deferoxamine has been researched along with Altitude Sickness in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Altitude Sickness: Multiple symptoms associated with reduced oxygen at high ALTITUDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The onset of tissue hypoxemia coincides with the stabilization of hypoxia-inducible factor (HIF) and transcription of downstream HIF-mediated processes." | 1.91 | Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders. ( Ainslie, PN; Anholm, JD; Gasho, C; Hoiland, RL; Patrician, A; Subedi, P; Tymko, MM; Willie, C, 2023) |
| "High altitude cerebral edema (HACE) is a fulminant, deadly, and yet still unpredictable brain disease." | 1.43 | Preventing High Altitude Cerebral Edema in Rats with Repurposed Anti-Angiogenesis Pharmacotherapy. ( Irwin, DC; Loomis, Z; Maltzahn, J; Tarshis, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patrician, A | 1 |
| Willie, C | 1 |
| Hoiland, RL | 1 |
| Gasho, C | 1 |
| Subedi, P | 1 |
| Anholm, JD | 1 |
| Tymko, MM | 1 |
| Ainslie, PN | 1 |
| Tarshis, S | 1 |
| Maltzahn, J | 1 |
| Loomis, Z | 1 |
| Irwin, DC | 1 |
2 other studies available for deferoxamine and Altitude Sickness
| Article | Year |
|---|---|
Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders.
Topics: Acclimatization; Altitude; Altitude Sickness; Cerebrovascular Circulation; Deferoxamine; Ferric Comp | 2023 |
Preventing High Altitude Cerebral Edema in Rats with Repurposed Anti-Angiogenesis Pharmacotherapy.
Topics: Acetazolamide; Altitude; Altitude Sickness; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; A | 2016 |