deferoxamine has been researched along with Bone Diseases in 44 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Bone Diseases: Diseases of BONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 g twice weekly for aluminum bone disease developed fever and bilateral calf pain caused by myonecrosis with gas gangrene." | 7.69 | Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine. ( Boelaert, JR; De Brauwer, E; Gordts, B; Lin, SH; Lin, YF; Shieh, SD; Van Landuyt, HW, 1996) |
| "Five patients with chronic renal failure, complicated by bone aluminum toxicity, were treated with deferoxamine (DFO)." | 5.27 | Precipitation of dialysis dementia by deferoxamine treatment of aluminum-related bone disease. ( Boykin, JL; Sherrard, DJ; Walker, JV, 1988) |
| "5 g twice weekly for aluminum bone disease developed fever and bilateral calf pain caused by myonecrosis with gas gangrene." | 3.69 | Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine. ( Boelaert, JR; De Brauwer, E; Gordts, B; Lin, SH; Lin, YF; Shieh, SD; Van Landuyt, HW, 1996) |
| "Aiming at a safe method in the diagnosis of aluminium-related bone disease (ARBD)/aluminium overload the low-dose desferrioxamine (DFO) test was developed." | 2.68 | Use of the low-dose desferrioxamine test to diagnose and differentiate between patients with aluminium-related bone disease, increased risk for aluminium toxicity, or aluminium overload. ( Barsoum, RS; Couttenye, MM; D'Haese, PC; De Broe, ME; Digenis, P; Fagalde, A; Goodman, WG; Lamberts, LV; Lemoniatou, E; Sotornik, I, 1995) |
| "The management of renal osteodystrophy should address all the pathogenetic mechanisms." | 2.38 | Diagnosis and management of bone disorders in chronic renal failure and dialyzed patients. ( Tzamaloukas, AH, 1990) |
| " Further experience with DFO is needed, both to identify the optimal dosage and to clarify the risks of long-term therapy in patients with renal failure." | 2.37 | Diagnosis of aluminum-related bone disease and treatment of aluminum toxicity with deferoxamine. ( Coburn, JW; Norris, KC, 1986) |
| "Congenital erythropoietic porphyria is a rare autosomal recessive disorder of haem biosynthesis caused by a deficiency of uroporphyrinogen III synthetase." | 1.31 | Congenital erythropoietic porphyria: dilemmas in present day management. ( Creamer, JD; Dawe, SA; Du Vivier, A; Peters, TJ, 2002) |
| "A male thalassemia major patient who developed bone and cartilage abnormalities with a standard dose of desferrioxamine (DFX) given subcutaneously from the age of 4 years was treated with the oral iron chelator deferiprone (L1)." | 1.31 | Treatment with deferiprone (L1) in a thalassemic patient with bone lesions due to desferrioxamine. ( Campisi, S; De Sanctis, V; Di Silvestro, G; Mangiagli, A; Urso, L, 2000) |
| "Five patients with dialysis encephalopathy were transferred to deionized water; all died after a variable period, 4 of progressive dementia." | 1.27 | The effect of low aluminum water and desferrioxamine on the outcome of dialysis encephalopathy. ( Bell, P; Meyers, AM; Milne, FJ; Sharf, B, 1983) |
