deferoxamine has been researched along with Adjuvant Arthritis in 4 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we evaluated RAc1 nano particle effects on hyperalgesia and liver hepcidin and serum IL-1β and TNF-α expression levels during acute and chronic phases of adjuvant-induced inflammation in male rats and compared its effects with Deferoxamine." | 3.91 | Anti-hyperalgesia effect of nanchelating based nano particle, RAc1, can be mediated via liver hepcidin expression modulation during persistent inflammation. ( Houshmandi, E; Kalanaky, S; Manaheji, H; Mirjafai, S; Mohammadi, M; Nazemian, V; Zaringhalam, J, 2019) |
| "In this paper we studied the modulating inflammatory activity of iron in the adjuvant arthritis, taking indomethacin as a standard antiinflammatory drug and a superoxide dismutase derivative (MPEG-SOD) as a scavenger of free radicals." | 3.68 | Desferrioxamine potentiated SOD antiinflammatory activity in rat adjuvant arthritis: role of iron and bacterial toxins. ( Benoni, G; Caliceti, P; Caramazza, I; Conforti, A; Cuzzolin, L; Del Soldato, P; Zambreri, D, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nazemian, V | 1 |
| Kalanaky, S | 1 |
| Manaheji, H | 1 |
| Houshmandi, E | 1 |
| Mohammadi, M | 1 |
| Zaringhalam, J | 1 |
| Mirjafai, S | 1 |
| Benoni, G | 1 |
| Cuzzolin, L | 1 |
| Zambreri, D | 1 |
| Caramazza, I | 1 |
| Del Soldato, P | 1 |
| Caliceti, P | 1 |
| Conforti, A | 1 |
| Hirschelmann, R | 1 |
| Bekemeier, H | 1 |
| Andrews, FJ | 1 |
| Morris, CJ | 1 |
| Kondratowicz, G | 1 |
| Blake, DR | 1 |
4 other studies available for deferoxamine and Adjuvant Arthritis
| Article | Year |
|---|---|
Anti-hyperalgesia effect of nanchelating based nano particle, RAc1, can be mediated via liver hepcidin expression modulation during persistent inflammation.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Deferoxamine; Hepcidins; Humans; Hyperalges | 2019 |
Desferrioxamine potentiated SOD antiinflammatory activity in rat adjuvant arthritis: role of iron and bacterial toxins.
Topics: Animals; Arthritis, Experimental; Clostridium perfringens; Deferoxamine; Drug Synergism; Feces; Free | 1992 |
Influence of the iron chelating agent desferrioxamine on two rat inflammatory models.
Topics: Animals; Arthritis, Experimental; Carrageenan; Deferoxamine; Edema; Inflammation; Rats; Rats, Inbred | 1986 |
Effect of iron chelation on inflammatory joint disease.
Topics: Animals; Arthritis; Arthritis, Experimental; Deferoxamine; Liver; Lymph Nodes; Male; Orosomucoid; Ra | 1987 |