deferoxamine has been researched along with Blood Poisoning in 21 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pathogenesis of sepsis is characterized by an overwhelming systemic inflammatory response that can lead to multiple organ failure." | 5.36 | Effects of N-acetylcysteine/deferoxamine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis. ( Cassol, OJ; Dal-Pizzol, F; Ferreira, GK; Gonçalves, CL; Petronilho, FC; Rezin, GT; Roesler, R; Scaini, G; Schwartsmann, G; Streck, EL, 2010) |
| "N-Acetylcysteine plus deferoxamine increased survival in the cecal ligation and puncture model when administered 3 and 12 hours after sepsis induction." | 3.96 | Stratification to predict the response to antioxidant. ( Constantino, L; Dal-Pizzol, F; Damásio, D; Fraga, C; Gonçalves, RC; Michels, M; Ritter, C, 2020) |
| "The pathogenesis of sepsis is characterized by an overwhelming systemic inflammatory response that can lead to multiple organ failure." | 1.36 | Effects of N-acetylcysteine/deferoxamine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis. ( Cassol, OJ; Dal-Pizzol, F; Ferreira, GK; Gonçalves, CL; Petronilho, FC; Rezin, GT; Roesler, R; Scaini, G; Schwartsmann, G; Streck, EL, 2010) |
| "Sepsis was induced in 40 rats using the cecal ligation and puncture method (CLP) and 20 rats randomly received twice subcutaneously DFX (total dose: 40 mg/kg)." | 1.32 | Deferoxamine administration in septic animals: improved survival and altered apoptotic gene expression. ( Antonakis, PT; Chatzigianni, E; Konstadoulakis, MM; Leandros, E; Memos, N; Messaris, E, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (52.38) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Ritter, C | 4 |
| Constantino, L | 2 |
| Michels, M | 1 |
| Gonçalves, RC | 1 |
| Fraga, C | 1 |
| Damásio, D | 1 |
| Dal-Pizzol, F | 5 |
| Andrades, M | 2 |
| de Oliveira, MR | 1 |
| Streck, EL | 2 |
| Fonseca Moreira, JC | 1 |
| Cassol, OJ | 1 |
| Rezin, GT | 1 |
| Petronilho, FC | 1 |
| Scaini, G | 1 |
| Gonçalves, CL | 1 |
| Ferreira, GK | 1 |
| Roesler, R | 1 |
| Schwartsmann, G | 1 |
| Crouser, ED | 1 |
| Messaris, E | 1 |
| Antonakis, PT | 1 |
| Memos, N | 1 |
| Chatzigianni, E | 1 |
| Leandros, E | 1 |
| Konstadoulakis, MM | 1 |
| Cross, CE | 1 |
| van Asbeck, BS | 1 |
| Halliwell, B | 1 |
| de Souza, LF | 1 |
| Pens Gelain, D | 1 |
| Bernard, EA | 1 |
| Moreira, JC | 1 |
| Barichello, T | 1 |
| Machado, RA | 1 |
| Valvassori, SS | 1 |
| Réus, GZ | 1 |
| Martins, MR | 1 |
| Petronilho, F | 1 |
| Quevedo, J | 1 |
| Gordts, B | 1 |
| Rummens, E | 1 |
| deMeirleir, L | 1 |
| Butzler, JP | 1 |
| Scharnetzky, M | 1 |
| König, R | 1 |
| Lakomek, M | 1 |
| Tillmann, W | 1 |
| Schröter, W | 1 |
| Moch, D | 1 |
| Schröppel, B | 1 |
| Schoenberg, MH | 1 |
| Schulz, HJ | 1 |
| Thorab, FC | 1 |
| Marzinzag, M | 1 |
| Hedlund, BE | 1 |
| Brückner, UB | 1 |
| Nouel, O | 1 |
| Voisin, PM | 1 |
| Vaucel, J | 1 |
| Dartois-Hoguin, M | 1 |
| Le Bris, M | 1 |
| Tielemans, C | 1 |
| Boelaert, J | 1 |
| Vergauwe, P | 1 |
| van Roost, G | 1 |
| Segaert, M | 1 |
| van Frachen, B | 1 |
| Lenclud, C | 1 |
| Masters, AP | 1 |
| Hopkinson, RB | 1 |
| Hoen, B | 1 |
| Renoult, E | 1 |
| Jonon, B | 1 |
| Kessler, M | 1 |
| Novotny, MJ | 1 |
| Laughlin, MH | 1 |
| Adams, HR | 1 |
| Hadjiminas, JM | 1 |
| Huang, CB | 1 |
| Löhr, H | 1 |
| Mofenson, HC | 1 |
| Caraccio, TR | 1 |
| Sharieff, N | 1 |
| Boelaert, JR | 1 |
| van Landuyt, HW | 1 |
| Valcke, YJ | 1 |
| Cantinieaux, B | 1 |
| Lornoy, WF | 1 |
| Vanherweghem, JL | 1 |
| Moreillon, P | 1 |
| Vandepitte, JM | 1 |
| Boyce, N | 1 |
| Wood, C | 1 |
| Holdsworth, S | 1 |
| Thomson, NM | 1 |
| Atkins, RC | 1 |
21 other studies available for deferoxamine and Blood Poisoning
| Article | Year |
|---|---|
Stratification to predict the response to antioxidant.
