deferoxamine has been researched along with Anoxemia in 105 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Deferoxamine (DFO), a hypoxia-mimic compound, can activate the proliferation of ISCs." | 7.88 | Deferoxamine preconditioning activated hypoxia-inducible factor-1α and MyD88-dependent Toll-like receptor 4 signaling in intestinal stem cells. ( Chen, Y; Lee, CH; Tsai, YH; Tseng, BY; Tseng, SH; Yang, XQ; Yao, CL, 2018) |
| "The accumulation of hypoxia-inducible factor-1α (HIF-1α) is under the influence of hydrogen sulfide (H(2) S), which regulates hypoxia responses." | 7.78 | Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α. ( Teng, H; Wang, R; Wu, B; Wu, L; Yang, G, 2012) |
| "Preconditioning with hypoxia and hypoxia-mimetic compounds cobalt chloride (CoCl2) and desferrioxamine (DFX) protects against hypoxic-ischemic (HI) injury in neonatal rat brain." | 7.74 | Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats. ( Beart, PM; Callaway, JK; Jones, NM; Kardashyan, L; Lee, EM, 2008) |
| "On isolated working right heart from rabbit tissue oxygen content as an indicator of function of oxygen transport and storage was observed by moderate hypoxia, hypoxia with deferoxamine (1) and iron infusion." | 7.68 | Deferoxamine (Desferal) improves the content of oxygen in myocardial tissues during recovery after hypoxia in isolated rabbit heart. ( Jacobsohn, E; Löwe, H, 1992) |
| " Through this new system combined with molecular biological methods, the changes of metabolites in TCA cycle of BV2 cells and drug metabolism of Scutellarin can be determined in real-time." | 5.91 | Metabolites from scutellarin alleviating deferoxamine-induced hypoxia injury in BV2 cells cultured on microfluidic chip combined with a mass spectrometer. ( Chen, S; Fan, F; Li, Y; Lin, JM; Meng, XL; Xu, N; Zeng, J; Zhang, Y, 2023) |
| "A deferoxamine-induced increase in HIF-1α/VEGF-A expression was also confirmed by western blot." | 5.72 | Activation of HIF-1α/VEGF-A pathway by deferoxamine ameliorates retinal hypoxia in a rat subarachnoid hemorrhage model. ( Deji, QZ; Deng, HJ; Gao, SQ; Han, YL; Liu, XL; Wang, X; Zhaba, WD; Zhou, ML, 2022) |
| " In addition, DFA saturated with iron did not completely reverse the effects of DFA, suggesting a mechanism(s) beyond a reduction in the bioavailability of iron." | 5.35 | Deferoxamine mimics the pattern of hypoxia-related injury at the microvasculature. ( Bartolome, S; Buch, S; Casillan, AJ; Dhillon, NK; O'Brien-Ladner, AR; Wood, JG, 2009) |
| "DPC on agarose-coated plates were treated with hypoxia and the HMA dimethyloxallyl glycine (DMOG), desferrioxamine (DFO) and L-mimosine (L-MIM)." | 3.88 | Formation of spheroids by dental pulp cells in the presence of hypoxia and hypoxia mimetic agents. ( Agis, H; Janjić, K; Lilaj, B; Moritz, A, 2018) |
| " Deferoxamine (DFO), a hypoxia-mimic compound, can activate the proliferation of ISCs." | 3.88 | Deferoxamine preconditioning activated hypoxia-inducible factor-1α and MyD88-dependent Toll-like receptor 4 signaling in intestinal stem cells. ( Chen, Y; Lee, CH; Tsai, YH; Tseng, BY; Tseng, SH; Yang, XQ; Yao, CL, 2018) |
| " As hypoxia has a role in altering the expression of proteins involved in iron regulation, this study was aimed at examining the interaction between hypoxia inducible factor (HIF)-1α and proteins involved in iron transport in microglial cells, and evaluating the mechanistic action of deferoxamine and KC7F2 (an inhibitor of HIF-1α) in iron mediated hypoxic injury." | 3.80 | Hypoxia inducible factor-1α mediates iron uptake which induces inflammatory response in amoeboid microglial cells in developing periventricular white matter through MAP kinase pathway. ( Kaur, C; Ling, EA; Rathnasamy, G, 2014) |
| " The relative luciferase activities were measured under various durations of hypoxia (6, 12, 18, and 24 h), O2 concentrations (1, 2, 4, 8, and 16 %), and various concentrations of deferoxamine mesylate (20, 40, 80, 160, and 320 µg/mL growth medium)." | 3.80 | Detailed assessment of gene activation levels by multiple hypoxia-responsive elements under various hypoxic conditions. ( Hata, H; Inubushi, M; Jin, YN; Kitagawa, Y; Murai, C; Saga, T; Takeuchi, Y; Tsuji, AB, 2014) |
| "The accumulation of hypoxia-inducible factor-1α (HIF-1α) is under the influence of hydrogen sulfide (H(2) S), which regulates hypoxia responses." | 3.78 | Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α. ( Teng, H; Wang, R; Wu, B; Wu, L; Yang, G, 2012) |
| "Preconditioning with hypoxia and hypoxia-mimetic compounds cobalt chloride (CoCl2) and desferrioxamine (DFX) protects against hypoxic-ischemic (HI) injury in neonatal rat brain." | 3.74 | Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats. ( Beart, PM; Callaway, JK; Jones, NM; Kardashyan, L; Lee, EM, 2008) |
| " Previous studies have shown that hypoxia or hypoxia-mimetic agents (cobalt chloride [CoCl2] or deferoxamine [DFX]) limit myocyte necrosis by upregulating the transcription factor hypoxia-inducible factor." | 3.73 | Thoracic Surgery Directors Association Award. Cobalt chloride pretreatment attenuates myocardial apoptosis after hypothermic circulatory arrest. ( Guyton, RA; Halkos, ME; Jiang, R; Kanter, KR; Kerendi, F; Kin, H; Kirshbom, PM; Vinten-Johansen, J; Wang, NP; Zhao, ZQ, 2006) |
