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deferoxamine and Anemias, Iron-Deficiency

deferoxamine has been researched along with Anemias, Iron-Deficiency in 19 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
" Further, there is lack of agreement about the benefits of deferoxamine (Dfx) in the treatment of anemia and oxidative stress during inflammation and chronic diseases."3.69Iron metabolism and oxidative stress during acute and chronic phases of experimental inflammation: effect of iron-dextran and deferoxamine. ( Mitjavila, MT; Muntané, J; Puig-Parellada, P, 1995)
"Background Thrombocytopenia is common in sick neonates."1.46Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain barrier and impairs iron-dependent hippocampal neuron dendrite development. ( Bastian, TW; Chen, MJ; Connor, JR; Duck, KA; Georgieff, MK; Lanier, LM; Liu, ZJ; Michalopoulos, GC; Sola-Visner, MC, 2017)
"Iron deficiency and visceral leishmaniasis are serious problems of public health."1.37Leishmania chagasi: effect of the iron deficiency on the infection in BALB/c mice. ( Malafaia, G; Marcon, Lde N; Pedrosa, ML; Pereira, Lde F; Rezende, SA, 2011)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's4 (21.05)18.2507
2000's7 (36.84)29.6817
2010's5 (26.32)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Pietra, V1
Degrassi, S1
Fusi-Schmidhauser, T1
Zhdanov, VV1
Udut, EV1
Sotnikova, LS1
Burmina, YV1
Miroshnichenko, LA1
Simanina, EV1
Polyakova, TY1
Zyuz'kov, GN1
Chaikovskii, AV1
Stavrova, LA1
Fedorova, EP1
Dygai, AM1
Usende, IL1
Leitner, DF1
Neely, E1
Connor, JR2
Olopade, JO1
Bastian, TW1
Duck, KA1
Michalopoulos, GC1
Chen, MJ1
Liu, ZJ1
Lanier, LM1
Sola-Visner, MC1
Georgieff, MK1
Lakhal, S1
Talbot, NP1
Crosby, A1
Stoepker, C1
Townsend, AR1
Robbins, PA1
Pugh, CW1
Ratcliffe, PJ1
Mole, DR1
Malafaia, G1
Marcon, Lde N1
Pereira, Lde F1
Pedrosa, ML1
Rezende, SA1
Zhao, GY1
Zhao, LP1
He, YF1
Li, GF1
Gao, C1
Li, K1
Xu, YJ1
Kuvibidila, SR2
Porretta, C1
De, BK1
Roberts, WL1
Fidler, MC1
Davidsson, L1
Walczyk, T1
Hurrell, RF1
RICHMOND, J1
FIELDING, J1
Wood, DM1
Thomson, AH1
Lawes, M1
Jones, AL1
Dargan, PI1
Nurtjahja-Tjendraputra, E1
Fu, D1
Phang, JM1
Richardson, DR1
Muntané, J1
Puig-Parellada, P1
Mitjavila, MT1
Reynolds, T1
Mirfattahi, M1
Lomas, G1
Sajedianfard, J1
Boroujeni, HM1
Habibzadeh, F1
Kitchens, D1
Baliga, BS1
Huang, JY1
Wu, MS1
Wu, CH1

Trials

2 trials available for deferoxamine and Anemias, Iron-Deficiency

ArticleYear
Regulation of growth differentiation factor 15 expression by intracellular iron.
    Blood, 2009, Feb-12, Volume: 113, Issue:7

    Topics: Adenocarcinoma; Anemia, Iron-Deficiency; Basic Helix-Loop-Helix Transcription Factors; Breast Neopla

2009
Iron absorption from fish sauce and soy sauce fortified with sodium iron EDTA.
    The American journal of clinical nutrition, 2003, Volume: 78, Issue:2

    Topics: Adult; Anemia, Iron-Deficiency; Biological Availability; Deferoxamine; Diet; Edetic Acid; Female; Fe

2003

Other Studies

17 other studies available for deferoxamine and Anemias, Iron-Deficiency

ArticleYear
The Dark Side of Iron.
    The American journal of medicine, 2020, Volume: 133, Issue:1

    Topics: Acidosis; Adolescent; Anemia, Iron-Deficiency; Deferoxamine; Drug Overdose; Female; Ferrous Compound

2020
Pathogenetic Evaluation of Dysfunction in the Erythron System of Experimental Animals during Modeling of Iron Deficiency Anemia in the Gestation Period.
    Bulletin of experimental biology and medicine, 2016, Volume: 160, Issue:4

    Topics: Anemia, Iron-Deficiency; Animals; Blood Cell Count; Bone Marrow; Deferoxamine; Erythrocytes; Erythro