Topics: Acetylcysteine; Adult; Aged; Animals; Antioxidants; Deferoxamine; Humans; Male; Middle Aged; Prognos | 2020 |
Antioxidant treatment reverses organ failure in rat model of sepsis: role of antioxidant enzymes imbalance, neutrophil infiltration, and oxidative stress.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Deferoxamine; Disease Models, Animal; Kidney; Lung; | 2011 |
Effects of N-acetylcysteine/deferoxamine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis.
Topics: Acetylcysteine; Animals; Bombesin; Brain; Creatine Kinase; Deferoxamine; Electron Transport; Male; P | 2010 |
Therapeutic benefits of antioxidants during sepsis: is protection against oxidant-mediated tissue damage only half the story?
Topics: Acetylcysteine; Animals; Antioxidants; Deferoxamine; Free Radical Scavengers; Humans; Iron Chelating | 2004 |
Deferoxamine administration in septic animals: improved survival and altered apoptotic gene expression.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Caspases; Cytochromes c; Deferoxamine; Fr | 2004 |
More antioxidants in sepsis: still paved with uncertainties.
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Humans; | 2006 |
Mitochondrial superoxide production is related to the control of cytokine release from peritoneal macrophage after antioxidant treatment in septic rats.
Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Deferoxamine; Macrophages, Peritoneal; Male; Mitoc | 2007 |
Antioxidant treatment prevented late memory impairment in an animal model of sepsis.
Topics: Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Cecum; Deferoxamine; Disease Models, Anim | 2007 |
Yersinia pseudotuberculosis septicaemia in thalassaemia major.
Topics: Adolescent; Deferoxamine; Female; Humans; Sepsis; Thalassemia; Yersinia Infections; Yersinia pseudot | 1984 |
Prophylaxis of systemic yersinosis in thalassaemia major.
Topics: Child; Deferoxamine; Female; Humans; Risk; Sepsis; Thalassemia; Yersinia Infections | 1984 |
Protective effects of hydroxyethyl starch-deferoxamine in early sepsis.
Topics: Animals; Deferoxamine; Glutathione; Hydroxyethyl Starch Derivatives; Intestine, Small; Kidney; Lipid | 1995 |
[Yersinia enterocolitica septicemia associated with idiopathic hemochromatosis and deferoxamine therapy. A case].
Topics: Deferoxamine; Hemochromatosis; Humans; Infusions, Intravenous; Male; Middle Aged; Risk Factors; Seps | 1991 |
Deferoxamine does not increase the risk for bacteremia in hemodialysis patients.
Topics: Adolescent; Adult; Aged; Child; Deferoxamine; Female; Humans; Kidney Failure, Chronic; Male; Middle | 1989 |
Yersinia enterocolitica septicaemia.
Topics: Adult; Deferoxamine; Hemosiderosis; Humans; Sepsis; Thalassemia; Yersinia enterocolitica; Yersinia I | 1988 |
Septicemia due to Yersinia enterocolitica in a long-term hemodialysis patient after a single desferrioxamine administration.
Topics: Deferoxamine; Humans; Male; Middle Aged; Renal Dialysis; Sepsis; Yersinia enterocolitica; Yersinia I | 1988 |
Evidence for lack of importance of oxygen free radicals in Escherichia coli endotoxemia in dogs.
Topics: Animals; Cardiovascular System; Catalase; Deferoxamine; Dogs; Endotoxins; Escherichia coli Infection | 1988 |
Yersiniosis in acutely iron-loaded children treated with desferrioxamine.
Topics: Child; Deferoxamine; Humans; Infant; Iron; Sepsis; Yersinia Infections | 1988 |
[Yersinia septicemia in children with thalassaemia major].
Topics: Child; Child, Preschool; Deferoxamine; Female; Hemosiderosis; Humans; Male; Risk Factors; Sepsis; Th | 1987 |
Iron sepsis: Yersinia enterocolitica septicemia possibly caused by an overdose of iron.
Topics: Acute Disease; Deferoxamine; Diseases in Twins; Female; Humans; Infant; Iron; Male; Sepsis; Yersinia | 1987 |
The role of iron overload in Yersinia enterocolitica and Yersinia pseudotuberculosis bacteremia in hemodialysis patients.
Topics: Adult; Aged; Deferoxamine; Female; Ferritins; Humans; Iron; Male; Middle Aged; Renal Dialysis; Sepsi | 1987 |
Life-threatening sepsis complicating heavy metal chelation therapy with desferrioxamine.
Topics: Adult; Deferoxamine; Humans; Iron; Male; Renal Dialysis; Sepsis; Yersinia Infections | 1985 |