| "BeWo cells were incubated with deferoxamine or cobalt chloride under normoxia and hypoxia." | 3.72 | Transcriptional effects of hypoxia on fusiogenic syncytin and its receptor ASCT2 in human cytotrophoblast BeWo cells and in ex vivo perfused placental cotyledons. ( Dötsch, J; Fusch, C; Knerr, I; Linnemann, K; Meissner, U; Rascher, W; Weigel, C, 2003) |
| " To probe involvement of the transcription factor hypoxia-induced factor-1 (HIF-1) in hexokinase (HK) II expression in human pulmonary cells, A549 cells and small-airway epithelial cells (SAECs) were exposed to stimuli such as hypoxia, deferoxamine (DFO), and metal ions." | 3.70 | Hypoxia induces hexokinase II gene expression in human lung cell line A549. ( Ahmad, A; Ahmad, S; Allen, CB; Deeb, SS; Malkki, M; Riddle, SR; Schneider, BK; White, CW, 2000) |
| " Apoptosis induced by asbestos, but not by actinomycin D, was inhibited by extracellular catalase, superoxide dismutase in the presence of catalase, hypoxia (8% oxygen), deferoxamine, 3-aminobenzamide [an inhibitor of poly(ADP-ribosyl) polymerase], and cytochalasin B." | 3.69 | Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species. ( Boylan, AM; Broaddus, VC; Ernst, JD; Scavo, LM; Yang, L, 1996) |
| " This study investigated the effects of increased antioxidants (administration of water-soluble fullerenol-1 and pre-exposure to chronic hypoxia) as well as an iron-chelating agent (deferoxamine) on exsanguination-induced noncholinergic airway constriction in guinea-pigs." | 3.69 | Water-soluble fullerene derivatives attenuate exsanguination-induced bronchoconstriction of guinea-pigs. ( Chiang, LY; Lai, YL, 1997) |
| "On isolated working right heart from rabbit tissue oxygen content as an indicator of function of oxygen transport and storage was observed by moderate hypoxia, hypoxia with deferoxamine (1) and iron infusion." | 3.68 | Deferoxamine (Desferal) improves the content of oxygen in myocardial tissues during recovery after hypoxia in isolated rabbit heart. ( Jacobsohn, E; Löwe, H, 1992) |
| "Deferoxamine (DFO) is an iron chelator with FDA approval for the clinical treatment of iron excess." | 3.01 | Advances in Hypoxia-Inducible Factor-1 ( Chang, B; Pang, Y; Wang, H; Zhou, Y; Zhu, Y, 2023) |
| "The onset of tissue hypoxemia coincides with the stabilization of hypoxia-inducible factor (HIF) and transcription of downstream HIF-mediated processes." | 1.91 | Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders. ( Ainslie, PN; Anholm, JD; Gasho, C; Hoiland, RL; Patrician, A; Subedi, P; Tymko, MM; Willie, C, 2023) |
| " Through this new system combined with molecular biological methods, the changes of metabolites in TCA cycle of BV2 cells and drug metabolism of Scutellarin can be determined in real-time." | 1.91 | Metabolites from scutellarin alleviating deferoxamine-induced hypoxia injury in BV2 cells cultured on microfluidic chip combined with a mass spectrometer. ( Chen, S; Fan, F; Li, Y; Lin, JM; Meng, XL; Xu, N; Zeng, J; Zhang, Y, 2023) |
| "A deferoxamine-induced increase in HIF-1α/VEGF-A expression was also confirmed by western blot." | 1.72 | Activation of HIF-1α/VEGF-A pathway by deferoxamine ameliorates retinal hypoxia in a rat subarachnoid hemorrhage model. ( Deji, QZ; Deng, HJ; Gao, SQ; Han, YL; Liu, XL; Wang, X; Zhaba, WD; Zhou, ML, 2022) |
| "Deferoxamine mesylate treatment also enhanced PLAP-1 expression in HPDLs." | 1.72 | Reciprocal role of PLAP-1 in HIF-1α-mediated responses to hypoxia. ( Bhongsatiern, P; Hirai, A; Iwayama, T; Kawakami, K; Kawasaki, K; Morimoto, C; Murakami, S; Murata, M; Sawada, K; Shimomura, J; Takedachi, M; Yamada, S; Yamamoto, S, 2022) |
| "Accordingly, three bladder cancer cell lines (T24, 5637, and HT1376) representative of two distinct carcinogenesis pathways to invasive cancer (FGFR3/CCND1 and E2F3/RB1) were used." | 1.43 | Reference Genes for Addressing Gene Expression of Bladder Cancer Cell Models under Hypoxia: A Step Towards Transcriptomic Studies. ( Ferreira, JA; Gaiteiro, C; Lima, L; Neves, M; Peixoto, A; Santos, LL; Soares, J, 2016) |
| "Perinatal anoxia under hyperthermic conditions intensified oxidative stress and depleted the pool of antioxidant enzymes." | 1.43 | Deferoxamine improves antioxidative protection in the brain of neonatal rats: The role of anoxia and body temperature. ( Caputa, M; Kletkiewicz, H; Mila-Kierzenkowska, C; Nowakowska, A; Rogalska, J; Siejka, A; Woźniak, A, 2016) |
| "Half of the rats exposed to anoxia under extremely hyperthermic conditions (39 °C) were injected with DF." | 1.43 | Deferoxamine prevents cerebral glutathione and vitamin E depletions in asphyxiated neonatal rats: role of body temperature. ( Caputa, M; Kletkiewicz, H; Mila-Kierzenkowska, C; Nowakowska, A; Rogalska, J; Siejka, A; Woźniak, A, 2016) |
| " In addition, DFA saturated with iron did not completely reverse the effects of DFA, suggesting a mechanism(s) beyond a reduction in the bioavailability of iron." | 1.35 | Deferoxamine mimics the pattern of hypoxia-related injury at the microvasculature. ( Bartolome, S; Buch, S; Casillan, AJ; Dhillon, NK; O'Brien-Ladner, AR; Wood, JG, 2009) |
| "Half of the rats exposed to anoxia under hyperthermic conditions were injected with deferoxamine (DF), immediately after anoxia and 24 h later." | 1.33 | Effect of neonatal body temperature on postanoxic, potentially neurotoxic iron accumulation in the rat brain. ( Caputa, M; Danielisova, V; Rogalska, J, 2006) |
