deferoxamine has been researched along with Arthritis, Rheumatoid in 19 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients with rheumatoid arthritis (RA) were treated with intraarticular deferoxamine or placebo to test the hypothesis that iron chelation decreased hydroxyl radical mediated lipid peroxidation in RA." | 9.06 | Deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis. ( Fox, IH; Fudman, EJ; Till, GO, 1987) |
| "Eleven patients with rheumatoid arthritis (RA) were treated with intraarticular deferoxamine or placebo to test the hypothesis that iron chelation decreased hydroxyl radical mediated lipid peroxidation in RA." | 5.06 | Deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis. ( Fox, IH; Fudman, EJ; Till, GO, 1987) |
| " In the present study, we evaluated RAc1 nano particle effects on hyperalgesia and liver hepcidin and serum IL-1β and TNF-α expression levels during acute and chronic phases of adjuvant-induced inflammation in male rats and compared its effects with Deferoxamine." | 3.91 | Anti-hyperalgesia effect of nanchelating based nano particle, RAc1, can be mediated via liver hepcidin expression modulation during persistent inflammation. ( Houshmandi, E; Kalanaky, S; Manaheji, H; Mirjafai, S; Mohammadi, M; Nazemian, V; Zaringhalam, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nazemian, V | 1 |
| Kalanaky, S | 1 |
| Manaheji, H | 1 |
| Houshmandi, E | 1 |
| Mohammadi, M | 1 |
| Zaringhalam, J | 1 |
| Mirjafai, S | 1 |
| Akiyama, M | 1 |
| Kaneko, Y | 1 |
| Hanaoka, H | 1 |
| Kuwana, M | 1 |
| Takeuchi, T | 1 |
| Kinderlerer, AR | 1 |
| Steinberg, R | 1 |
| Johns, M | 1 |
| Harten, SK | 1 |
| Lidington, EA | 1 |
| Haskard, DO | 1 |
| Maxwell, PH | 1 |
| Mason, JC | 1 |
| Lawson, AA | 1 |
| Owen, ET | 1 |
| Mowat, AG | 1 |
| Giordano, N | 2 |
| Fioravanti, A | 1 |
| Sancasciani, S | 1 |
| Marcolongo, R | 2 |
| Borghi, C | 1 |
| Maddali Bongi, S | 1 |
| Palermo, C | 1 |
| Bianucci, G | 1 |
| Salvarani, C | 1 |
| Baricchi, R | 1 |
| Lasagni, D | 1 |
| Boiardi, L | 1 |
| Piccinini, R | 1 |
| Brunati, C | 1 |
| Macchioni, P | 1 |
| Portioli, I | 1 |
| Hisakawa, N | 1 |
| Nishiya, K | 1 |
| Tahara, K | 1 |
| Matsumori, A | 1 |
| Hashimoto, K | 1 |
| Beren, J | 1 |
| Hill, SL | 1 |
| Diener-West, M | 1 |
| Rose, NR | 1 |
| Sorokina, LP | 1 |
| Di Lollo, F | 1 |
| Morini, PL | 1 |
| Fazzini, G | 1 |
| Niosi, L | 1 |
| Parkes, HG | 1 |
| Allen, RE | 1 |
| Furst, A | 1 |
| Blake, DR | 1 |
| Grootveld, MC | 1 |
| Magarò, M | 1 |
| Zoli, A | 1 |
| Altomonte, L | 1 |
| Mirone, L | 1 |
| Corvino, G | 1 |
| Storti, S | 1 |
| Marra, R | 1 |
| Ricerca, BM | 1 |
| Pagano, L | 1 |
| Di Cesare, L | 1 |
| Halliwell, B | 1 |
| Gutteridge, JM | 1 |
| Blake, D | 1 |
| Fudman, EJ | 1 |
| Till, GO | 1 |
| Fox, IH | 1 |
| Calabria, AA | 1 |
| Lalumera, M | 1 |
| Mazzullo, G | 1 |
| Cavallo, G | 1 |
| Morozzi, G | 1 |
| Polson, RJ | 2 |
| Jawad, AS | 1 |
| Bomford, A | 2 |
| Berry, H | 2 |
| Williams, R | 2 |
| Jawed, A | 1 |
| Karlsson, B | 1 |
| Lagercrantz, R | 1 |
| Brann, I | 1 |
| Strandberg, O | 1 |
| Reizenstein, P | 1 |
1 review available for deferoxamine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Acute kidney injury due to renal sarcoidosis during etanercept therapy: a case report and literature review.
