deferoxamine has been researched along with Acute Hepatic Failure in 6 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "N-acetylcysteine plus deferoxamine treatment significantly attenuated hepatic and central nervous system oxidative damage after acute hepatic failure induced by CCl4." | 7.72 | Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. ( Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J, 2004) |
| "N-acetylcysteine plus deferoxamine treatment significantly attenuated hepatic and central nervous system oxidative damage after acute hepatic failure induced by CCl4." | 3.72 | Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats. ( Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J, 2004) |
| "Treatment with deferoxamine was prompt and followed by empiric N-acetylcysteine once liver injury was apparent." | 1.33 | Acute liver failure due to iron overdose in an adult. ( Daram, SR; Hayashi, PH, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, N | 1 |
| Karasawa, T | 1 |
| Kimura, H | 1 |
| Watanabe, S | 1 |
| Komada, T | 1 |
| Kamata, R | 1 |
| Sampilvanjil, A | 1 |
| Ito, J | 1 |
| Nakagawa, K | 1 |
| Kuwata, H | 1 |
| Hara, S | 1 |
| Mizuta, K | 1 |
| Sakuma, Y | 1 |
| Sata, N | 1 |
| Takahashi, M | 1 |
| Arkadopoulos, N | 1 |
| Vlahakos, D | 2 |
| Kostopanagiotou, G | 1 |
| Panagopoulos, D | 2 |
| Karvouni, E | 1 |
| Routsi, C | 2 |
| Kalimeris, K | 1 |
| Andreadou, I | 1 |
| Kouskouni, E | 1 |
| Smyrniotis, V | 2 |
| Kostopanagiotou, GG | 1 |
| Kalimeris, KA | 1 |
| Arkadopoulos, NP | 1 |
| Pafiti, A | 1 |
| Lekka, ME | 1 |
| Nakos, G | 1 |
| Ritter, C | 1 |
| Reinke, A | 1 |
| Andrades, M | 1 |
| Martins, MR | 1 |
| Rocha, J | 1 |
| Menna-Barreto, S | 1 |
| Quevedo, J | 1 |
| Moreira, JC | 1 |
| Dal-Pizzol, F | 1 |
| Daram, SR | 1 |
| Hayashi, PH | 1 |
| Venkat-Raman, N | 1 |
| Venkata-Krishnan, RV | 1 |
| Howarth, ES | 1 |
6 other studies available for deferoxamine and Acute Hepatic Failure
| Article | Year |
|---|---|
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.
Topics: Acetaminophen; alpha-Tocopherol; Animals; Antioxidants; Coenzyme A Ligases; Cyclohexylamines; Cycloo | 2020 |
Iron chelation attenuates intracranial pressure and improves survival in a swine model of acute liver failure.
Topics: Animals; Brain; Central Venous Pressure; Cytokines; Deferoxamine; Disease Models, Animal; Female; In | 2008 |
Desferrioxamine attenuates minor lung injury following surgical acute liver failure.
Topics: Acute Lung Injury; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Catalase; Deferoxami | 2009 |
Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Deferoxamine; Hydrocarbons; Inflammatio | 2004 |
Acute liver failure due to iron overdose in an adult.
Topics: Adolescent; Alanine Transaminase; Deferoxamine; Drug Overdose; Female; Humans; Iron; Iron Chelating | 2005 |
Successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with recurrent perinatal haemochromatosis.
Topics: Acetylcysteine; Adult; Deferoxamine; Diagnosis, Differential; Female; Ferritins; Fetal Diseases; Fre | 2006 |