Page last updated: 2024-10-25

deferoxamine and Asthma

deferoxamine has been researched along with Asthma in 2 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Asthma was induced in BALBc mice by ovalbumin, using aluminum hydroxide as an adjuvant."3.80Zn/Ga-DFO iron-chelating complex attenuates the inflammatory process in a mouse model of asthma. ( Berenshtein, E; Bibi, H; Brod, V; Chevion, M; Elenberg, Y; Eliashar, R; Faingersh, A; Landesberg, A; Pesin, J; Vinokur, V; Waisman, D; Yadid, M, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, M1
Ichinose, T1
Yoshida, S1
Nishikawa, M1
Sun, G1
Shibamoto, T1
Bibi, H1
Vinokur, V1
Waisman, D1
Elenberg, Y1
Landesberg, A1
Faingersh, A1
Yadid, M1
Brod, V1
Pesin, J1
Berenshtein, E1
Eliashar, R1
Chevion, M1

Other Studies

2 other studies available for deferoxamine and Asthma

ArticleYear
Role of iron and oxidative stress in the exacerbation of allergic inflammation in murine lungs caused by urban particulate matter <2.5 μm and desert dust.
    Journal of applied toxicology : JAT, 2019, Volume: 39, Issue:6

    Topics: Acetylcysteine; Animals; Asthma; Cytokines; Deferoxamine; Dust; Iron; Lipopolysaccharides; Male; Mic

2019
Zn/Ga-DFO iron-chelating complex attenuates the inflammatory process in a mouse model of asthma.
    Redox biology, 2014, Volume: 2

    Topics: Administration, Intranasal; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; De

2014