deferiprone has been researched along with Lupus Erythematosus, Systemic in 4 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment of NZB/W mice with the iron chelator deferiprone significantly delayed the onset of albuminuria and reduced blood urea nitrogen concentrations." | 3.85 | Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria. ( Boesen, EI; Bonnemaison, ML; Brusnahan, SK; Fan, W; Garrison, JC; Marks, ES; Zhang, W, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marks, ES | 1 |
| Bonnemaison, ML | 1 |
| Brusnahan, SK | 1 |
| Zhang, W | 1 |
| Fan, W | 1 |
| Garrison, JC | 1 |
| Boesen, EI | 1 |
| Fritzler, MJ | 1 |
| Mehta, J | 1 |
| Singhal, S | 1 |
| Revankar, R | 1 |
| Walvalkar, A | 1 |
| Chablani, A | 1 |
| Mehta, BC | 1 |
| Olivieri, NF | 1 |
| Koren, G | 1 |
| Freedman, MH | 1 |
| Roifman, C | 1 |
1 review available for deferiprone and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Drugs recently associated with lupus syndromes.
Topics: Deferiprone; Humans; Interferon-alpha; Interleukin-2; Leuprolide; Lupus Erythematosus, Systemic; Pen | 1994 |
3 other studies available for deferiprone and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Renal iron accumulation occurs in lupus nephritis and iron chelation delays the onset of albuminuria.
Topics: Albuminuria; Animals; Deferiprone; Disease Models, Animal; Iron; Iron Chelating Agents; Iron-Binding | 2017 |
Fatal systemic lupus erythematosus in patient taking oral iron chelator L1.
Topics: Adolescent; Antibodies, Antinuclear; Child; Deferiprone; Female; Humans; Lupus Erythematosus, System | 1991 |
Rarity of systemic lupus erythematosus after oral iron chelator L1.
Topics: Deferiprone; Humans; Iron Chelating Agents; Lupus Erythematosus, Systemic; Pyridones | 1991 |