deferoxamine has been researched along with Asystole in 14 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with beta-thalassemia major often present with severe anemia and must undergo continuous transfusion therapy, consequently developing iron overload leading to hemochromatosis." | 1.33 | Lack of prognostic value of normalized integrated backscatter analysis of myocardium in patients with thalassemia major: a long-term follow-up study. ( Ait-Ali, L; Bellotti, P; Derchi, G; Forni, G; Jambrik, Z; Picano, E, 2005) |
| "In the remaining dogs, a 15-minute cardiac arrest was induced with KCl." | 1.27 | Effect on biochemical markers of brain injury of therapy with deferoxamine or superoxide dismutase following cardiac arrest. ( Aust, SD; Bicknell, JS; Goosmann, M; Krause, GS; March, GG; Nayini, NR; White, BC, 1988) |
| "Animals subjected to cardiac arrest and resuscitation and standard intensive care (SIC) had LMWC iron levels of 37." | 1.27 | Post resuscitation iron delocalization and malondialdehyde production in the brain following prolonged cardiac arrest. ( Aust, SD; Bialek, H; Evans, AT; Huang, RR; Indrieri, RJ; Jacobs, WA; Komara, J; Nayini, NR; White, BC, 1985) |
| "Brain injury after cardiac arrest and resuscitation may occur, in part, by oxygen radical mechanisms." | 1.27 | Brain iron delocalization and lipid peroxidation following cardiac arrest. ( Bialick, HA; Evans, AT; Garritano, AM; Hoehner, TJ; Huang, RR; Indrieri, RJ; Jacobs, WA; Komara, JS; Krause, GS; Nayini, NR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, T | 1 |
| He, Q | 1 |
| Cheng, C | 1 |
| Li, H | 1 |
| Liang, L | 1 |
| Zhang, G | 1 |
| Su, C | 1 |
| Xiao, Y | 1 |
| Bradley, J | 1 |
| Peberdy, MA | 1 |
| Ornato, JP | 1 |
| Tang, W | 1 |
| Niu, X | 1 |
| Huang, WH | 1 |
| De Boer, B | 1 |
| Delriviere, L | 1 |
| Mou, LJ | 1 |
| Jeffrey, GP | 1 |
| Liachenko, S | 1 |
| Tang, P | 1 |
| Xu, Y | 1 |
| Jambrik, Z | 1 |
| Derchi, G | 1 |
| Picano, E | 1 |
| Ait-Ali, L | 1 |
| Forni, G | 1 |
| Bellotti, P | 1 |
| Greenblatt, DJ | 1 |
| Allen, MD | 1 |
| Kock-Weser, J | 1 |
| Rosenthal, RE | 1 |
| Chanderbhan, R | 1 |
| Marshall, G | 1 |
| Fiskum, G | 1 |
| Cerchiari, EL | 1 |
| Sclabassi, RJ | 1 |
| Safar, P | 1 |
| Hoel, TM | 1 |
| van Jaarsveld, H | 1 |
| Groenewald, AJ | 1 |
| Potgieter, GM | 1 |
| Barnard, SP | 1 |
| Vermaak, WJ | 1 |
| Barnard, HC | 1 |
| White, BC | 2 |
| Nayini, NR | 3 |
| Krause, GS | 2 |
| Aust, SD | 2 |
| March, GG | 1 |
| Bicknell, JS | 1 |
| Goosmann, M | 1 |
| Babbs, CF | 3 |
| Huang, RR | 2 |
| Indrieri, RJ | 2 |
| Evans, AT | 2 |
| Bialek, H | 1 |
| Jacobs, WA | 2 |
| Komara, J | 1 |
| Kompala, SD | 1 |
| Blaho, KE | 1 |
| Komara, JS | 1 |
| Bialick, HA | 1 |
| Garritano, AM | 1 |
| Hoehner, TJ | 1 |
1 review available for deferoxamine and Asystole
| Article | Year |
|---|---|
Role of iron ions in the genesis of reperfusion injury following successful cardiopulmonary resuscitation: preliminary data and a biochemical hypothesis.