| "Five patients with chronic renal failure, complicated by bone aluminum toxicity, were treated with deferoxamine (DFO)." | 1.27 | Precipitation of dialysis dementia by deferoxamine treatment of aluminum-related bone disease. ( Boykin, JL; Sherrard, DJ; Walker, JV, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (52.27) | 18.7374 |
| 1990's | 16 (36.36) | 18.2507 |
| 2000's | 4 (9.09) | 29.6817 |
| 2010's | 1 (2.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Donneys, A | 1 |
| Nelson, NS | 1 |
| Perosky, JE | 1 |
| Polyatskaya, Y | 1 |
| Rodriguez, JJ | 1 |
| Figueredo, C | 1 |
| Vasseli, CA | 1 |
| Ratliff, HC | 1 |
| Deshpande, SS | 1 |
| Kozloff, KM | 1 |
| Buchman, SR | 1 |
| Dawe, SA | 1 |
| Peters, TJ | 1 |
| Du Vivier, A | 1 |
| Creamer, JD | 1 |
| Sebes, JI | 1 |
| Pinstein, ML | 1 |
| Massie, JD | 1 |
| Scott, RL | 1 |
| Palmieri, GM | 1 |
| Williams, JW | 1 |
| Acchiardo, SR | 1 |
| Ihle, BU | 1 |
| Buchanan, MR | 1 |
| Stevens, B | 1 |
| Becker, GJ | 1 |
| Kincaid-Smith, P | 1 |
| Milne, FJ | 1 |
| Sharf, B | 1 |
| Bell, P | 1 |
| Meyers, AM | 1 |
| Economidou, J | 1 |
| Cronin, RE | 1 |
| MartÃn, C | 1 |
| Lens, XM | 1 |
| Prieto, A | 1 |
| Alonso, R | 1 |
| Correa, B | 1 |
| Arcocha, V | 1 |
| Soto, A | 1 |
| Ackrill, P | 2 |
| Day, JP | 2 |
| D'Haese, PC | 2 |
| Couttenye, MM | 2 |
| Goodman, WG | 2 |
| Lemoniatou, E | 1 |
| Digenis, P | 1 |
| Sotornik, I | 1 |
| Fagalde, A | 1 |
| Barsoum, RS | 1 |
| Lamberts, LV | 1 |
| De Broe, ME | 2 |
| Lin, SH | 1 |
| Shieh, SD | 1 |
| Lin, YF | 1 |
| De Brauwer, E | 1 |
| Van Landuyt, HW | 1 |
| Gordts, B | 1 |
| Boelaert, JR | 1 |
| Di Iorio, B | 1 |
| Terracciano, V | 1 |
| De Sanctis, V | 3 |
| Pinamonti, A | 1 |
| Di Palma, A | 1 |
| Sprocati, M | 2 |
| Atti, G | 1 |
| Gamberini, MR | 1 |
| Vullo, C | 1 |
| Jablonski, G | 1 |
| Klem, KH | 1 |
| Danielsen, CC | 1 |
| Mosekilde, L | 1 |
| Gordeladze, JO | 1 |
| Mazzaferro, S | 1 |
| Perruzza, I | 1 |
| Costantini, S | 1 |
| Pasquali, M | 1 |
| Onorato, L | 1 |
| Sardella, D | 1 |
| Giordano, R | 1 |
| Ciaralli, L | 1 |
| Ballanti, P | 1 |
| Bonucci, E | 1 |
| Cinotti, GA | 1 |
| Coen, G | 1 |
| Wonke, B | 1 |
| Nicholas, JC | 1 |
| Dawes, PT | 1 |
| Davies, SJ | 1 |
| Freemont, AJ | 1 |
| Caruso-Nicoletti, M | 1 |
| Di Bella, D | 1 |
| Pizzarelli, G | 1 |
| Leonardi, C | 1 |
| Sciuto, C | 1 |
| Coco, M | 1 |
| Di Gregorio, F | 1 |
| Mangiagli, A | 1 |
| Campisi, S | 1 |
| Di Silvestro, G | 1 |
| Urso, L | 1 |
| Stea, S | 1 |
| Savarino, L | 1 |
| Granchi, D | 1 |
| Visentin, M | 1 |
| Govoni, R | 1 |
| Pizzoferrato, A | 1 |
| Sun, SS | 1 |
| Tsai, SC | 1 |
| Hung, CJ | 1 |
| Tsai, PP | 1 |
| Kao, CH | 1 |
| Simon, M | 1 |
| Bourel, M | 1 |
| Pei, Y | 1 |
| Hercz, G | 1 |
| Greenwood, C | 1 |
| Sherrard, D | 1 |
| Segre, G | 1 |
| Manuel, A | 1 |
| Saiphoo, C | 1 |
| Fenton, S | 1 |
| Yaqoob, M | 1 |
| Ahmad, R | 1 |
| Roberts, N | 1 |
| Helliwell, T | 1 |
| Tzamaloukas, AH | 1 |
| Andress, DL | 1 |
| Nebeker, HG | 2 |
| Ott, SM | 1 |
| Endres, DB | 1 |
| Alfrey, AC | 1 |
| Slatopolsky, EA | 1 |