| "Mechanisms for survival under anoxia are HIF-1alpha independent in Caenorhabditis elegans and, thus, differ from the hypoxic response." | 1.32 | Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells. ( Ameri, K; Hai, T; Harris, AL; Lewis, CE; Raida, M; Sowter, H, 2004) |
| "During anoxia, protein and nucleic acid oxidation did not change significantly." | 1.30 | Proteins but not nucleic acids are molecular targets for the free radical attack during reoxygenation of rat hepatocytes. ( Bernardi, M; Caraceni, P; Colantoni, A; De Maria, N; Floyd, RA; Maidt, ML; Pye, Q; Roberts, L; Ryu, HS; Van Thiel, DH, 1997) |
| "Oxygen delivery was maintained during hypoxemia by increasing cardiopulmonary bypass flow and hematocrit level." | 1.29 | Studies of hypoxemic/reoxygenation injury: without aortic clamping. IV. Role of the iron-catalyzed pathway: deferoxamine. ( Buckberg, GD; Ihnken, K; Morita, K; Sherman, MP; Young, HH, 1995) |
| "During anoxia, LDH release was substantially reduced at acidotic pH (pH 6." | 1.28 | Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox. ( Currin, RT; Gores, GJ; Lemasters, JJ; Thurman, RG, 1991) |
| "The effect of anoxia and reoxygenation on the synthesis and secretion of tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) was studied in primary cultures of human umbilical vein endothelial cells." | 1.28 | Oxygen radicals generated during anoxia followed by reoxygenation reduce the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in human endothelial cell culture. ( Collen, D; Doherty, JM; Shatos, MA; Stump, DC; Thompson, EA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.95) | 18.7374 |
| 1990's | 14 (13.33) | 18.2507 |
| 2000's | 55 (52.38) | 29.6817 |
| 2010's | 26 (24.76) | 24.3611 |
| 2020's | 9 (8.57) | 2.80 |
| Authors | Studies |
|---|---|
| Theriault, JR | 1 |
| Felts, AS | 1 |
| Bates, BS | 1 |
| Perez, JR | 1 |
| Palmer, M | 1 |
| Gilbert, SR | 1 |
| Dawson, ES | 1 |
| Engers, JL | 1 |
| Lindsley, CW | 1 |
| Emmitte, KA | 1 |
| Takedachi, M | 1 |
| Yamamoto, S | 1 |
| Kawasaki, K | 1 |
| Shimomura, J | 1 |
| Murata, M | 1 |
| Morimoto, C | 1 |
| Hirai, A | 1 |
| Kawakami, K | 1 |
| Bhongsatiern, P | 1 |
| Iwayama, T | 1 |
| Sawada, K | 1 |
| Yamada, S | 1 |
| Murakami, S | 1 |
| Jones, NM | 2 |
| Nathanson, AD | 1 |
| Chell, S | 1 |
| DeAngelis, E | 1 |
| Whelan, G | 1 |
| Willé, D | 1 |
| Cheng, K | 1 |
| Terán, G | 1 |
| Li, H | 1 |
| Catrina, SB | 1 |
| Liu, R | 1 |
| Brighenti, S | 1 |
| Zheng, X | 1 |
| Grünler, J | 1 |
| Nylén, S | 1 |
| Carow, B | 1 |
| Rottenberg, ME | 1 |
| Deji, QZ | 1 |
| Wang, X | 2 |
| Zhaba, WD | 1 |
| Deng, HJ | 1 |
| Han, YL | 1 |
| Gao, SQ | 1 |
| Liu, XL | 1 |
| Zhou, ML | 1 |
| Zhu, Y | 2 |
| Chang, B | 2 |
| Pang, Y | 2 |
| Wang, H | 2 |
| Zhou, Y | 2 |
| Patrician, A | 1 |
| Willie, C | 1 |
| Hoiland, RL | 1 |
| Gasho, C | 1 |
| Subedi, P | 1 |
| Anholm, JD | 1 |
| Tymko, MM | 1 |
| Ainslie, PN | 1 |
| Chen, S | 1 |
| Fan, F | 1 |
| Zhang, Y | 2 |
| Zeng, J | 1 |
| Li, Y | 2 |
| Xu, N | 1 |
| Meng, XL | 1 |
| Lin, JM | 1 |
| Huang, Y | 1 |
| He, N | 1 |
| Kang, Q | 1 |
| Shen, D | 1 |
| Wang, Y | 1 |
| Chen, L | 1 |
| Hadidi, L | 1 |
| Constantin, J | 1 |
| Dalisson, B | 1 |
| Vieira, D | 1 |
| Drager, J | 2 |
| Harvey, E | 1 |
| Merle, G | 1 |
| Harada, T | 1 |
| Hirose, K | 1 |
| Wada, Y | 1 |
| Sato, M | 1 |
| Ichise, K | 1 |
| Aoki, M | 1 |
| Kato, T | 1 |
| Takeda, K | 2 |
| Takai, Y | 1 |
| Ramirez-GarciaLuna, JL | 1 |
| Kumar, A | 1 |
| Gbureck, U | 1 |
| Harvey, EJ | 1 |
| Barralet, JE | 1 |
| Bellanti, F | 1 |
| Janjić, K | 1 |
| Lilaj, B | 1 |
| Moritz, A | 1 |
| Agis, H | 1 |
| Chen, Y | 1 |
| Yang, XQ | 1 |
| Tseng, BY | 1 |
| Tsai, YH | 1 |
| Tseng, SH | 1 |
| Lee, CH | 1 |
| Yao, CL | 1 |
| Vrtačnik, P | 1 |
| Zupan, J | 1 |
| Mlakar, V | 1 |
| Kranjc, T | 1 |
| Marc, J | 1 |
| Kern, B | 1 |
| Ostanek, B | 1 |
| Rathnasamy, G | 2 |
| Ling, EA | 2 |
| Kaur, C | 2 |
| Takeuchi, Y | 1 |
| Inubushi, M | 1 |
| Jin, YN | 1 |
| Murai, C | 1 |
| Tsuji, AB | 1 |
| Hata, H | 1 |
| Kitagawa, Y | 1 |
| Saga, T | 1 |
| Kletkiewicz, H | 2 |
| Nowakowska, A | 3 |
| Siejka, A | 2 |
| Mila-Kierzenkowska, C | 2 |
| Woźniak, A | 2 |
| Caputa, M | 4 |
| Rogalska, J | 4 |
| Lima, L | 1 |
| Gaiteiro, C | 1 |
| Peixoto, A | 1 |
| Soares, J | 1 |
| Neves, M | 1 |
| Santos, LL | 1 |
| Ferreira, JA | 1 |
| Burnley-Hall, N | 1 |
| Willis, G | 1 |
| Davis, J | 1 |
| Rees, DA | 1 |
| James, PE | 1 |
| Pollard, PJ | 1 |
| Loenarz, C | 1 |
| Mole, DR | 1 |
| McDonough, MA | 1 |
| Gleadle, JM | 2 |
| Schofield, CJ | 1 |
| Ratcliffe, PJ | 3 |
| Bartolome, S | 1 |
| Dhillon, NK | 1 |
| Buch, S | 1 |
| Casillan, AJ | 1 |
| Wood, JG | 1 |
| O'Brien-Ladner, AR | 1 |
| Box, AH | 1 |
| Yuen, C | 1 |
| Ponjevic, D | 1 |
| Fick, GH | 1 |
| Demetrick, DJ | 1 |
| Smith, TG | 1 |
| Balanos, GM | 2 |
| Croft, QP | 1 |
| Talbot, NP | 1 |
| Dorrington, KL | 3 |
| Robbins, PA | 3 |
| Joyner, MJ | 1 |
| Johnson, BD | 1 |
| Aldinucci, C | 1 |
| Maiorca, SM | 1 |
| De Rosa, P | 1 |
| Palmi, M | 1 |
| Sticozzi, C | 1 |
| Ciccoli, L | 2 |
| Leoncini, S | 2 |
| Signorini, C | 2 |
| Pessina, GP | 1 |
| Thangarajah, H | 2 |
| Yao, D | 2 |
| Chang, EI | 2 |
| Shi, Y | 2 |
| Jazayeri, L | 1 |
| Vial, IN | 2 |
