deferoxamine has been researched along with Bipolar Disorder in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Paradoxal sleep deprivation (PSD) in mice has been considered a good animal model of mania because it induces similar manic-like behavior, as well as producing the neurochemical alterations which have been observed in bipolar patients." | 1.42 | The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania. ( Amboni, RT; Arent, CO; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Quevedo, J; Resende, WR; Steckert, AV; Valvassori, SS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arent, CO | 1 |
| Valvassori, SS | 2 |
| Steckert, AV | 2 |
| Resende, WR | 1 |
| Dal-Pont, GC | 1 |
| Lopes-Borges, J | 1 |
| Amboni, RT | 1 |
| Bianchini, G | 1 |
| Quevedo, J | 2 |
| Petronilho, FC | 1 |
| Réus, GZ | 1 |
| Oliveira, VB | 1 |
| Boeck, CR | 1 |
| Kapczinski, F | 1 |
| Dal-Pizzol, F | 1 |
2 other studies available for deferoxamine and Bipolar Disorder
| Article | Year |
|---|---|
The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania.
Topics: Acetylcysteine; Aldehydes; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Brain; | 2015 |
Effect of N-acetylcysteine and/or deferoxamine on oxidative stress and hyperactivity in an animal model of mania.
Topics: Acetylcysteine; Animals; Bipolar Disorder; Central Nervous System Stimulants; Deferoxamine; Dextroam | 2008 |