| Coburn, JW | 4 |
| Sherrard, DJ | 2 |
| Felsenfeld, AJ | 1 |
| Rodriguez, M | 1 |
| Coleman, M | 1 |
| Ross, D | 1 |
| Llach, F | 1 |
| Seyfert, UT | 1 |
| Didion, K | 1 |
| Albert, FW | 1 |
| Verbeelen, D | 1 |
| Smeyers-Verbeke, J | 1 |
| van Hooff, I | 1 |
| de Roy, G | 1 |
| Norris, KC | 3 |
| Terao, N | 2 |
| Suzuki, M | 2 |
| Homma, S | 1 |
| Asano, Y | 2 |
| Hosoda, S | 2 |
| Furuse, M | 1 |
| Ahmed, R | 1 |
| Howard, N | 1 |
| Nugent, ME | 1 |
| Sombolos, K | 1 |
| Kalekou, H | 1 |
| Barboutis, K | 1 |
| Tzarou, V | 1 |
| Umetani, N | 2 |
| Sato, N | 2 |
| Yoshida, A | 1 |
| Marumo, F | 3 |
| Walker, JV | 1 |
| Boykin, JL | 1 |
| Faugere, MC | 1 |
| Arnala, IO | 1 |
| Ritz, E | 1 |
| Malluche, HH | 1 |
| Kurokawa, K | 1 |
| Ogura, Y | 1 |
| Ono, T | 1 |
| Takahashi, Y | 1 |
| Hakim, RM | 1 |
| Stivelman, JC | 1 |
| Schulman, G | 1 |
| Fosburg, M | 1 |
| Wolfe, L | 1 |
| Imber, MJ | 1 |
| Lazarus, JM | 1 |
| Savory, J | 1 |
| Bertholf, RL | 1 |
| Wills, MR | 1 |
| Sizuki, M | 1 |
| Ando, Y | 1 |
| Kato, K | 1 |
| Suka, T | 1 |
11 reviews available for deferoxamine and Bone Diseases
| Article | Year |
|---|---|
Problems related to treatment of beta-thalassaemia major.
Topics: Adolescent; Adult; Bone Diseases; Child; Child, Preschool; Deferoxamine; Encephalitis; Female; Hormo | 1982 |
Southwestern Internal Medicine Conference: bone disease in kidney failure: diagnosis and management.
Topics: Aged; Biopsy; Bone and Bones; Bone Diseases; Calcitriol; Calcium; Chelating Agents; Chronic Kidney D | 1993 |
The use of desferrioximine in dialysis-associated aluminium disease.
Topics: Aluminum; Anemia; Bone Diseases; Brain Diseases; Deferoxamine; Humans; Kidney Failure, Chronic; Rena | 1993 |
Diagnosis and treatment of aluminium bone disease.
Topics: Aluminum; Bone and Bones; Bone Diseases; Deferoxamine; Humans; Parathyroid Hormone; Renal Dialysis | 1996 |
Bone disease in beta-thalassaemia major.
Topics: Anemia; beta-Thalassemia; Bone Diseases; Deferoxamine; Female; Humans; Male; Osteoporosis | 1998 |
[Idiopathic haemochromatosis. I. Clinical, biological and therapeutic aspects (author's transl)].
Topics: Bloodletting; Bone Diseases; Cardiomyopathies; Deferoxamine; Diabetes Mellitus; Female; Ferritins; H | 1979 |
Diagnosis and management of bone disorders in chronic renal failure and dialyzed patients.
Topics: Aluminum; Biopsy; Bone and Bones; Bone Diseases; Calcitriol; Chronic Kidney Disease-Mineral and Bone | 1990 |
Osteomalacia and bone disease arising from aluminum.
Topics: Aluminum; Animals; Bone and Bones; Bone Diseases; Deferoxamine; Humans; Kidney Failure, Chronic; Ost | 1986 |
Aluminum and iron overload in chronic dialysis.
Topics: Aluminum; Bone Diseases; Deferoxamine; Humans; Iron; Renal Dialysis; Uremia | 1988 |
Diagnosis of aluminum-related bone disease and treatment of aluminum toxicity with deferoxamine.
Topics: Aluminum; Bone Diseases; Deferoxamine; Hematologic Diseases; Humans; Muscular Diseases; Pain; Risk | 1986 |
Iliac crest bone biopsy for diagnosis of aluminum toxicity and a guide to the use of deferoxamine.