| Galiano, RD | 2 |
| Du, XL | 1 |
| Grogan, R | 1 |
| Galvez, MG | 2 |
| Januszyk, M | 2 |
| Brownlee, M | 2 |
| Gurtner, GC | 2 |
| Grogan, RH | 1 |
| Glotzbach, JP | 1 |
| Wong, VW | 1 |
| Leger, AJ | 1 |
| Altobelli, A | 1 |
| Mosquea, LM | 1 |
| Belanger, AJ | 1 |
| Song, A | 1 |
| Cheng, SH | 1 |
| Jiang, C | 1 |
| Yew, NS | 1 |
| Cook, RJ | 1 |
| Karch, C | 1 |
| Nahar, P | 1 |
| Rivera, A | 1 |
| Ko, JL | 1 |
| Zheng, KY | 1 |
| Guo, AJ | 1 |
| Bi, CW | 1 |
| Zhu, KY | 1 |
| Chan, GK | 1 |
| Fu, Q | 1 |
| Xu, SL | 1 |
| Zhan, JY | 1 |
| Lau, DT | 1 |
| Dong, TT | 1 |
| Choi, RC | 1 |
| Tsim, KW | 1 |
| Yuan, G | 1 |
| Khan, SA | 1 |
| Luo, W | 1 |
| Nanduri, J | 1 |
| Semenza, GL | 2 |
| Prabhakar, NR | 1 |
| Nevo-Caspi, Y | 1 |
| Amariglio, N | 1 |
| Rechavi, G | 1 |
| Paret, G | 1 |
| Wree, A | 1 |
| Mayer, A | 1 |
| Westphal, S | 1 |
| Beilfuss, A | 1 |
| Canbay, A | 1 |
| Schick, RR | 1 |
| Gerken, G | 1 |
| Vaupel, P | 1 |
| Quach, P | 1 |
| Gutierrez, E | 1 |
| Basha, MT | 1 |
| Kalinowski, DS | 1 |
| Sharpe, PC | 1 |
| Lovejoy, DB | 1 |
| Bernhardt, PV | 1 |
| Jansson, PJ | 1 |
| Richardson, DR | 1 |
| Bala, K | 1 |
| Gohil, NK | 1 |
| Wu, B | 1 |
| Teng, H | 1 |
| Yang, G | 1 |
| Wu, L | 1 |
| Wang, R | 1 |
| Chen, D | 1 |
| Zhou, Z | 1 |
| Xing, Y | 1 |
| Zhong, Y | 1 |
| Zou, X | 1 |
| Tian, W | 1 |
| Zhang, C | 1 |
| Chan, DA | 1 |
| Sutphin, PD | 1 |
| Denko, NC | 1 |
| Giaccia, AJ | 1 |
| Pham, I | 1 |
| Uchida, T | 2 |
| Planes, C | 1 |
| Ware, LB | 1 |
| Kaner, R | 1 |
| Matthay, MA | 2 |
| Clerici, C | 2 |
| Kitamuro, T | 1 |
| Takahashi, K | 1 |
| Ogawa, K | 1 |
| Udono-Fujimori, R | 1 |
| Furuyama, K | 1 |
| Nakayama, M | 1 |
| Sun, J | 1 |
| Fujita, H | 1 |
| Hida, W | 1 |
| Hattori, T | 1 |
| Shirato, K | 1 |
| Igarashi, K | 1 |
| Shibahara, S | 1 |
| Rossi, V | 1 |
| Paffetti, P | 1 |
| Bracci, R | 1 |
| Buonocore, G | 1 |
| Comporti, M | 1 |
| Jeong, HJ | 1 |
| Chung, HS | 1 |
| Lee, BR | 1 |
| Kim, SJ | 1 |
| Yoo, SJ | 1 |
| Hong, SH | 1 |
| Kim, HM | 1 |
| Coulet, F | 1 |
| Nadaud, S | 1 |
| Agrapart, M | 1 |
| Soubrier, F | 1 |
| Knerr, I | 1 |
| Weigel, C | 1 |
| Linnemann, K | 1 |
| Dötsch, J | 1 |
| Meissner, U | 1 |
| Fusch, C | 1 |
| Rascher, W | 1 |
| Ameri, K | 2 |
| Lewis, CE | 1 |
| Raida, M | 2 |
| Sowter, H | 1 |
| Hai, T | 2 |
| Harris, AL | 2 |
| Hofbauer, KH | 1 |
| Gess, B | 1 |
| Lohaus, C | 1 |
| Meyer, HE | 1 |
| Katschinski, D | 1 |
| Kurtz, A | 1 |
| Joung, YH | 1 |
| Park, JH | 1 |
| Park, T | 1 |
| Lee, CS | 1 |
| Kim, OH | 1 |
| Ye, SK | 1 |
| Yang, UM | 1 |
| Lee, KJ | 1 |
| Yang, YM | 1 |
| Pichiule, P | 1 |
| Chavez, JC | 1 |
| LaManna, JC | 1 |
| Rossignol, F | 1 |
| Mounier, R | 1 |
| Couette, S | 1 |
| Clottes, E | 1 |
| Salnikow, K | 1 |
| Li, X | 1 |
| Lippmann, M | 1 |
| Cuaz-Pérolin, C | 1 |
| Furman, C | 1 |
| Larigauderie, G | 1 |
| Legedz, L | 1 |
| Lasselin, C | 1 |
| Copin, C | 1 |
| Jaye, M | 1 |
| Searfoss, G | 1 |
| Yu, KT | 1 |
| Duverger, N | 1 |
| Nègre-Salvayre, A | 1 |
| Fruchart, JC | 1 |
| Rouis, M | 1 |
| Obach, M | 1 |
| Navarro-Sabaté, A | 1 |
| Caro, J | 2 |
| Kong, X | 1 |
| Duran, J | 1 |
| Gómez, M | 1 |
| Perales, JC | 1 |
| Ventura, F | 1 |
| Rosa, JL | 1 |
| Bartrons, R | 1 |
| Hamrick, SE | 1 |
| McQuillen, PS | 1 |
| Jiang, X | 1 |
| Mu, D | 1 |
| Madan, A | 1 |
| Ferriero, DM | 1 |
| Vengellur, A | 1 |
| Phillips, JM | 1 |
| Hogenesch, JB | 1 |
| LaPres, JJ | 1 |
| Pandolfi, S | 1 |
| Bonafè, M | 1 |
| Di Tella, L | 1 |
| Tiberi, L | 1 |
| Salvioli, S | 1 |
| Monti, D | 1 |
| Sorbi, S | 1 |
| Franceschi, C | 1 |
| Wentowska, K | 1 |
| Yeung, HY | 1 |
| Lai, KP | 1 |
| Chan, HY | 1 |
| Mak, NK | 1 |
| Wagner, GF | 1 |
| Wong, CK | 1 |
| Lee, KH | 1 |
| Choi, E | 1 |
| Chun, YS | 1 |
| Kim, MS | 1 |
| Park, JW | 2 |
| Krishnamurthy, P | 1 |
| Schuetz, JD | 1 |
| Callinan, L | 1 |
| McCarthy, TV | 1 |
| Maulet, Y | 1 |
| Mackrill, JJ | 1 |
| Resnik, E | 1 |
| Herron, J | 1 |
| Fu, R | 1 |
| Ivy, DD | 1 |
| Cornfield, DN | 1 |
| Danielisova, V | 1 |
| Woo, KJ | 1 |
| Lee, TJ | 1 |
| Kwon, TK | 1 |
| Kerendi, F | 1 |
| Kirshbom, PM | 1 |
| Halkos, ME | 1 |
| Wang, NP | 1 |
| Kin, H | 1 |
| Jiang, R | 1 |
| Zhao, ZQ | 1 |
| Kanter, KR | 1 |
| Guyton, RA | 1 |
| Vinten-Johansen, J | 1 |
| Hammond, EM | 1 |
| Culmsee, C | 1 |
| Katschinski, DM | 1 |
| Wenger, RH | 1 |
| Wagner, E | 1 |
| Davis, RJ | 1 |
| Denko, N | 1 |
| Kinderlerer, AR | 1 |
| Steinberg, R | 1 |
| Johns, M | 1 |
| Harten, SK | 1 |
| Lidington, EA | 1 |
| Haskard, DO | 1 |
| Maxwell, PH | 2 |
| Mason, JC | 1 |
| Thomas, R | 1 |
| Kim, MH | 1 |
| Nguyen, MV | 1 |
| Pouvreau, S | 1 |
| El Hajjaji, FZ | 1 |
| Denavit-Saubie, M | 1 |
| Pequignot, JM | 1 |
| Clavijo, C | 1 |
| Chen, JL | 1 |
| Kim, KJ | 1 |
| Reyland, ME | 1 |
| Ann, DK | 1 |
| Tracy, K | 1 |
| Dibling, BC | 1 |
| Spike, BT | 1 |
| Knabb, JR | 1 |
| Schumacker, P | 1 |
| Macleod, KF | 1 |
| Carabelli, V | 1 |
| Marcantoni, A | 1 |
| Comunanza, V | 1 |
| de Luca, A | 1 |
| Díaz, J | 1 |
| Borges, R | 1 |
| Carbone, E | 1 |
| Zhou, G | 1 |
| Dada, LA | 1 |
| Chandel, NS | 2 |
| Iwai, K | 1 |
| Lecuona, E | 1 |
| Ciechanover, A | 1 |
| Sznajder, JI | 1 |
| Dessouroux, A | 1 |
| Akwa, Y | 1 |
| Baulieu, EE | 1 |
| Kardashyan, L | 1 |
| Callaway, JK | 1 |
| Lee, EM | 1 |
| Beart, PM | 1 |
| Morita, K | 1 |
| Ihnken, K | 1 |
