deferoxamine has been researched along with Allergic Encephalomyelitis in 5 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Induction of experimental allergic encephalomyelitis (EAE) in Lewis rats by injection of guinea pig (GP) spinal cord homogenate (SCH) plus adjuvant (SCH-CFA) can be inhibited by treatment with the iron chelating agent desferrioxamine (DFOM)." | 1.27 | Inhibition of allergic encephalomyelitis by the iron chelating agent desferrioxamine: differential effect depending on type of sensitizing encephalitogen. ( Bowern, NA; Danta, G; Doherty, PC; Willenborg, DO, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowern, N | 1 |
| Ramshaw, IA | 1 |
| Clark, IA | 1 |
| Doherty, PC | 2 |
| Guy, J | 1 |
| McGorray, S | 1 |
| Qi, X | 1 |
| Fitzsimmons, J | 1 |
| Mancuso, A | 1 |
| Rao, N | 1 |
| Pedchenko, TV | 1 |
| LeVine, SM | 1 |
| Willenborg, DO | 1 |
| Bowern, NA | 1 |
| Danta, G | 1 |
| O'Brien, JT | 1 |
| Noseworthy, JH | 1 |
| Gilbert, JJ | 1 |
| Karlik, SJ | 1 |
5 other studies available for deferoxamine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Inhibition of autoimmune neuropathological process by treatment with an iron-chelating agent.
Topics: Animals; Autoimmune Diseases; Blood Coagulation Tests; Chelating Agents; Deferoxamine; Encephalomyel | 1984 |
Conjugated deferoxamine reduces blood-brain barrier disruption in experimental optic neuritis.
Topics: Animals; Blood-Brain Barrier; Capillary Permeability; Deferoxamine; Disease Models, Animal; Encephal | 1994 |
Desferrioxamine suppresses experimental allergic encephalomyelitis induced by MBP in SJL mice.
Topics: Animals; Deferoxamine; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Ferric C | 1998 |
Inhibition of allergic encephalomyelitis by the iron chelating agent desferrioxamine: differential effect depending on type of sensitizing encephalitogen.
Topics: Animals; Deferoxamine; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Immunizatio | 1988 |
NMR changes in experimental allergic encephalomyelitis: NMR changes precede clinical and pathological events.
Topics: Animals; Blood-Brain Barrier; Brain; Contrast Media; Deferoxamine; Encephalomyelitis, Autoimmune, Ex | 1987 |