Topics: Animals; Brain Ischemia; Deferoxamine; Free Radicals; Heart Arrest; Humans; Hydroxylation; Ions; Iro | 1985 |
13 other studies available for deferoxamine and Asystole
| Article | Year |
|---|---|
UAMC-3203 or/and Deferoxamine Improve Post-Resuscitation Myocardial Dysfunction Through Suppressing Ferroptosis in a Rat Model of Cardiac Arrest.
Topics: Animals; Cardiopulmonary Resuscitation; Cyclohexylamines; Deferoxamine; Disease Models, Animal; Ferr | 2022 |
Iron-induced oxidative rat liver injury after non-heart-beating warm ischemia is mediated by tumor necrosis factor α and prevented by deferoxamine.
Topics: Adenosine; Allopurinol; Animals; Aspartate Aminotransferases; Bile; Deferoxamine; Disease Models, An | 2014 |
Deferoxamine improves early postresuscitation reperfusion after prolonged cardiac arrest in rats.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Deferoxamine; Heart Arrest; He | 2003 |
Lack of prognostic value of normalized integrated backscatter analysis of myocardium in patients with thalassemia major: a long-term follow-up study.
Topics: Acoustics; Adolescent; Adult; beta-Thalassemia; Blood Transfusion; Cardiac Output, Low; Chelation Th | 2005 |
Accidental iron poisoning in childhood. Six cases including one fatality.
Topics: Child, Preschool; Deferoxamine; Female; Heart Arrest; Humans; Infant; Iron; Male; Pulmonary Edema; T | 1976 |
Prevention of post-ischemic brain lipid conjugated diene production and neurological injury by hydroxyethyl starch-conjugated deferoxamine.
Topics: Alkenes; Animals; Brain Ischemia; Deferoxamine; Free Radicals; Heart Arrest; Hydroxyethyl Starch Der | 1992 |
Effects of combined superoxide dismutase and deferoxamine on recovery of brainstem auditory evoked potentials and EEG after asphyxial cardiac arrest in dogs.
Topics: Animals; Asphyxia; Brain Stem; Deferoxamine; Dogs; Drug Therapy, Combination; Electroencephalography | 1990 |
The effect of allopurinol and deferrioxamine on rat heart mitochondrial oxidative phosphorylation after normothermic ischemic cardiac arrest and of reperfusion.
Topics: Adenosine Diphosphate; Allopurinol; Animals; Coronary Disease; Deferoxamine; Heart Arrest; In Vitro | 1988 |
Effect on biochemical markers of brain injury of therapy with deferoxamine or superoxide dismutase following cardiac arrest.
Topics: Animals; Brain Chemistry; Deferoxamine; Dogs; Heart Arrest; Lipid Peroxidation; Malondialdehyde; Pot | 1988 |
The post treatment experiment: an operational definition of reperfusion injury.
Topics: Allopurinol; Animals; Creatine Kinase; Deferoxamine; Disease Models, Animal; Heart Arrest; Ischemia; | 1988 |
Post resuscitation iron delocalization and malondialdehyde production in the brain following prolonged cardiac arrest.
Topics: Animals; Brain Ischemia; Deferoxamine; Dogs; Free Radicals; Heart Arrest; Iron Chelating Agents; Lid | 1985 |
Effect of deferoxamine on late deaths following CPR in rats.
Topics: Animals; Deferoxamine; Electrocardiography; Heart Arrest; Injections, Intravenous; Male; Rats; Rats, | 1986 |
Brain iron delocalization and lipid peroxidation following cardiac arrest.
Topics: Analysis of Variance; Animals; Brain; Deferoxamine; Dogs; Heart Arrest; Infusions, Parenteral; Iron; | 1986 |