| Buckberg, GD | 1 |
| Sherman, MP | 1 |
| Young, HH | 1 |
| Ijichi, A | 1 |
| Sakuma, S | 1 |
| Tofilon, PJ | 1 |
| Ebert, BL | 1 |
| Broaddus, VC | 1 |
| Yang, L | 1 |
| Scavo, LM | 1 |
| Ernst, JD | 1 |
| Boylan, AM | 1 |
| Caraceni, P | 1 |
| De Maria, N | 1 |
| Ryu, HS | 1 |
| Colantoni, A | 1 |
| Roberts, L | 1 |
| Maidt, ML | 1 |
| Pye, Q | 1 |
| Bernardi, M | 1 |
| Van Thiel, DH | 1 |
| Floyd, RA | 1 |
| Lai, YL | 1 |
| Chiang, LY | 1 |
| Papadopoulos, MC | 1 |
| Koumenis, IL | 1 |
| Yuan, TY | 1 |
| Giffard, RG | 1 |
| Neumcke, I | 1 |
| Schneider, B | 1 |
| Fandrey, J | 1 |
| Pagel, H | 1 |
| Shadid, M | 1 |
| Van Bel, F | 1 |
| Steendijk, P | 1 |
| Dorrepaal, CA | 1 |
| Moison, R | 1 |
| Van Der Velde, ET | 1 |
| Baan, J | 1 |
| Saïag, B | 1 |
| Shacoori, V | 1 |
| Bodin, P | 1 |
| Pape, D | 1 |
| Allain, H | 1 |
| Burnstock, G | 1 |
| Riddle, SR | 1 |
| Ahmad, A | 1 |
| Ahmad, S | 1 |
| Deeb, SS | 1 |
| Malkki, M | 1 |
| Schneider, BK | 1 |
| Allen, CB | 1 |
| White, CW | 1 |
| McClintock, DS | 1 |
| Feliciano, CE | 1 |
| Wood, TM | 1 |
| Melendez, JA | 1 |
| Rodriguez, AM | 1 |
| Schumacker, PT | 1 |
| Ren, X | 1 |
| Ryter, SW | 1 |
| Si, M | 1 |
| Lai, CC | 1 |
| Su, CY | 1 |
| Norman, JT | 1 |
| Clark, IM | 1 |
| Garcia, PL | 1 |
| Dong, Z | 2 |
| Venkatachalam, MA | 2 |
| Wang, J | 1 |
| Patel, Y | 1 |
| Saikumar, P | 1 |
| Force, T | 1 |
| Nishiyama, J | 2 |
| Hung, TH | 1 |
| Skepper, JN | 1 |
| Burton, GJ | 1 |
| Seta, KA | 1 |
| Kim, R | 1 |
| Kim, HW | 1 |
| Millhorn, DE | 1 |
| Beitner-Johnson, D | 1 |
| Sang, N | 1 |
| Fang, J | 1 |
| Srinivas, V | 1 |
| Leshchinsky, I | 1 |
| De Marco, CS | 1 |
| Caniggia, I | 1 |
| Yi, X | 1 |
| Denton, M | 1 |
| Gu, S | 1 |
| Li, S | 1 |
| Qiang, M | 1 |
| Jacobsohn, E | 1 |
| Löwe, H | 1 |
| Voogd, A | 1 |
| Sluiter, W | 1 |
| van Eijk, HG | 2 |
| Koster, JF | 2 |
| Currin, RT | 1 |
| Gores, GJ | 1 |
| Thurman, RG | 1 |
| Lemasters, JJ | 1 |
| Shatos, MA | 1 |
| Doherty, JM | 1 |
| Stump, DC | 1 |
| Thompson, EA | 1 |
| Collen, D | 1 |
| van der Kraaij, AM | 1 |
| Mostert, LJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Endogenous Iron Status on Hypoxic Pulmonary Vascular Responses and Their Attenuation by Intravenous Iron[NCT01847352] | 31 participants (Actual) | Interventional | 2013-02-28 | Completed | |||
| Effects of Endogenous Iron Status and Intravenous Iron on Human Skeletal Muscle Metabolism at Rest and During Exercise[NCT02308449] | 29 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia (A Sub-Study)[NCT05349630] | Early Phase 1 | 5 participants (Anticipated) | Interventional | 2024-02-29 | Not yet recruiting | ||
| Impact of Hypoxia on Resting and Exertional Right Ventricular Performance - A PILOT STUDY[NCT05272514] | 10 participants (Actual) | Observational | 2022-04-15 | Completed | |||
| Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes[NCT03085771] | Phase 2 | 30 participants (Anticipated) | Interventional | 2017-01-01 | Recruiting | ||
| Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers[NCT03137966] | Phase 2 | 174 participants (Anticipated) | Interventional | 2022-12-30 | Not yet recruiting | ||
| Can Rhodiola Crenulata Intake Improve Oxygen Saturation and Decrease the Incidence of Acute Mountain Sickness.[NCT01536288] | Phase 2 | 125 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
| Strength Training in Hypoxia to Improve Bone and Cardiovascular Health of Elderly[NCT04281264] | 120 participants (Actual) | Interventional | 2019-02-09 | Completed | |||
| BIcarbonato di Sodio e N-Acetilcisteina Nella Prevenzione Della Nefropatia da Mezzo di Contrasto Nell'infaRto mIocardico acutO(Registro BINARIO)[NCT01218178] | 520 participants (Actual) | Observational | 2008-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for deferoxamine and Anoxemia
| Article | Year |
|---|---|
Advances in Hypoxia-Inducible Factor-1
Topics: Biocompatible Materials; Deferoxamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; I | 2023 |
Advances in Hypoxia-Inducible Factor-1
Topics: Biocompatible Materials; Deferoxamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; I | 2023 |
Advances in Hypoxia-Inducible Factor-1
Topics: Biocompatible Materials; Deferoxamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; I | 2023 |
Advances in Hypoxia-Inducible Factor-1
Topics: Biocompatible Materials; Deferoxamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; I | 2023 |
The ABC transporter Abcg2/Bcrp: role in hypoxia mediated survival.
Topics: Adenosine Triphosphate; Alleles; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; A | 2005 |
2 trials available for deferoxamine and Anoxemia
| Article | Year |
|---|---|
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
Topics: Adult; Blood Pressure; Cross-Over Studies; Deferoxamine; Erythropoietin; Female; Ferritins; Humans; | 2008 |
Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans.
Topics: Acute Disease; Adolescent; Adult; Carbon Dioxide; Carotid Body; Deferoxamine; Erythropoietin; Female | 2000 |
101 other studies available for deferoxamine and Anoxemia
| Article | Year |
|---|---|
Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway.
Topics: Animals; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Humans; Hypoxia; | 2012 |
Reciprocal role of PLAP-1 in HIF-1α-mediated responses to hypoxia.