Topics: Aluminum; Biopsy; Bone Diseases; Deferoxamine; Humans; Needles | 1986 |
1 trial available for deferoxamine and Bone Diseases
| Article | Year |
|---|---|
Use of the low-dose desferrioxamine test to diagnose and differentiate between patients with aluminium-related bone disease, increased risk for aluminium toxicity, or aluminium overload.
Topics: Adult; Aged; Aluminum; Bone Diseases; Deferoxamine; Dose-Response Relationship, Drug; Female; Humans | 1995 |
32 other studies available for deferoxamine and Bone Diseases
| Article | Year |
|---|---|
Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation.
Topics: Amifostine; Angiography; Animals; Biomechanical Phenomena; Bone Density; Bone Diseases; Cytoprotecti | 2016 |
Congenital erythropoietic porphyria: dilemmas in present day management.
Topics: Adult; Anemia, Hemolytic; Blood Transfusion; Bone Diseases; Deferoxamine; Female; Hematopoietic Stem | 2002 |
Radiographic manifestations of aluminum-induced bone disease.
Topics: Adult; Aluminum; Antacids; Bone Diseases; Deferoxamine; Diphosphonates; Female; Fractures, Spontaneo | 1984 |
The efficacy of various treatment modalities on aluminium associated bone disease.
Topics: Adult; Alkaline Phosphatase; Aluminum; Bone and Bones; Bone Diseases; Deferoxamine; Humans; Kidney F | 1983 |
The effect of low aluminum water and desferrioxamine on the outcome of dialysis encephalopathy.
Topics: Adult; Aged; Aluminum; Bone Diseases; Brain Diseases; Deferoxamine; Dementia; Electroencephalography | 1983 |
[Verification of desferrioxamine ototoxicity by high-frequency audiometry in patients undergoing dialysis].
Topics: Adult; Aluminum; Audiometry; Bone Diseases; Deferoxamine; Dose-Response Relationship, Drug; Female; | 1994 |
Fatal Aeromonas hydrophila bacteremia in a hemodialysis patient treated with deferoxamine.
Topics: Aeromonas hydrophila; Aluminum; Antidotes; Bacteremia; Bone Diseases; Deferoxamine; Fatal Outcome; F | 1996 |
DFO low-dose therapy.
Topics: Aluminum; Bone Diseases; Deferoxamine; Dose-Response Relationship, Drug; Humans | 1996 |
Growth and development in thalassaemia major patients with severe bone lesions due to desferrioxamine.
Topics: Adolescent; Antidotes; beta-Thalassemia; Bone Diseases; Chelation Therapy; Child; Child, Preschool; | 1996 |
Aluminium-induced bone disease in uremic rats: effect of deferoxamine.
Topics: Adenylyl Cyclases; Aluminum; Animals; Biomechanical Phenomena; Bone and Bones; Bone Diseases; Bone R | 1996 |
Relative roles of intestinal absorption and dialysis-fluid-related exposure in the accumulation of aluminium in haemodialysis patients.
Topics: Adult; Aged; Aluminum; Bone and Bones; Bone Diseases; Deferoxamine; Dialysis Solutions; Female; Huma | 1997 |
Persisting aluminium-related bone disease after cadaveric renal transplantation.
Topics: Aluminum Hydroxide; Biopsy; Bone and Bones; Bone Diseases; Cadaver; Chelating Agents; Deferoxamine; | 1999 |
Growth failure and bone lesions due to desferrioxamine in thalassaemic patients.
Topics: beta-Thalassemia; Blood Transfusion; Bone Diseases; Chelating Agents; Child; Deferoxamine; Female; G | 1998 |
Treatment with deferiprone (L1) in a thalassemic patient with bone lesions due to desferrioxamine.
Topics: beta-Thalassemia; Body Height; Bone Diseases; Deferiprone; Deferoxamine; Growth Disorders; Humans; I | 2000 |
Osteochondrodystrophic lesions in chelated thalassemic patients: an histological analysis.
Topics: Adolescent; Biopsy; Bone Diseases; Cartilage; Chelating Agents; Child; Deferoxamine; Female; Fractur | 2000 |
Tc-99m MDP and Ga-67 citrate scintigraphic findings in sarcoidosis with osseous involvement.
