deferoxamine has been researched along with Achromatopsia in 2 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Achromatopsia: Severely deficient color perception, typically with monochromacy and reduced visual acuity. The atypical form can include normal visual acuity with pseudomonochromacy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of 89 patients receiving nightly subcutaneous deferoxamine for transfusion-dependent thalassemia major or Diamond-Blackfan anemia, 13 presented with visual loss or deafness of acute onset or both." | 3.67 | Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions. ( Buncic, JR; Chew, E; Gallant, T; Harrison, RV; Keenan, N; Logan, W; Mitchell, D; Olivieri, NF; Ricci, G; Skarf, B, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mehta, AM | 1 |
| Engstrom, RE | 1 |
| Kreiger, AE | 1 |
| Olivieri, NF | 1 |
| Buncic, JR | 1 |
| Chew, E | 1 |
| Gallant, T | 1 |
| Harrison, RV | 1 |
| Keenan, N | 1 |
| Logan, W | 1 |
| Mitchell, D | 1 |
| Ricci, G | 1 |
| Skarf, B | 1 |
2 other studies available for deferoxamine and Achromatopsia
| Article | Year |
|---|---|
Deferoxamine-associated retinopathy after subcutaneous injection.
Topics: Aged; Anemia, Refractory; Color Vision Defects; Deferoxamine; Female; Fluorescein Angiography; Fundu | 1994 |
Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions.
Topics: Adolescent; Adult; Age Factors; Anemia, Aplastic; Audiometry; Child; Child, Preschool; Color Vision | 1986 |