deferiprone has been researched along with Fanconi Anemia in 2 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A FA patient started to receive deferiprone (L1) therapy due to iron overload." | 7.75 | Treatment with deferiprone for iron overload alleviates bone marrow failure in a Fanconi anemia patient. ( Chang, YH; Hsieh, KH; Lu, PJ; Shaw, CF; Su, YN; Wu, KH, 2009) |
| " A FA patient started to receive deferiprone (L1) therapy due to iron overload." | 3.75 | Treatment with deferiprone for iron overload alleviates bone marrow failure in a Fanconi anemia patient. ( Chang, YH; Hsieh, KH; Lu, PJ; Shaw, CF; Su, YN; Wu, KH, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Voter, AF | 1 |
| Manthei, KA | 1 |
| Keck, JL | 1 |
| Chang, YH | 1 |
| Shaw, CF | 1 |
| Wu, KH | 1 |
| Hsieh, KH | 1 |
| Su, YN | 1 |
| Lu, PJ | 1 |
2 other studies available for deferiprone and Fanconi Anemia
| Article | Year |
|---|---|
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
Topics: Antineoplastic Agents; DNA Damage; DNA Helicases; DNA Repair; Drug Screening Assays, Antitumor; Fanc | 2016 |
Treatment with deferiprone for iron overload alleviates bone marrow failure in a Fanconi anemia patient.
Topics: Bone Marrow; Child; Deferiprone; Fanconi Anemia; Ferritins; Hematopoietic Stem Cell Transplantation; | 2009 |