Topics: Acute Kidney Injury; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Deferoxamine; D | 2015 |
1 trial available for deferoxamine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Deferoxamine; Double-Blind Method; Female; Ferritins; Humans; Hydroxid | 1987 |
17 other studies available for deferoxamine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Anti-hyperalgesia effect of nanchelating based nano particle, RAc1, can be mediated via liver hepcidin expression modulation during persistent inflammation.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Deferoxamine; Hepcidins; Humans; Hyperalges | 2019 |
Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Atorvastatin; CD55 Antigens; CD59 Antigens; Cells, | 2006 |
Nature of anaemia in rheumatoid arthritis. VII. Storage of iron in rheumatoid disease.
Topics: Adult; Anemia; Arthritis, Rheumatoid; Deferoxamine; Female; Hemoglobinometry; Humans; Iron; Male; Mi | 1967 |
Increased storage of iron and anaemia in rheumatoid arthritis: usefulness of desferrioxamine.
Topics: Adult; Aged; Anemia; Arthritis, Rheumatoid; Deferoxamine; Female; Ferritins; Humans; Iron; Male; Mid | 1984 |
[Sideropenic anemia in rheumatoid arthritis: diagnostic usefulness of serum ferritin, unsaturated transferrin and induced urinary siderosis].
Topics: Anemia, Hypochromic; Arthritis, Rheumatoid; Deferoxamine; Ferritins; Humans; Iron; Transferrin | 1983 |
Effects of desferrioxamine therapy on chronic disease anemia associated with rheumatoid arthritis.
Topics: Anemia; Arthritis, Rheumatoid; Chronic Disease; Deferoxamine; Dose-Response Relationship, Drug; Enzy | 1996 |
Down regulation by iron of prostaglandin E2 production by human synovial fibroblasts.
Topics: Aged; Arthritis, Rheumatoid; Cells, Cultured; Citric Acid; Deferoxamine; Depression, Chemical; Dinop | 1998 |
Effect of pre-loading oral glucosamine HCl/chondroitin sulfate/manganese ascorbate combination on experimental arthritis in rats.
Topics: Animals; Arthritis, Rheumatoid; Ascorbic Acid; Autoantibodies; Chondroitin Sulfates; Collagen; Defer | 2001 |
[Despheral test in diagnosis of iron stores in patients with rheumatoid polyarthritis].
Topics: Arthritis, Rheumatoid; Deferoxamine; Humans; Iron | 1975 |
[Desferrioxamine in the diagnosis of hypo-, normo-, and hypersiderotic hyposideremia].
Topics: Adult; Aged; Anemia, Hypochromic; Arthritis, Rheumatoid; Breast Neoplasms; Deferoxamine; Duodenal Ul | 1977 |
Speciation of non-transferrin-bound iron ions in synovial fluid from patients with rheumatoid arthritis by proton nuclear magnetic resonance spectroscopy.
Topics: Arthritis, Rheumatoid; Deferoxamine; Ferritins; Humans; Iron; Magnetic Resonance Spectroscopy; Synov | 1991 |
Iron chelation in rheumatoid arthritis: clinical and laboratory evaluation.
Topics: Adult; Arthritis, Rheumatoid; beta 2-Microglobulin; Deferoxamine; Drug Evaluation; Female; Ferritins | 1990 |
Metal ions and oxygen radical reactions in human inflammatory joint disease.
Topics: Arthritis, Rheumatoid; Bleomycin; Blood Bactericidal Activity; Deferoxamine; Ferritins; Free Radical | 1985 |
[In vitro study on the possible inflammatory mechanism of ferrous ions: effect on the production of oxygen free radicals].
Topics: Arthritis, Rheumatoid; Deferoxamine; Ferric Compounds; Ferrous Compounds; Humans; Hydroxides; Hydrox | 1985 |
Treatment of rheumatoid arthritis with desferrioxamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Deferoxamine; Drug Evaluation; Female; Humans; Infusions, Parent | 1986 |
Treatment of rheumatoid arthritis with desferrioxamine: relation between stores of iron before treatment and side effects.
Topics: Adult; Aged; Arthritis, Rheumatoid; Deferoxamine; Female; Humans; Iron; Male; Middle Aged | 1985 |
[The use of desferrioxamine in iron poisoning and hemosiderosis].
Topics: Arthritis, Rheumatoid; Child, Preschool; Deferoxamine; Hematopoietic System; Hemosiderosis; Humans; | 1965 |