Page last updated: 2024-10-25

deferoxamine and BCKD Deficiency

deferoxamine has been researched along with BCKD Deficiency in 2 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
" Because the neurotoxic mechanisms of MSUD are poorly understood, this study aimed to evaluate the effects of chronic administration of a BCAA pool (leucine, isoleucine and valine)."1.39Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model. ( Bogo, MR; Comim, CM; Ferreira, GC; Gelain, DP; Moreira, JC; Oliveira, GM; Pasquali, MA; Quevedo, J; Scaini, G; Schuck, PF; Streck, EL, 2013)
" Here, we investigated whether acute and chronic administration of a BCAA pool causes impairment of acquisition and retention of avoidance memory in young rats."1.38Antioxidant administration prevents memory impairment in an animal model of maple syrup urine disease. ( Comim, CM; Dominguini, D; Ferreira, GC; Jeremias, IC; Mina, F; Morais, MO; Pescador, B; Quevedo, J; Scaini, G; Schuck, PF; Streck, EL; Teodorak, BP, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scaini, G2
Teodorak, BP1
Jeremias, IC1
Morais, MO1
Mina, F1
Dominguini, D1
Pescador, B1
Comim, CM2
Schuck, PF2
Ferreira, GC2
Quevedo, J2
Streck, EL2
Oliveira, GM1
Pasquali, MA1
Gelain, DP1
Moreira, JC1
Bogo, MR1

Other Studies

2 other studies available for deferoxamine and BCKD Deficiency

ArticleYear
Antioxidant administration prevents memory impairment in an animal model of maple syrup urine disease.
    Behavioural brain research, 2012, May-16, Volume: 231, Issue:1

    Topics: Acetylcysteine; Amino Acids, Branched-Chain; Animals; Antioxidants; Deferoxamine; Disease Models, An

2012
Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model.
    Journal of inherited metabolic disease, 2013, Volume: 36, Issue:5

    Topics: Acetylcysteine; Amino Acids, Branched-Chain; Animals; Antioxidants; Brain-Derived Neurotrophic Facto

2013