deferoxamine has been researched along with 4 Hydroxyphenylpyruvate Dioxygenase Deficiency Disease in 1 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Considering that the mechanisms underlying the neurological dysfunction in hypertyrosinemic patients are poorly known and that high concentrations of tyrosine provoke mitochondrial dysfunction and oxidative stress, in the present study we investigated the in vivo influence of antioxidants (N-acetylcysteine, NAC; and deferoxamine, DFX) administration on the inhibitory effects on parameters of energy metabolism in cerebral cortex, hippocampus and striatum of rats, provoked by chronic administration of L." | 1.46 | Antioxidants reverse the changes in energy metabolism of rat brain after chronic administration of L.-tyrosine. ( Carvalho-Silva, M; De Prá, SD; Ferreira, GC; Gomes, LM; Rebelo, J; Scaini, G; Schuck, PF; Streck, EL; Teixeira, LJ; Teodorak, BP; Zeni, N, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teodorak, BP | 1 |
| Scaini, G | 1 |
| Carvalho-Silva, M | 1 |
| Gomes, LM | 1 |
| Teixeira, LJ | 1 |
| Rebelo, J | 1 |
| De Prá, SD | 1 |
| Zeni, N | 1 |
| Schuck, PF | 1 |
| Ferreira, GC | 1 |
| Streck, EL | 1 |
1 other study available for deferoxamine and 4 Hydroxyphenylpyruvate Dioxygenase Deficiency Disease
| Article | Year |
|---|---|
Antioxidants reverse the changes in energy metabolism of rat brain after chronic administration of L.-tyrosine.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Chemistry; Citrate (si)-Synthase; Citric Acid Cycle; Cr | 2017 |