoma: A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesize that the relatively higher bioavailability of nontransferrin iron in LIT cells, over that in HID cells, determines the differing responses observed under low-iron conditions." | 1.30 | The inability of cells to grow in low iron correlates with increasing activity of their iron regulatory protein (IRP). ( Kovár, J; Kriegerbecková, K; Kühn, LC; Musílková, J; Richardson, V; Seiser, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovár, J | 1 |
| Kühn, LC | 1 |
| Richardson, V | 1 |
| Seiser, C | 1 |
| Kriegerbecková, K | 1 |
| Musílková, J | 1 |
1 other study available for deferoxamine and Burkitt Lymphoma
| Article | Year |
|---|---|
The inability of cells to grow in low iron correlates with increasing activity of their iron regulatory protein (IRP).
Topics: Biological Transport; Burkitt Lymphoma; Cell Division; Culture Media; Deferoxamine; HeLa Cells; Huma | 1997 |