deferiprone has been researched along with Metabolic Diseases in 1 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
Excerpt | Relevance | Reference |
---|---|---|
"Deferiprone (L1) has been shown to be effective and safe in the reversal of accelerating oxidative stress related tissue damage in iron loading and non iron loading conditions such as cardiomyopathy in thalassaemia, acute kidney disease and Friedreich ataxia." | 2.45 | Prospects for introducing deferiprone as potent pharmaceutical antioxidant. ( Kontoghiorghes, GJ, 2009) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kontoghiorghes, GJ | 1 |
1 review available for deferiprone and Metabolic Diseases
Article | Year |
---|---|
Prospects for introducing deferiprone as potent pharmaceutical antioxidant.
Topics: Antioxidants; Chelation Therapy; Copper; Deferiprone; Drug Discovery; Free Radicals; Humans; Iron; I | 2009 |