Page last updated: 2024-10-25

deferiprone and Diabetic Glomerulosclerosis

deferiprone has been researched along with Diabetic Glomerulosclerosis in 4 studies

Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.

Research Excerpts

ExcerptRelevanceReference
"Diabetic nephropathy was induced in rats by feeding on high-carbohydrate-fat food and injecting streptozotocin."1.39Iron chelator alleviates tubulointerstitial fibrosis in diabetic nephropathy rats by inhibiting the expression of tenascinC and other correlation factors. ( Bao, Y; Li, S; Liu, X; M, S; Sui, M; Xie, R; Yin, H; Zou, C, 2013)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaudhary, K1
Chilakala, A1
Ananth, S1
Mandala, A1
Veeranan-Karmegam, R1
Powell, FL1
Ganapathy, V1
Gnana-Prakasam, JP1
Zou, C2
Xie, R2
Bao, Y1
Liu, X2
Sui, M2
M, S1
Li, S1
Yin, H1
Liu, R1
Wang, M1
Mu, S1
Li, L1
Ji, L1
Rajapurkar, MM1
Hegde, U1
Bhattacharya, A1
Alam, MG1
Shah, SV1

Trials

1 trial available for deferiprone and Diabetic Glomerulosclerosis

ArticleYear
Effect of deferiprone, an oral iron chelator, in diabetic and non-diabetic glomerular disease.
    Toxicology mechanisms and methods, 2013, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Deferiprone; Diabetic Nephropathies; Drug Therapy, Combi

2013

Other Studies

3 other studies available for deferiprone and Diabetic Glomerulosclerosis

ArticleYear
Renal iron accelerates the progression of diabetic nephropathy in the HFE gene knockout mouse model of iron overload.
    American journal of physiology. Renal physiology, 2019, 08-01, Volume: 317, Issue:2

    Topics: Animals; Deferiprone; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression;

2019
Iron chelator alleviates tubulointerstitial fibrosis in diabetic nephropathy rats by inhibiting the expression of tenascinC and other correlation factors.
    Endocrine, 2013, Volume: 44, Issue:3

    Topics: Animals; Deferiprone; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Iron Chelating Agents

2013
Effect of the oral iron chelator deferiprone in diabetic nephropathy rats.
    Journal of diabetes, 2017, Volume: 9, Issue:4

    Topics: Administration, Oral; Animals; Blotting, Western; Chemokine CCL2; Cyclooxygenase 2; Deferiprone; Dia

2017