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deferiprone and Metabolic Diseases

deferiprone has been researched along with Metabolic Diseases in 1 studies

Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.

Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)

Research Excerpts

ExcerptRelevanceReference
"Deferiprone (L1) has been shown to be effective and safe in the reversal of accelerating oxidative stress related tissue damage in iron loading and non iron loading conditions such as cardiomyopathy in thalassaemia, acute kidney disease and Friedreich ataxia."2.45Prospects for introducing deferiprone as potent pharmaceutical antioxidant. ( Kontoghiorghes, GJ, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kontoghiorghes, GJ1

Reviews

1 review available for deferiprone and Metabolic Diseases

ArticleYear
Prospects for introducing deferiprone as potent pharmaceutical antioxidant.
    Frontiers in bioscience (Elite edition), 2009, 06-01, Volume: 1, Issue:1

    Topics: Antioxidants; Chelation Therapy; Copper; Deferiprone; Drug Discovery; Free Radicals; Humans; Iron; I

2009