Topics: Blotting, Western; Cell Hypoxia; Deferoxamine; Extracellular Matrix Proteins; Humans; Hypoxia; Hypox | 2022 |
The prolyl hydroxylase inhibitor GSK1120360A reduces early brain injury, but protection is not maintained in a neonatal rat model of hypoxic ischaemic encephalopathy.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Deferoxamine; Hypoxia; Hypoxia-Ischemia, Brain; Me | 2022 |
High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages.
Topics: Animals; Deferoxamine; Glucose; Hypoxia; Hypoxia-Inducible Factor 1; Macrophages; Magnesium Oxide; M | 2022 |
Activation of HIF-1α/VEGF-A pathway by deferoxamine ameliorates retinal hypoxia in a rat subarachnoid hemorrhage model.
Topics: Animals; Cell Adhesion Molecules; Deferoxamine; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; | 2022 |
Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders.
Topics: Acclimatization; Altitude; Altitude Sickness; Cerebrovascular Circulation; Deferoxamine; Ferric Comp | 2023 |
Metabolites from scutellarin alleviating deferoxamine-induced hypoxia injury in BV2 cells cultured on microfluidic chip combined with a mass spectrometer.
Topics: Cells, Cultured; Deferoxamine; Humans; Hypoxia; Mass Spectrometry; Microfluidics | 2023 |
A carbon dot-based fluorescent nanoprobe for the associated detection of iron ions and the determination of the fluctuation of ascorbic acid induced by hypoxia in cells and in vivo.
Topics: Animals; Ascorbic Acid; Carbon; Cell Hypoxia; Deferoxamine; Fluorescent Dyes; Hep G2 Cells; Humans; | 2019 |
Biodegradable hypoxia biomimicry microspheres for bone tissue regeneration.
Topics: Biomimetic Materials; Bone Regeneration; Deferoxamine; Drug Carriers; Drug Compounding; Drug Liberat | 2020 |
YC-1 sensitizes the antitumor effects of boron neutron capture therapy in hypoxic tumor cells.
Topics: Antineoplastic Agents; Boron Neutron Capture Therapy; Cell Hypoxia; Cell Line, Tumor; Cell Survival; | 2020 |
Topics: Animals; Bone Regeneration; Bone Substitutes; Calcium Phosphates; Deferoxamine; Hypoxia; Hypoxia-Ind | 2017 |
Hypoxia-inducible factor-1 in myocardial ischaemia/reperfusion injury.
Topics: Animals; Deferoxamine; Diabetes Mellitus, Experimental; Hypoxia; Hypoxia-Inducible Factor 1; Rats; S | 2017 |
Formation of spheroids by dental pulp cells in the presence of hypoxia and hypoxia mimetic agents.
Topics: Chemokine CXCL12; Deferoxamine; Dental Pulp; Enzyme-Linked Immunosorbent Assay; Glycine; Humans; Hyp | 2018 |
Deferoxamine preconditioning activated hypoxia-inducible factor-1α and MyD88-dependent Toll-like receptor 4 signaling in intestinal stem cells.
Topics: Animals; Cell Differentiation; Cells, Cultured; Deferoxamine; Hypoxia; Hypoxia-Inducible Factor 1, a | 2018 |
Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis.
Topics: Acetylation; Bone and Bones; Cell Line; Chromatin; Deferoxamine; Epigenesis, Genetic; Epigenomics; E | 2018 |
Hypoxia inducible factor-1α mediates iron uptake which induces inflammatory response in amoeboid microglial cells in developing periventricular white matter through MAP kinase pathway.
Topics: Animals; Cation Transport Proteins; Deferoxamine; Disulfides; Hypoxia; Hypoxia-Inducible Factor 1, a | 2014 |
Detailed assessment of gene activation levels by multiple hypoxia-responsive elements under various hypoxic conditions.
Topics: Animals; Cell Hypoxia; Colorectal Neoplasms; Deferoxamine; Fireflies; Gene Expression; HCT116 Cells; | 2014 |
Deferoxamine prevents cerebral glutathione and vitamin E depletions in asphyxiated neonatal rats: role of body temperature.
Topics: Animals; Animals, Newborn; Body Temperature; Brain; Deferoxamine; Female; Glutathione; Hyperthermia, | 2016 |
Deferoxamine improves antioxidative protection in the brain of neonatal rats: The role of anoxia and body temperature.
Topics: Animals; Animals, Newborn; Antioxidants; Body Temperature; Brain; Catalase; Deferoxamine; Female; Gl | 2016 |
Reference Genes for Addressing Gene Expression of Bladder Cancer Cell Models under Hypoxia: A Step Towards Transcriptomic Studies.
Topics: Actins; beta 2-Microglobulin; Cell Line, Tumor; Deferoxamine; Electron Transport Complex II; Gene Ex | 2016 |
Nitrite-derived nitric oxide reduces hypoxia-inducible factor 1α-mediated extracellular vesicle production by endothelial cells.
Topics: Allopurinol; Basic Helix-Loop-Helix Transcription Factors; Deferoxamine; Endothelial Cells; Enzyme I | 2017 |
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.
Topics: Amino Acids, Dicarboxylic; Cell Line; Deferoxamine; Gene Expression Profiling; Gene Expression Regul | 2008 |
Deferoxamine mimics the pattern of hypoxia-related injury at the microvasculature.
Topics: Animals; Capillary Permeability; Cell Adhesion; Cell Movement; Deferoxamine; Hypoxia; Leukocytes; Ma | 2009 |
Signaling and apoptosis differences between severe hypoxia and desferoxamine treatment of human epithelial cells.
Topics: Apoptosis; Cell Line; Deferoxamine; Enzyme Activation; Epithelial Cells; Glycogen Synthase Kinase 3; | 2008 |
Iron lung? New ideas about hypoxic pulmonary vasoconstriction.
Topics: Blood Pressure; Deferoxamine; Humans; Hypoxia; Iron; Pulmonary Artery; Pulmonary Circulation; Sidero | 2008 |
The effects of hypoxia/reoxygenation on the physiological behaviour of U373-MG astrocytes.
Topics: Adenosine Triphosphate; Astrocytes; Blotting, Western; Calcium; Cell Line; Cell Proliferation; Defer | 2010 |
The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues.
Topics: Animals; Cells, Cultured; Deferoxamine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus | 2009 |
HIF-1alpha dysfunction in diabetes.
Topics: Animals; Deferoxamine; Diabetes Mellitus; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit | 2010 |
Inhibition of osteoclastogenesis by prolyl hydroxylase inhibitor dimethyloxallyl glycine.
Topics: Animals; Cell Differentiation; Cell Line; Deferoxamine; Female; Gene Expression Regulation; Glycine; | 2010 |
Effects of desferoxamine-induced hypoxia on neuronal human mu-opioid receptor gene expression.
Topics: Cell Hypoxia; Cell Line, Tumor; Deferoxamine; Gene Expression; Gene Expression Regulation; Genes, Re | 2010 |
The extract of Rhodiolae Crenulatae Radix et Rhizoma induces the accumulation of HIF-1α via blocking the degradation pathway in cultured kidney fibroblasts.
Topics: Cells, Cultured; Deferoxamine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Erythropoiet | 2011 |
Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia.
Topics: Animals; Carotid Body; Central Nervous System; Deferoxamine; Digoxin; Enzyme Inhibitors; Fibroblasts | 2011 |
A-to-I RNA editing is induced upon hypoxia.