Topics: Bone Diseases; Deferoxamine; Humans; Male; Middle Aged; Octreotide; Radionuclide Imaging; Radiopharm | 2001 |
Non-invasive prediction of aluminum bone disease in hemo- and peritoneal dialysis patients.
Topics: Aged; Aluminum; Bone Diseases; Deferoxamine; Evaluation Studies as Topic; Humans; Middle Aged; Parat | 1992 |
Low-dose desferrioxamine test for the diagnosis of aluminium-related bone disease in patients on regular haemodialysis.
Topics: Adult; Aluminum; Bone Diseases; Deferoxamine; Diagnostic Errors; Evaluation Studies as Topic; Female | 1991 |
Bone histologic response to deferoxamine in aluminum-related bone disease.
Topics: Aluminum; Bone and Bones; Bone Diseases; Deferoxamine; Female; Humans; Kidney Failure, Chronic; Male | 1987 |
Desferrioxamine therapy in hemodialysis patients with aluminum-associated bone disease.
Topics: Aluminum; Bone and Bones; Bone Diseases; Calcium; Deferoxamine; Diabetic Nephropathies; Female; Huma | 1989 |
Aluminium-related bone disease and haemodialysis.
Topics: Aluminum; Bone and Bones; Bone Diseases; Deferoxamine; Humans; Renal Dialysis | 1987 |
The effect of desferrioxamine on tissue aluminum concentration and bone histology in aluminum-loaded rats with renal failure.
Topics: Aluminum; Animals; Bone Diseases; Deferoxamine; Disease Models, Animal; Kidney Failure, Chronic; Mal | 1988 |
Rapid conversion from aluminium bone disease to hyperparathyroid bone disease by desferrioxamine.
Topics: Adult; Aluminum; Bone Diseases; Deferoxamine; Female; Fractures, Spontaneous; Humans; Hyperparathyro | 1988 |
Fatal phycomycosis in a hemodialyzed patient receiving deferoxamine.
Topics: Adult; Bone Diseases; Deferoxamine; Female; Humans; Mycoses; Nephritis, Hereditary; Renal Dialysis | 1988 |
[The deferoxamine loading test as a non-invasive method for diagnosing Al-related bone disease in hemodialysis patients; efficacy of deferoxamine therapy for the disease].
Topics: Adolescent; Adult; Aged; Aluminum; Bone Diseases; Deferoxamine; Female; Humans; Male; Middle Aged; R | 1988 |
Precipitation of dialysis dementia by deferoxamine treatment of aluminum-related bone disease.
Topics: Adult; Aluminum; Bone Diseases; Deferoxamine; Dementia; Female; Humans; Kidney Failure, Chronic; Mal | 1988 |
Loss of bone resulting from accumulation of aluminum in bone of patients undergoing dialysis.
Topics: Adolescent; Adult; Aged; Aluminum; Bone and Bones; Bone Diseases; Bone Resorption; Child; Child, Pre | 1986 |
Aluminum-associated bone disease: considerations on the pathogenesis and the effects of deferoxamine treatment.
Topics: Aluminum; Bone Diseases; Calcium; Deferoxamine; Humans; Osteoblasts; Renal Dialysis | 1987 |
Deferoxamine (DFO): the effectiveness for noninvasive diagnosis of aluminum-related bone disease, and for treatment of the disease.
Topics: Aluminum; Bone and Bones; Bone Diseases; Calcitriol; Calcium; Deafness; Deferoxamine; Eye; Humans; R | 1987 |
Iron overload and mobilization in long-term hemodialysis patients.
Topics: Adult; Bone Diseases; Child; Deferoxamine; Erythrocyte Transfusion; Female; Ferritins; Hemochromatos | 1987 |
Trace metals and degenerative diseases of the skeleton.
Topics: Aluminum; Bone Diseases; Deferoxamine; Humans; Renal Dialysis; Tissue Distribution | 1986 |
Kinetics of aluminium removal by desferrioxamine VIA hemodialysis in a case with aluminium bone disease.
Topics: Adult; Aluminum; Bone Diseases; Deferoxamine; Humans; Male; Renal Dialysis | 1985 |