deferiprone has been researched along with Uremia in 3 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " According to the results of this study, uremia did not increase the toxic effects of L1." | 1.29 | Four-week oral toxicity study of 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in uremic rats. ( Corbella, J; del Castillo, D; Domingo, JL; Gomez, M; Llobet, JM, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gómez, M | 3 |
| Domingo, JL | 3 |
| del Castillo, D | 3 |
| Llobet, JM | 2 |
| Corbella, J | 2 |
| Esparza, JL | 1 |
| Hernández, M | 1 |
3 other studies available for deferiprone and Uremia
| Article | Year |
|---|---|
Comparative aluminium mobilizing actions of several chelators in aluminium-loaded uraemic rats.
Topics: Aluminum; Animals; Chelating Agents; Citrates; Citric Acid; Deferiprone; Deferoxamine; Female; Injec | 1994 |
Four-week oral toxicity study of 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in uremic rats.
Topics: Administration, Oral; Aluminum; Analysis of Variance; Animals; Blood Cells; Blood Chemical Analysis; | 1995 |
Age-Related differences on aluminium mobilization by chelating agents in aluminium-loaded uraemic rats.
Topics: Administration, Oral; Aging; Aluminum; Aluminum Compounds; Animals; Anthelmintics; Chelating Agents; | 2000 |