2016
The Deterioration Seen in Myelin Related Morphophysiology in Vanadium Exposed Rats is Partially Protected by Concurrent Iron Deficiency.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2016, Aug-30, Volume: 31, Issue:1

    Topics: Anemia, Iron-Deficiency; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Deferoxamine; Femal

2016
Eltrombopag, a thrombopoietin mimetic, crosses the blood-brain barrier and impairs iron-dependent hippocampal neuron dendrite development.
    Journal of thrombosis and haemostasis : JTH, 2017, Volume: 15, Issue:3

    Topics: Anemia, Iron-Deficiency; Animals; Benzoates; Biological Transport; Biomimetics; Blood-Brain Barrier;

2017
Leishmania chagasi: effect of the iron deficiency on the infection in BALB/c mice.
    Experimental parasitology, 2011, Volume: 127, Issue:3

    Topics: Anemia, Iron-Deficiency; Animals; Cytokines; Deferoxamine; Female; Hemoglobins; Leishmania infantum;

2011
A comparison of the biological activities of human osteoblast hFOB1.19 between iron excess and iron deficiency.
    Biological trace element research, 2012, Volume: 150, Issue:1-3

    Topics: Alkaline Phosphatase; Anemia, Iron-Deficiency; Apoptosis; Calcification, Physiologic; Cell Line; Cel

2012
Differential effects of iron deficiency on the expression of CD80 and CD86 co-stimulatory receptors in mitogen-treated and untreated murine spleen cells.
    Journal of cellular biochemistry, 2002, Volume: 86, Issue:3

    Topics: Anemia, Iron-Deficiency; Animals; Antigens, CD; B7-1 Antigen; B7-2 Antigen; Biomarkers; Cell Divisio

2002
Performance characteristics of the Dimension RxL iron and total iron-binding capacity methods.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Jul-01, Volume: 333, Issue:1

    Topics: Anemia, Iron-Deficiency; Deferoxamine; Drug Overdose; Hemoglobins; Humans; Iron; Iron Chelating Agen

2003
IRON DEFICIENCY ANAEMIA.
    The British journal of clinical practice, 1964, Volume: 18

    Topics: Anemia; Anemia, Hypochromic; Anemia, Iron-Deficiency; Deferoxamine; Drug Therapy; Hematologic Diseas

1964
DIFFERENTIAL FERRIOXAMINE TEST FOR MEASURING CHELATABLE BODY IRON.
    Journal of clinical pathology, 1965, Volume: 18

    Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Iron-Deficiency; Anemia, Pernicious; Deferoxami

1965
Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:4

    Topics: Anemia, Iron-Deficiency; Chemical and Drug Induced Liver Injury; Child, Preschool; Deferoxamine; Fer

2005
Iron chelation regulates cyclin D1 expression via the proteasome: a link to iron deficiency-mediated growth suppression.
    Blood, 2007, May-01, Volume: 109, Issue:9

    Topics: Anemia, Iron-Deficiency; Animals; Cell Cycle; Cell Line, Tumor; Deferoxamine; G1 Phase; Half-Life; H

2007
Iron metabolism and oxidative stress during acute and chronic phases of experimental inflammation: effect of iron-dextran and deferoxamine.
    The Journal of laboratory and clinical medicine, 1995, Volume: 126, Issue:5

    Topics: Acute Disease; Anemia, Iron-Deficiency; Animals; Carrageenan; Chronic Disease; Deferoxamine; Disease

1995
Desferrioxamine infusion due to heparin interference with iron assay. A paediatric problem.
    Clinica chimica acta; international journal of clinical chemistry, 1997, May-28, Volume: 261, Issue:2

    Topics: Adolescent; Anemia, Iron-Deficiency; Blood Specimen Collection; Child, Preschool; Deferoxamine; Fail

1997
Therapeutic values of different routes of administration of vitamin A with ferrous sulfate in treating deferoxamin-induced iron-deficiency anemia.
    Journal of nutritional science and vitaminology, 1999, Volume: 45, Issue:1

    Topics: Administration, Oral; Anemia, Iron-Deficiency; Animals; Deferoxamine; Ferrous Compounds; Injections,

1999
In vivo and in vitro iron deficiency reduces protein kinase C activity and translocation in murine splenic and purified T cells.
    Journal of cellular biochemistry, 1999, Sep-01, Volume: 74, Issue:3

    Topics: Anemia, Iron-Deficiency; Animals; Body Weight; CD3 Complex; Cell Division; Cell Membrane; Cells, Cul

1999
The effect of an iron supplement on serum aluminum level and desferrioxamine mobilization test in hemodialysis patients.
    Renal failure, 2001, Volume: 23, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aluminum; Anemia, Iron-Deficiency; Deferoxamine; Female; Ferritins;

2001