Page last updated: 2024-10-25

deferiprone and Neoplasms

deferiprone has been researched along with Neoplasms in 4 studies

Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Iron mobilization from transferrin is one of the most important screening methods for the selection of chelators intended for clinical use in the treatment of iron overload in thalassemia and other conditions."8.83Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone. Implications in the treatment of thalassemia, anemia of chronic disease, cancer and other conditions. ( Kontoghiorghes, GJ, 2006)
"Iron mobilization from transferrin is one of the most important screening methods for the selection of chelators intended for clinical use in the treatment of iron overload in thalassemia and other conditions."4.83Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone. Implications in the treatment of thalassemia, anemia of chronic disease, cancer and other conditions. ( Kontoghiorghes, GJ, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Wu, Q1
Young, B1
Wang, Y1
Davidoff, AM1
Rankovic, Z1
Yang, J1
Khodaverdian, V1
Tapadar, S1
MacDonald, IA1
Xu, Y1
Ho, PY1
Bridges, A1
Rajpurohit, P1
Sanghani, BA1
Fan, Y1
Thangaraju, M1
Hathaway, NA1
Oyelere, AK1
Bedford, MR1
Ford, SJ1
Horniblow, RD1
Iqbal, TH1
Tselepis, C1
Kontoghiorghes, GJ1

Reviews

3 reviews available for deferiprone and Neoplasms

ArticleYear
Recent Advances with KDM4 Inhibitors and Potential Applications.
    Journal of medicinal chemistry, 2022, 07-28, Volume: 65, Issue:14

    Topics: Enzyme Inhibitors; Histone Demethylases; Humans; Jumonji Domain-Containing Histone Demethylases; Neo

2022
Iron chelation in the treatment of cancer: a new role for deferasirox?
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:9

    Topics: Animals; Antineoplastic Agents; Benzoates; Deferasirox; Deferiprone; Deferoxamine; Humans; Iron Chel

2013
Iron mobilization from transferrin and non-transferrin-bound-iron by deferiprone. Implications in the treatment of thalassemia, anemia of chronic disease, cancer and other conditions.
    Hemoglobin, 2006, Volume: 30, Issue:2

    Topics: Anemia; Chelation Therapy; Chronic Disease; Combined Modality Therapy; Deferiprone; Humans; Iron; Ir

2006

Other Studies

1 other study available for deferiprone and Neoplasms

ArticleYear
Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study.
    Scientific reports, 2019, 03-18, Volume: 9, Issue:1

    Topics: Animals; Catalytic Domain; Cell Line, Tumor; Deferiprone; DNA Methylation; Enzyme Assays; Enzyme Inh

2019