Topics: Adenosine; Cell Adhesion Molecules; Cell Line; Deferoxamine; Epigenesis, Genetic; Humans; Hypoxia; H | 2011 |
Adipokine expression in brown and white adipocytes in response to hypoxia.
Topics: Adipocytes, White; Adipokines; Adipose Tissue, Brown; Animals; Antimutagenic Agents; Cells, Cultured | 2012 |
Iron and iron regulatory proteins in amoeboid microglial cells are linked to oligodendrocyte death in hypoxic neonatal rat periventricular white matter through production of proinflammatory cytokines and reactive oxygen/nitrogen species.
Topics: Animals; Animals, Newborn; Cell Death; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Cytokin | 2011 |
Methemoglobin formation by triapine, di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone (Dp44mT), and other anticancer thiosemicarbazones: identification of novel thiosemicarbazones and therapeutics that prevent this effect.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Cell Proliferation; Deferoxamine; Drug Interactions; | 2012 |
Interaction of glycated protein and DFO mimicked hypoxia in cellular responses of HUVECs.
Topics: Deferoxamine; Dose-Response Relationship, Drug; Drug Combinations; Female; Gene Expression; Glycatio | 2012 |
Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α.
Topics: Amino Acids, Dicarboxylic; Cell Line; Cobalt; Deferoxamine; Down-Regulation; Eukaryotic Initiation F | 2012 |
Synergistic inhibition of Wnt pathway by HIF-1α and osteoblast-specific transcription factor osterix (Osx) in osteoblasts.
Topics: Cell Proliferation; Deferoxamine; HEK293 Cells; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha S | 2012 |
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha.
Topics: Amino Acids, Dicarboxylic; Animals; Chelating Agents; Cobalt; Deferoxamine; Fibroblasts; Hydroxylati | 2002 |
Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo.
Topics: Animals; Calcium Chloride; Cell Hypoxia; Cell Membrane Permeability; Cells, Cultured; Deferoxamine; | 2002 |
Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.
Topics: Animals; Basic-Leucine Zipper Transcription Factors; Blotting, Northern; Blotting, Western; Cattle; | 2003 |
Iron release in erythrocytes and plasma non protein-bound iron in hypoxic and non hypoxic newborns.
Topics: Adult; Blood Proteins; Case-Control Studies; Chelating Agents; Deferoxamine; Erythrocytes; Female; F | 2003 |
Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells.
Topics: Blotting, Western; Cell Line; Cell Nucleus; Cells, Cultured; Cytokines; Deferoxamine; Dose-Response | 2003 |
Identification of hypoxia-response element in the human endothelial nitric-oxide synthase gene promoter.
Topics: Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Deferoxamine; DNA-Bind | 2003 |
Transcriptional effects of hypoxia on fusiogenic syncytin and its receptor ASCT2 in human cytotrophoblast BeWo cells and in ex vivo perfused placental cotyledons.
Topics: Amino Acid Transport System ASC; Cell Line; Cobalt; Computer Systems; Deferoxamine; Down-Regulation; | 2003 |
Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells.
Topics: Activating Transcription Factor 4; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cobalt; Cystei | 2004 |
Oxygen tension regulates the expression of a group of procollagen hydroxylases.
Topics: Animals; Cells, Cultured; Cobalt; Deferoxamine; Electrophoresis, Gel, Two-Dimensional; Gene Expressi | 2003 |
Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells.
Topics: Animals; Caseins; Cell Line; Deferoxamine; DNA; DNA-Binding Proteins; Epithelial Cells; Gene Express | 2003 |
Hypoxic regulation of angiopoietin-2 expression in endothelial cells.
Topics: Angiopoietin-2; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cells, Cultured; C | 2004 |
Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha.
Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Nucleus; Cobalt; Deferoxamine; Dimeriz | 2004 |
Effect of nickel and iron co-exposure on human lung cells.
Topics: Air Pollutants; Blotting, Western; Carbon; Cell Cycle Proteins; Chlorides; Coal Ash; Deferoxamine; E | 2004 |
REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.
Topics: Adaptor Proteins, Signal Transducing; Arteriosclerosis; Cell Death; Cell Line; Cell Line, Tumor; Cel | 2004 |
6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia.
Topics: Animals; Binding Sites; Biotinylation; Blotting, Western; Cell Hypoxia; Cell Line; Cell Proliferatio | 2004 |
A role for hypoxia-inducible factor-1alpha in desferoxamine neuroprotection.
Topics: Analysis of Variance; Animals; Cell Count; Cell Death; Cell Hypoxia; Deferoxamine; Embryo, Mammalian | 2005 |
Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells.
Topics: Algorithms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cobalt; Deferoxamine; DNA Primers; Down-Reg | 2005 |
p66(shc) is highly expressed in fibroblasts from centenarians.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Aged; Aged, 80 and over; Apoptosis; Blottin | 2005 |
Perinatal asphyxia, hyperthermia and hyperferremia as factors inducing behavioural disturbances in adulthood: a rat model.
Topics: Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Attention Deficit and Disruptive Behavior | 2005 |
Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells.
Topics: Cell Line, Tumor; Colonic Neoplasms; Deferoxamine; Female; Ferric Compounds; Ferricyanides; Glycopro | 2005 |
Differential responses of two degradation domains of HIF-1alpha to hypoxia and iron deficiency.
Topics: Cell Line; Deferoxamine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Iron; Iron Defi | 2006 |
Atypical L-type channels are down-regulated in hypoxia.
Topics: Calcium Channels, L-Type; Cell Line, Tumor; Deferoxamine; Gene Expression Regulation; Humans; Hypoxi | 2005 |
Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits.
Topics: Animals; Calcium; Cells, Cultured; Deferoxamine; Fetus; Hypoxia; Immunohistochemistry; Intracellular | 2006 |
Effect of neonatal body temperature on postanoxic, potentially neurotoxic iron accumulation in the rat brain.
Topics: 3,3'-Diaminobenzidine; Analysis of Variance; Animals; Animals, Newborn; Body Temperature; Brain; Cel | 2006 |
Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway.
Topics: Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Deferoxamine; Ferric Compounds; Fl | 2006 |
Thoracic Surgery Directors Association Award. Cobalt chloride pretreatment attenuates myocardial apoptosis after hypothermic circulatory arrest.
Topics: Animals; Animals, Newborn; Apoptosis; Apoptosis Regulatory Proteins; Awards and Prizes; bcl-2-Associ | 2006 |
Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway.
Topics: Acetylcysteine; Activating Transcription Factor 3; Amino Acids, Dicarboxylic; Basic Helix-Loop-Helix | 2007 |
Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Atorvastatin; CD55 Antigens; CD59 Antigens; Cells, | 2006 |
Targeting the hypoxia inducible factor pathway with mitochondrial uncouplers.
Topics: Acetophenones; Basic Helix-Loop-Helix Transcription Factors; Benzopyrans; Carbonyl Cyanide p-Trifluo | 2007 |
Desferrioxamine enhances hypoxic ventilatory response and induces tyrosine hydroxylase gene expression in the rat brainstem in vivo.
Topics: Animals; Catecholamines; Deferoxamine; Gene Expression Regulation, Enzymologic; Hypoxia; Hypoxia-Ind | 2007 |
Protein kinase Cdelta-dependent and -independent signaling in genotoxic response to treatment of desferroxamine, a hypoxia-mimetic agent.
Topics: Active Transport, Cell Nucleus; Animals; Caspase 3; Cell Line; Deferoxamine; DNA Damage; Epithelial | 2007 |
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.
