deferiprone has been researched along with Malaria, Falciparum in 5 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conducted a prospective, double-blind, placebo-controlled, cross-over trial of deferiprone (L1; CP20; 1,2-dimethyl-3-hydroxypyridin-4-one) in 25 adult Zambians with asymptomatic Plasmodium falciparum parasitemia." | 9.08 | Assessment of the effect of the oral iron chelator deferiprone on asymptomatic Plasmodium falciparum parasitemia in humans. ( Biemba, G; Brittenham, GM; Fassos, FF; Gordeuk, VR; Koren, G; Mabeza, GF; McClelland, RA; Olivieri, NF; Parry, D; Thuma, PE; Zulu, S, 1998) |
| "Deferiprone (L1) seems to be a promising agent as an adjuvant in the treatment for severe P." | 6.70 | Deferiprone (L1) as an adjuvant therapy for Plasmodium falciparum malaria. ( Ghosh, K; Karnad, D; Mohanty, D; Pathare, AV, 2002) |
| " We conducted a prospective, double-blind, placebo-controlled, cross-over trial of deferiprone (L1; CP20; 1,2-dimethyl-3-hydroxypyridin-4-one) in 25 adult Zambians with asymptomatic Plasmodium falciparum parasitemia." | 5.08 | Assessment of the effect of the oral iron chelator deferiprone on asymptomatic Plasmodium falciparum parasitemia in humans. ( Biemba, G; Brittenham, GM; Fassos, FF; Gordeuk, VR; Koren, G; Mabeza, GF; McClelland, RA; Olivieri, NF; Parry, D; Thuma, PE; Zulu, S, 1998) |
| "Deferiprone (L1) seems to be a promising agent as an adjuvant in the treatment for severe P." | 2.70 | Deferiprone (L1) as an adjuvant therapy for Plasmodium falciparum malaria. ( Ghosh, K; Karnad, D; Mohanty, D; Pathare, AV, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maneekesorn, S | 1 |
| Chuljerm, H | 1 |
| Koonyosying, P | 1 |
| Uthaipibull, C | 1 |
| Ma, Y | 1 |
| Srichairatanakool, S | 1 |
| Mohanty, D | 2 |
| Ghosh, K | 1 |
| Pathare, AV | 1 |
| Karnad, D | 1 |
| Gordeuk, VR | 2 |
| Loyevsky, M | 1 |
| Thuma, PE | 1 |
| Olivieri, NF | 1 |
| Mabeza, GF | 1 |
| Biemba, G | 1 |
| Parry, D | 1 |
| Zulu, S | 1 |
| Fassos, FF | 1 |
| McClelland, RA | 1 |
| Koren, G | 1 |
| Brittenham, GM | 1 |
1 review available for deferiprone and Malaria, Falciparum
| Article | Year |
|---|---|
Antimalarial effect of iron chelators.
Topics: Animals; Antimalarials; Child; Deferiprone; Deferoxamine; Drug Therapy, Combination; Humans; In Vitr | 2002 |
2 trials available for deferiprone and Malaria, Falciparum
| Article | Year |
|---|---|
Deferiprone (L1) as an adjuvant therapy for Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Coma; Deferiprone; Double-Blind | 2002 |
Assessment of the effect of the oral iron chelator deferiprone on asymptomatic Plasmodium falciparum parasitemia in humans.
Topics: Administration, Oral; Adult; Area Under Curve; Cross-Over Studies; Deferiprone; Dose-Response Relati | 1998 |
2 other studies available for deferiprone and Malaria, Falciparum
| Article | Year |
|---|---|
Identifying a Deferiprone-Resveratrol Hybrid as an Effective Lipophilic Anti-Plasmodial Agent.
Topics: Antimalarials; Antioxidants; Deferiprone; Erythrocytes; Humans; Iron Chelating Agents; Malaria, Falc | 2021 |
Red cell adhesion in cerebral malaria.
Topics: Animals; Cell Adhesion; Deferiprone; Erythrocytes; Humans; Malaria, Cerebral; Malaria, Falciparum; P | 2007 |