deferoxamine has been researched along with Arteriosclerosis in 10 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to represent a general marker of oxidative stress and long-term damage to proteins in aging, atherosclerosis, and diabetes." | 7.69 | Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. ( Nerlich, AG; Schleicher, ED; Wagner, E, 1997) |
| "N(epsilon)-(Carboxymethyl)lysine (CML), a major product of oxidative modification of glycated proteins, has been suggested to represent a general marker of oxidative stress and long-term damage to proteins in aging, atherosclerosis, and diabetes." | 3.69 | Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. ( Nerlich, AG; Schleicher, ED; Wagner, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 7 (70.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Minqin, R | 2 |
| Watt, F | 2 |
| Huat, BT | 1 |
| Halliwell, B | 3 |
| Tilbrook, L | 1 |
| Cuaz-Pérolin, C | 1 |
| Furman, C | 1 |
| Larigauderie, G | 1 |
| Legedz, L | 1 |
| Lasselin, C | 1 |
| Copin, C | 1 |
| Jaye, M | 1 |
| Searfoss, G | 1 |
| Yu, KT | 1 |
| Duverger, N | 1 |
| Nègre-Salvayre, A | 1 |
| Fruchart, JC | 1 |
| Rouis, M | 1 |
| Yuan, XM | 1 |
| Li, W | 1 |
| Baird, SK | 1 |
| Carlsson, M | 1 |
| Melefors, O | 1 |
| Rajendran, R | 1 |
| Pan, N | 1 |
| Tan, BK | 1 |
| Ong, WY | 1 |
| Dai, L | 1 |
| Winyard, PG | 1 |
| Zhang, Z | 1 |
| Blake, DR | 1 |
| Morris, CJ | 1 |
| Schleicher, ED | 1 |
| Wagner, E | 1 |
| Nerlich, AG | 1 |
| Rabelink, TJ | 1 |
| Stroes, E | 1 |
| Ishikawa, K | 1 |
| Sugawara, D | 1 |
| Suzuki, K | 1 |
| Itabe, H | 1 |
| Maruyama, Y | 1 |
| Lusis, AJ | 1 |
| Smith, C | 1 |
| Mitchinson, MJ | 1 |
| Aruoma, OI | 1 |
10 other studies available for deferoxamine and Arteriosclerosis
| Article | Year |
|---|---|
Correlation of iron and zinc levels with lesion depth in newly formed atherosclerotic lesions.
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Deferoxamine; Diet, Atherogenic; Disease Progression; | 2003 |
Cross talk between iron metabolism and diabetes.
Topics: Aged; Amino Acids; Arteriosclerosis; Chromium; Cytokines; Deferoxamine; Diabetes Mellitus; Diabetes | 2004 |
REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.
Topics: Adaptor Proteins, Signal Transducing; Arteriosclerosis; Cell Death; Cell Line; Cell Line, Tumor; Cel | 2004 |
Secretion of ferritin by iron-laden macrophages and influence of lipoproteins.
Topics: Arteriosclerosis; Deferoxamine; Erythrocytes; Ferritins; Hemin; Hemoglobins; Humans; Iron; Iron Chel | 2004 |
The iron chelator desferrioxamine inhibits atherosclerotic lesion development and decreases lesion iron concentrations in the cholesterol-fed rabbit.
Topics: Animals; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Deferoxamine; Iron; Iron Chelating Age | 2005 |
Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin.
Topics: Arteriosclerosis; Ascorbic Acid; Chelating Agents; Deferoxamine; Ferritins; Iron; Kinetics; Lipid Pe | 1996 |
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.
Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Ch | 1997 |
Atherosclerosis: defeat of the defense?
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol, Dietary; Deferoxamine; Enzyme Inhibitors; Gene Expres | 2001 |
Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice.
Topics: Animals; Aorta; Arteriosclerosis; Blotting, Northern; Cholesterol, Dietary; Deferoxamine; Enzyme Inh | 2001 |
Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions.
Topics: Animals; Arteriosclerosis; Cations; Copper; Deferoxamine; Humans; Hydrogen Peroxide; Hydroxides; Hyd | 1992 |