deferiprone has been researched along with Thrombocytopenia in 5 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Thrombocytopenia: A subnormal level of BLOOD PLATELETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Enrolled patients (9 with β-thalassemia major and 33 with β-thalassemia hemoglobin E), ranging from 3 to 18 years in age, were divided into 3 groups; group 1 ferritin ≥1,000-2,500 ng/ml (n = 10), group 2 ferritin >2,500-4,000 ng/ml (n = 23) and group 3 ferritin >4,000 ng/ml (n = 9)." | 2.80 | Combined chelation therapy with daily oral deferiprone and twice-weekly subcutaneous infusion of desferrioxamine in children with β-thalassemia: 3-year experience. ( Chuansumrit, A; Kadegasem, P; Sasanakul, W; Sirachainan, N; Songdej, D; Sungkarat, W; Wongwerawattanakoon, P, 2015) |
| "Thrombocytopenia is one of the major side effects in young thalassaemics and necessitates frequent close monitoring of blood counts but its resolution after discontinuation and absence of clinical evidence of bleeding does not preclude its use." | 2.71 | Safety of oral iron chelator deferiprone in young thalassaemics. ( Chandra, J; Naithani, R; Sharma, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Songdej, D | 1 |
| Sirachainan, N | 1 |
| Wongwerawattanakoon, P | 1 |
| Sasanakul, W | 1 |
| Kadegasem, P | 1 |
| Sungkarat, W | 1 |
| Chuansumrit, A | 1 |
| Naithani, R | 1 |
| Chandra, J | 1 |
| Sharma, S | 1 |
| Sheikh-Taha, M | 1 |
| Koussa, S | 1 |
| Taher, A | 1 |
| Alter, BP | 1 |
| Hoffbrand, AV | 1 |
| Bartlett, AN | 1 |
| Veys, PA | 1 |
| O'Connor, NT | 1 |
| Kontoghiorghes, GJ | 1 |
2 trials available for deferiprone and Thrombocytopenia
| Article | Year |
|---|---|
Combined chelation therapy with daily oral deferiprone and twice-weekly subcutaneous infusion of desferrioxamine in children with β-thalassemia: 3-year experience.
Topics: Administration, Oral; Adolescent; Alanine Transaminase; beta-Thalassemia; Child; Child, Preschool; C | 2015 |
Safety of oral iron chelator deferiprone in young thalassaemics.
Topics: Blood Cell Count; Child; Child, Preschool; Deferiprone; Female; Follow-Up Studies; Humans; Iron Chel | 2005 |
3 other studies available for deferiprone and Thrombocytopenia
| Article | Year |
|---|---|
Isolated thrombocytopenia associated with hydroxyurea/deferiprone (L1) therapy in a sickle beta thalassemia patient.
Topics: Adult; Antisickling Agents; beta-Thalassemia; Deferiprone; Drug Therapy, Combination; Humans; Hydrox | 2006 |
Agranulocytosis and thrombocytopenia, Blackfan-Diamond anaemia, and oral chelation.
Topics: Administration, Oral; Agranulocytosis; Anemia; Deferiprone; Humans; Iron Chelating Agents; Leukocyte | 1990 |
Agranulocytosis and thrombocytopenia in patient with Blackfan-Diamond anaemia during oral chelator trial.
Topics: Adult; Agranulocytosis; Anemia, Aplastic; Deferiprone; Female; Humans; Iron Chelating Agents; Pyrido | 1989 |