Page last updated: 2024-10-25

deferiprone and Arthritis, Rheumatoid

deferiprone has been researched along with Arthritis, Rheumatoid in 4 studies

Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.

Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berkovitch, M1
Laxer, RM1
Inman, R1
Koren, G1
Pritzker, KP1
Fritzler, MJ1
Olivieri, NF1
Norga, K1
Grillet, B1
Masure, S1
Paemen, L1
Opdenakker, G1
Vreugdenhil, G2
Swaak, AJ2
de Jeu-Jaspers, C1
van Eijk, HG2
Kontoghiorghes, GJ1

Trials

1 trial available for deferiprone and Arthritis, Rheumatoid

ArticleYear
Efficacy and safety of oral iron chelator L1 in anaemic rheumatoid arthritis patients.
    Lancet (London, England), 1989, Dec-09, Volume: 2, Issue:8676

    Topics: Administration, Oral; Anemia; Arthritis, Rheumatoid; Deferiprone; Humans; Iron Chelating Agents; Pyr

1989

Other Studies

3 other studies available for deferiprone and Arthritis, Rheumatoid

ArticleYear
Arthropathy in thalassaemia patients receiving deferiprone.
    Lancet (London, England), 1994, Jun-11, Volume: 343, Issue:8911

    Topics: Adolescent; Adult; Arthritis, Rheumatoid; beta-Thalassemia; Deferiprone; Humans; Iron Chelating Agen

1994
Human gelatinase B, a marker enzyme in rheumatoid arthritis, is inhibited by D-penicillamine: anti-rheumatic activity by protease inhibition.
    Clinical rheumatology, 1996, Volume: 15, Issue:1

    Topics: Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Collagenases; Deferi

1996
Correlation of iron exchange between the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one(L1) and transferrin and possible antianaemic effects of L1 in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1990, Volume: 49, Issue:11

    Topics: Anemia; Arthritis, Rheumatoid; Deferiprone; Humans; Iron Chelating Agents; Pyridones

1990