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deferoxamine and Anemia With Multinucleated Erythroblasts

deferoxamine has been researched along with Anemia With Multinucleated Erythroblasts in 11 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Research Excerpts

ExcerptRelevanceReference
"Deferoxamine was given subcutaneously for 14 months."5.26Use of subcutaneous deferoxamine in a child with hemochromatosis associated with congenital dyserythropoietic anemia, type I. ( Perrault, J; Smithson, WA, 1982)
"Iron overload was a frequent complication."2.42Congenital dyserythropoietic anemia type II: epidemiology, clinical appearance, and prognosis based on long-term observation. ( Anselstetter, V; Chrobak, L; Denecke, J; Einsiedler, B; Gallmeier, K; Griesshammer, A; Heimpel, H; Janka-Schaub, G; Kohne, E; Kron, M; Marquardt, T, 2003)
"Deferoxamine was given subcutaneously for 14 months."1.26Use of subcutaneous deferoxamine in a child with hemochromatosis associated with congenital dyserythropoietic anemia, type I. ( Perrault, J; Smithson, WA, 1982)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's5 (45.45)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergmann, AK1
Tamary, H1
Neufeld, EJ1
Cario, H1
Grosse, R1
Janssen, G1
Jarisch, A1
Meerpohl, J1
Strauss, G1
Buchbinder, D1
Nugent, D1
Vu, D1
Soni, A1
Stites, J1
Hsieh, L1
Puthenveetil, G1
Heimpel, H1
Anselstetter, V1
Chrobak, L1
Denecke, J1
Einsiedler, B1
Gallmeier, K1
Griesshammer, A1
Marquardt, T1
Janka-Schaub, G1
Kron, M1
Kohne, E1
Smithson, WA1
Perrault, J1
Adams, DM1
Schultz, WH1
Ware, RE1
Kinney, TR1
Galacteros, F1
Schmitt, K1
Tulzer, W1
Prasher, N1
Prasher, BS1
Cacciola, E1
Miyazawa, K1
Yoshikawa, O1
Takakuwa, Y1
Tuda, A1
Ohtaka, M1
Lin, KY1
Iguchi, Y1
Naruto, M1
Kondo, M1
Toyama, K1

Reviews

3 reviews available for deferoxamine and Anemia With Multinucleated Erythroblasts

ArticleYear
Congenital dyserythropoietic anemia type II: epidemiology, clinical appearance, and prognosis based on long-term observation.
    Blood, 2003, Dec-15, Volume: 102, Issue:13

    Topics: Adolescent; Adult; Aged; Anemia, Dyserythropoietic, Congenital; Child; Child, Preschool; Cholelithia

2003
[Secondary iron overload].
    Annales de biologie clinique, 1998, Volume: 56 Spec No

    Topics: Adult; Anemia, Dyserythropoietic, Congenital; Anemia, Hemolytic; Bone Marrow Examination; Chelating

1998
[Successful treatment of congenital dyserythropoietic anemia type I with long-term administration of deferoxamine].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1988, Volume: 29, Issue:9

    Topics: Adult; Anemia, Dyserythropoietic, Congenital; Anemia, Hemolytic, Congenital; Deferoxamine; Drug Eval

1988

Other Studies

8 other studies available for deferoxamine and Anemia With Multinucleated Erythroblasts

ArticleYear
Remission from transfusion-dependence in a patient with congenital dyserythropoietic anemia (CDA) and increased intensity of iron chelation.
    Pediatric blood & cancer, 2009, Volume: 53, Issue:6

    Topics: Adolescent; Anemia, Dyserythropoietic, Congenital; Blood Transfusion; Deferoxamine; Erythropoiesis;

2009
[Guidelines for diagnosis and treatment of secondary iron overload in patients with congenital anemia].
    Klinische Padiatrie, 2010, Volume: 222, Issue:6

    Topics: Anemia, Aplastic; Anemia, Diamond-Blackfan; Anemia, Dyserythropoietic, Congenital; Anemia, Sickle Ce

2010
Unrelated hematopoietic stem cell transplantation in a patient with congenital dyserythropoietic anemia and iron overload.
    Pediatric transplantation, 2012, Volume: 16, Issue:3

    Topics: Anemia, Dyserythropoietic, Congenital; Benzoates; Bone Marrow Transplantation; Child, Preschool; Def

2012
Use of subcutaneous deferoxamine in a child with hemochromatosis associated with congenital dyserythropoietic anemia, type I.
    Mayo Clinic proceedings, 1982, Volume: 57, Issue:5

    Topics: Anemia, Dyserythropoietic, Congenital; Anemia, Hemolytic, Congenital; Biopsy; Child; Deferoxamine; F

1982
Erythrocytapheresis can reduce iron overload and prevent the need for chelation therapy in chronically transfused pediatric patients.
    Journal of pediatric hematology/oncology, 1996, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Anemia, Dyserythropoietic, Congenital; Anemia, Sickle Cell; Chelation Therapy; Ch

1996
[Rare indications for iron chelation therapy with desferrioxamine].
    Padiatrie und Padologie, 1991, Volume: 26, Issue:4

    Topics: Adolescent; Anemia, Dyserythropoietic, Congenital; Chelation Therapy; Deferoxamine; Dose-Response Re

1991
Congenital dyserythropoietic anaemia.
    The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:11

    Topics: Anemia, Dyserythropoietic, Congenital; Deferoxamine; Female; Humans

1990
[Dyserythropoietic syndromes: incidence, diagnosis, therapy].
    Recenti progressi in medicina, 1990, Volume: 81, Issue:10

    Topics: Anemia, Dyserythropoietic, Congenital; Anemia, Refractory; Anemia, Sideroblastic; Deferoxamine; Diag

1990