deferoxamine has been researched along with Anemia, Refractory in 9 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Anemia, Refractory: A severe sometimes chronic anemia, usually macrocytic in type, that does not respond to ordinary antianemic therapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine (2g/day) was given intravenously by continuous infusion." | 5.29 | [Successful treatment with deferoxamine in a case of refractory anemia]. ( Ishiyama, T; Kawakami, K; Onizuka, T; Tomoyasu, S; Tsuruoka, N, 1993) |
| "Deferoxamine (2g/day) was given intravenously by continuous infusion." | 1.29 | [Successful treatment with deferoxamine in a case of refractory anemia]. ( Ishiyama, T; Kawakami, K; Onizuka, T; Tomoyasu, S; Tsuruoka, N, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tazmini, K | 1 |
| Bakken, HN | 1 |
| Schjesvold, FH | 1 |
| Kubota, N | 1 |
| Miyazawa, K | 1 |
| Shoji, N | 1 |
| Sumi, M | 1 |
| Nakajima, A | 1 |
| Kimura, Y | 1 |
| Oshiro, H | 1 |
| Ebihara, Y | 1 |
| Ohyashiki, K | 1 |
| González, FA | 1 |
| Arrizabalaga, B | 1 |
| Villegas, A | 1 |
| Alonso, D | 1 |
| Castro, M | 1 |
| Remacha, A | 1 |
| del Arco, A | 1 |
| Martín Núñez, G | 1 |
| Keijzer, A | 1 |
| van der Valk, P | 1 |
| Ossenkoppele, GJ | 1 |
| van de Loosdrecht, AA | 1 |
| Lewinski, UH | 1 |
| Floru, S | 1 |
| Cohen, AM | 1 |
| Mittelmann, M | 1 |
| Mehta, AM | 1 |
| Engstrom, RE | 1 |
| Kreiger, AE | 1 |
| Tomoyasu, S | 1 |
| Kawakami, K | 1 |
| Onizuka, T | 1 |
| Ishiyama, T | 1 |
| Tsuruoka, N | 1 |
| Sivakumaran, M | 1 |
| Hudson, P | 1 |
| Cacciola, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Pharmacodynamic Correlate Trial of Sirolimus in Combination With Chemotherapy (Idarubicin, Cytarabine) for the Treatment of Newly Diagnosed Acute Myelogenous Leukemia[NCT01822015] | Early Phase 1 | 55 participants (Actual) | Interventional | 2013-03-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for deferoxamine and Anemia, Refractory
| Article | Year |
|---|---|
A woman in her seventies with reduced general condition, dyspnoea and generalised pain.
Topics: Aged; Anemia, Refractory; Anemia, Sideroblastic; Chelation Therapy; Deferoxamine; Diagnosis, Differe | 2012 |
A massive intraventricular thrombosis by disseminated mucormycosis in a patient with myelodysplastic syndrome during deferoxamine therapy.
Topics: Aged; Anemia, Refractory; Deferoxamine; Echocardiography; Fatal Outcome; Heart Diseases; Heart Ventr | 2003 |
[Study of deferoxamine in subcutaneous profusion treatment of iron overload in myelodysplastic syndromes].
Topics: Aged; Anemia, Refractory; Anemia, Sideroblastic; Blood Transfusion; Deferoxamine; Female; Ferritins; | 2005 |
Mucormycosis in a patient with low risk myelodysplasia treated with anti-TNF-alpha.
Topics: Anemia, Refractory; Anemia, Sideroblastic; Antibodies, Monoclonal; Apoptosis; Combined Modality Ther | 2006 |
Recombinant human erythropoietin in the treatment of myelodysplastic syndromes--response patterns.
Topics: Aged; Aged, 80 and over; Anemia, Refractory; Anemia, Sideroblastic; Blood Transfusion; Chelation The | 1994 |
Deferoxamine-associated retinopathy after subcutaneous injection.
Topics: Aged; Anemia, Refractory; Color Vision Defects; Deferoxamine; Female; Fluorescein Angiography; Fundu | 1994 |
[Successful treatment with deferoxamine in a case of refractory anemia].
Topics: Anemia, Refractory; Deferoxamine; Female; Humans; Infusions, Intravenous; Middle Aged | 1993 |
Blood and blisters: porphyria cutanea tarda in myelodysplastic syndrome.
Topics: Aged; Aged, 80 and over; Anemia, Refractory; Deferoxamine; Female; Hand Dermatoses; Humans; Iron Che | 2002 |
[Dyserythropoietic syndromes: incidence, diagnosis, therapy].
Topics: Anemia, Dyserythropoietic, Congenital; Anemia, Refractory; Anemia, Sideroblastic; Deferoxamine; Diag | 1990 |