deferoxamine has been researched along with Aqueductal Stenosis in 7 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine was administered intraperitoneally for 3 consecutive days after GMH/iron trichloride." | 1.48 | Targeting Germinal Matrix Hemorrhage-Induced Overexpression of Sodium-Coupled Bicarbonate Exchanger Reduces Posthemorrhagic Hydrocephalus Formation in Neonatal Rats. ( Ding, Y; Krafft, P; Li, Q; Wan, W; Wu, G; Yan, F; Zhan, Q; Zhang, JH; Zhang, Y, 2018) |
| "Post-hemorrhagic chronic hydrocephalus (PHCH) is a common complication after intraventricular hemorrhage (IVH)." | 1.42 | Deferoxamine alleviates chronic hydrocephalus after intraventricular hemorrhage through iron chelation and Wnt1/Wnt3a inhibition. ( Feng, H; Gong, G; Hu, R; Hu, S; Li, F; Meng, H; Yuan, Y, 2015) |
| "Deferoxamine treatment attenuated TBI-induced hydrocephalus and heme oxygenase-1 upregulation." | 1.40 | Deferoxamine attenuates acute hydrocephalus after traumatic brain injury in rats. ( Chen, Z; Hua, Y; Keep, RF; Xi, G; Zhao, J, 2014) |
| "The pathogenesis of posthemorrhagic hydrocephalus is not fully understood." | 1.40 | Role of hemoglobin and iron in hydrocephalus after neonatal intraventricular hemorrhage. ( Bazzi, AA; Garton, HJ; Garton, T; Keep, RF; Kilaru, H; Maher, CO; Muraszko, KM; Strahle, JM; Xi, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Q | 1 |
| Ding, Y | 1 |
| Krafft, P | 1 |
| Wan, W | 1 |
| Yan, F | 1 |
| Wu, G | 1 |
| Zhang, Y | 1 |
| Zhan, Q | 1 |
| Zhang, JH | 1 |
| Gao, C | 1 |
| Du, H | 1 |
| Hua, Y | 3 |
| Keep, RF | 4 |
| Strahle, J | 1 |
| Xi, G | 5 |
| Zhao, J | 1 |
| Chen, Z | 1 |
| Strahle, JM | 2 |
| Garton, T | 1 |
| Bazzi, AA | 1 |
| Kilaru, H | 1 |
| Garton, HJ | 2 |
| Maher, CO | 1 |
| Muraszko, KM | 1 |
| Meng, H | 1 |
| Li, F | 1 |
| Hu, R | 1 |
| Yuan, Y | 1 |
| Gong, G | 1 |
| Hu, S | 1 |
| Feng, H | 1 |
| Egashira, Y | 1 |
| Chaudhary, N | 1 |
| Pandey, AS | 1 |
| Garton, TP | 1 |
| He, Y | 1 |
7 other studies available for deferoxamine and Aqueductal Stenosis
| Article | Year |
|---|---|
Targeting Germinal Matrix Hemorrhage-Induced Overexpression of Sodium-Coupled Bicarbonate Exchanger Reduces Posthemorrhagic Hydrocephalus Formation in Neonatal Rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Cerebral Hemorrhage; Cerebrospinal Fluid; Chlorides; Ch | 2018 |
Role of red blood cell lysis and iron in hydrocephalus after intraventricular hemorrhage.
Topics: Animals; Cerebral Hemorrhage; Deferoxamine; Erythrocytes; Ferritins; Heme Oxygenase-1; Hemolysis; Hy | 2014 |
Deferoxamine attenuates acute hydrocephalus after traumatic brain injury in rats.
Topics: Acute Disease; Animals; Brain; Brain Injuries; Deferoxamine; Hydrocephalus; Iron; Lateral Ventricles | 2014 |
Role of hemoglobin and iron in hydrocephalus after neonatal intraventricular hemorrhage.
Topics: Animals; Animals, Newborn; Blotting, Western; Cerebral Hemorrhage; Deferoxamine; Disease Models, Ani | 2014 |
Deferoxamine alleviates chronic hydrocephalus after intraventricular hemorrhage through iron chelation and Wnt1/Wnt3a inhibition.
Topics: Animals; Blotting, Western; Brain; Cerebral Hemorrhage; Chronic Disease; Deferoxamine; Disease Model | 2015 |
Acute Brain Injury after Subarachnoid Hemorrhage.
Topics: Acute Disease; Acute-Phase Proteins; Animals; Brain Injuries; Brain Ischemia; Deferoxamine; Hemoglob | 2015 |
Hemoglobin-induced neuronal degeneration in the hippocampus after neonatal intraventricular hemorrhage.
Topics: Animals; Animals, Newborn; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cerebral Hemorrh | 2016 |