Page last updated: 2024-10-25

deferoxamine and Acute-Phase Reaction

deferoxamine has been researched along with Acute-Phase Reaction in 2 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Acute-Phase Reaction: An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma.

Research Excerpts

ExcerptRelevanceReference
"Deferoxamine is still today the only preventive and curative treatment of transfusional hemochromatosis."3.68[Intensifying iron chelating therapy with desferrioxamine using implantable venous access catheters (Port-A-Cath)]. ( Clairicia, M; de Montalembert, M; Girot, R; Hannedouche, T; Jan, D; Sidi, D, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hod, EA1
Zhang, N1
Sokol, SA1
Wojczyk, BS1
Francis, RO1
Ansaldi, D1
Francis, KP1
Della-Latta, P1
Whittier, S1
Sheth, S1
Hendrickson, JE1
Zimring, JC1
Brittenham, GM1
Spitalnik, SL1
de Montalembert, M1
Jan, D1
Clairicia, M1
Hannedouche, T1
Sidi, D1
Girot, R1

Other Studies

2 other studies available for deferoxamine and Acute-Phase Reaction

ArticleYear
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation.
    Blood, 2010, May-27, Volume: 115, Issue:21

    Topics: Acute-Phase Reaction; Animals; Blood Preservation; Deferoxamine; Disease Models, Animal; Endotoxemia

2010
[Intensifying iron chelating therapy with desferrioxamine using implantable venous access catheters (Port-A-Cath)].
    Archives francaises de pediatrie, 1992, Volume: 49, Issue:3

    Topics: Acute-Phase Reaction; Adolescent; Adult; Catheters, Indwelling; Deferoxamine; Female; Heart Failure;

1992