deferoxamine has been researched along with Anaplastic Astrocytoma in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Deferoxamine (DFO) caused decreased viability of human neuronal tumor cells (SK-N-MC neuroblastoma and U-373 MG astrocytoma) in a dose-dependent manner." | 3.69 | Deferoxamine-induced cytotoxicity in human neuronal cell lines: protection by free radical scavengers. ( Lee, YS; Wurster, RD, 1995) |
| "Deferoxamine is an effective iron chelator and a potential therapeutic agent for use in minimizing free radical-mediated injury following trauma." | 1.30 | Screening of transcriptionally regulated genes following iron chelation in human astrocytoma cells. ( Connor, JR; Ye, Z, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Imaizumi, T | 1 |
| Sakashita, N | 1 |
| Mushiga, Y | 1 |
| Yoshida, H | 1 |
| Hayakari, R | 1 |
| Xing, F | 1 |
| Wang, L | 1 |
| Matsumiya, T | 1 |
| Tanji, K | 1 |
| Chiba, Y | 1 |
| Furudate, K | 1 |
| Kawaguchi, S | 1 |
| Murakami, M | 1 |
| Tanaka, H | 1 |
| Shimizu, T | 1 |
| Uehara, T | 1 |
| Nomura, Y | 1 |
| Lee, YS | 1 |
| Wurster, RD | 1 |
| Ye, Z | 1 |
| Connor, JR | 1 |
4 other studies available for deferoxamine and Anaplastic Astrocytoma
| Article | Year |
|---|---|
Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.
Topics: Astrocytoma; Cell Line, Tumor; Chemokine CXCL10; Deferoxamine; Dose-Response Relationship, Drug; Dru | 2015 |
Possible involvement of pyruvate kinase in acquisition of tolerance to hypoxic stress in glial cells.
Topics: Antimutagenic Agents; Apoptosis; Astrocytoma; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cel | 2004 |
Deferoxamine-induced cytotoxicity in human neuronal cell lines: protection by free radical scavengers.
Topics: Analysis of Variance; Antioxidants; Astrocytoma; Calcium Channel Blockers; Cell Survival; Deferoxami | 1995 |
Screening of transcriptionally regulated genes following iron chelation in human astrocytoma cells.
Topics: Astrocytoma; Brain Neoplasms; Chelating Agents; Deferoxamine; Gene Expression Regulation, Neoplastic | 1999 |