Topics: Animals; Autophagy; Base Sequence; Cell Death; Cells, Cultured; Deferoxamine; E2F Transcription Fact | 2007 |
Chronic hypoxia up-regulates alpha1H T-type channels and low-threshold catecholamine secretion in rat chromaffin cells.
Topics: Animals; Calcium; Calcium Channels, T-Type; Catecholamines; Cells, Cultured; Chromaffin Cells; Defer | 2007 |
Hypoxia-mediated Na-K-ATPase degradation requires von Hippel Lindau protein.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Membrane; Cells, Cultured; Chlorocebus a | 2008 |
DHEA decreases HIF-1alpha accumulation under hypoxia in human pulmonary artery cells: potential role in the treatment of pulmonary arterial hypertension.
Topics: Amino Acids, Dicarboxylic; Base Sequence; Cells, Cultured; Cobalt; Deferoxamine; Dehydroepiandroster | 2008 |
Long-term functional and protective actions of preconditioning with hypoxia, cobalt chloride, and desferrioxamine against hypoxic-ischemic injury in neonatal rats.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cobalt; Deferoxamine; Disease Models, Animal; Fe | 2008 |
Studies of hypoxemic/reoxygenation injury: without aortic clamping. IV. Role of the iron-catalyzed pathway: deferoxamine.
Topics: Alkadienes; Animals; Cardiopulmonary Bypass; Creatine Kinase; Deferoxamine; Heart; Hypoxia; Iron; Li | 1995 |
Hypoxia-induced vascular endothelial growth factor expression in normal rat astrocyte cultures.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Base Sequence; Benzoquinones; Bl | 1995 |
Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing.
Topics: Base Sequence; Biphenyl Compounds; Cobalt; Deferoxamine; DNA-Binding Proteins; Enhancer Elements, Ge | 1995 |
Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species.
Topics: Animals; Annexin A5; Apoptosis; Asbestos; Catalase; Cell Division; Cells, Cultured; Chelating Agents | 1996 |
Proteins but not nucleic acids are molecular targets for the free radical attack during reoxygenation of rat hepatocytes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deferoxamine; Deoxyguanosine; DNA; Free Radicals; Guanosine; H | 1997 |
Water-soluble fullerene derivatives attenuate exsanguination-induced bronchoconstriction of guinea-pigs.
Topics: Animals; Antidotes; Bronchoconstriction; Carbon; Deferoxamine; Endopeptidases; Expiratory Reserve Vo | 1997 |
Increasing vulnerability of astrocytes to oxidative injury with age despite constant antioxidant defenses.
Topics: Aging; Animals; Antioxidants; Astrocytes; Blotting, Western; Catalase; Deferoxamine; Glucose; Glutat | 1998 |
Effects of pro- and antioxidative compounds on renal production of erythropoietin.
Topics: Animals; Antioxidants; Chelating Agents; Deferoxamine; Erythropoietin; Free Radical Scavengers; Hydr | 1999 |
Effect of deferoxamine on post-hypoxic-ischemic reperfusion injury of the newborn lamb heart.
Topics: Animals; Animals, Newborn; Ascorbic Acid; Chelating Agents; Deferoxamine; Dehydroascorbic Acid; Fema | 1999 |
Free radical involvement in endothelium-dependent responses of the rat thoracic aorta in moderate hypoxic conditions.
Topics: Animals; Aorta, Thoracic; Benzophenones; Catalase; Chelating Agents; Deferoxamine; Diuretics, Osmoti | 1999 |
Hypoxia induces hexokinase II gene expression in human lung cell line A549.
Topics: Cell Line; Deferoxamine; DNA-Binding Proteins; Gene Expression; Hexokinase; Humans; Hypoxia; Hypoxia | 2000 |
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing.
Topics: Androstadienes; Animals; Cell Line; Cell Nucleus; Chelating Agents; Cobalt; Cytosol; Deferoxamine; D | 2000 |
Regulation of endothelial heme oxygenase activity during hypoxia is dependent on chelatable iron.
Topics: Acetylcysteine; Aminolevulinic Acid; Animals; Aorta, Thoracic; Carbon Monoxide; Cattle; Cell Hypoxia | 2000 |
Hypoxia promotes fibrogenesis in human renal fibroblasts.
Topics: Actins; Antimutagenic Agents; Cell Division; Cell Hypoxia; Cell Size; Cell Survival; Cells, Cultured | 2000 |
Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Antimutagenic Agents; Apoptosis; | 2001 |
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.
Topics: Aldehydes; Cyclic N-Oxides; Deferoxamine; Female; Fluorescent Antibody Technique; Heat-Shock Protein | 2001 |
Hypoxia-induced regulation of MAPK phosphatase-1 as identified by subtractive suppression hybridization and cDNA microarray analysis.
Topics: Animals; Blotting, Northern; Blotting, Western; Calcium; Cell Cycle Proteins; Cell Nucleus; Cobalt; | 2001 |
Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.
Topics: Adenovirus E1A Proteins; Aspartate Carbamoyltransferase; Blotting, Western; Carbamoyl-Phosphate Synt | 2002 |
Mechanisms of oxygen sensing in human trophoblast cells.
Topics: Adult; Chorionic Villi; Cobalt; Deferoxamine; Drug Combinations; Enzyme Inhibitors; Female; Ferrous | 2002 |
Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.
Topics: Cardiac Output; Deferoxamine; DNA-Binding Proteins; Echocardiography; Female; Heart Rate; Humans; Hy | 2002 |
Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.
Topics: Cardiac Output; Deferoxamine; DNA-Binding Proteins; Echocardiography; Female; Heart Rate; Humans; Hy | 2002 |
Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.
Topics: Cardiac Output; Deferoxamine; DNA-Binding Proteins; Echocardiography; Female; Heart Rate; Humans; Hy | 2002 |
Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.
Topics: Cardiac Output; Deferoxamine; DNA-Binding Proteins; Echocardiography; Female; Heart Rate; Humans; Hy | 2002 |
Gene promoter of apoptosis inhibitory protein IAP2: identification of enhancer elements and activation by severe hypoxia.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Cobalt; Cyclic AMP Response Element-Bi | 2002 |
Deferoxamine (Desferal) improves the content of oxygen in myocardial tissues during recovery after hypoxia in isolated rabbit heart.
Topics: Animals; Body Water; Copper; Deferoxamine; Heart; Hypoxia; In Vitro Techniques; Myocardium; Oxygen C | 1992 |
Low molecular weight iron and the oxygen paradox in isolated rat hearts.
Topics: Animals; Deferoxamine; Free Radicals; Hypoxia; In Vitro Techniques; Iron; Male; Molecular Weight; My | 1992 |
Protection by acidotic pH against anoxic cell killing in perfused rat liver: evidence for a pH paradox.
Topics: Animals; Antioxidants; Cell Survival; Deferoxamine; Hydrogen-Ion Concentration; Hypoxia; L-Lactate D | 1991 |
Oxygen radicals generated during anoxia followed by reoxygenation reduce the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in human endothelial cell culture.
Topics: Aerobiosis; Anaerobiosis; Cells, Cultured; Deferoxamine; Endothelium, Vascular; Free Radical Scaveng | 1990 |
Iron-load increases the susceptibility of rat hearts to oxygen reperfusion damage. Protection by the antioxidant (+)-cyanidanol-3 and deferoxamine.
Topics: Animals; Antioxidants; Cardiomyopathies; Catechin; Coronary Circulation; Deferoxamine; Disease Susce | 1988 |