deferiprone has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Devos, D | 2 |
| Cabantchik, ZI | 2 |
| Moreau, C | 2 |
| Danel, V | 2 |
| Mahoney-Sanchez, L | 1 |
| Bouchaoui, H | 1 |
| Gouel, F | 2 |
| Rolland, AS | 1 |
| Duce, JA | 1 |
| Devedjian, JC | 2 |
| Grolez, G | 1 |
| Timmerman, K | 1 |
| Laloux, C | 1 |
| Petrault, M | 1 |
| Jonneaux, A | 1 |
| Dutheil, M | 1 |
| Lachaud, C | 1 |
| Lopes, R | 1 |
| Kuchcinski, G | 1 |
| Auger, F | 1 |
| Kyheng, M | 1 |
| Duhamel, A | 1 |
| Pérez, T | 1 |
| Pradat, PF | 1 |
| Blasco, H | 1 |
| Veyrat-Durebex, C | 1 |
| Corcia, P | 1 |
| Oeckl, P | 1 |
| Otto, M | 1 |
| Dupuis, L | 1 |
| Garçon, G | 1 |
| Defebvre, L | 1 |
| Duce, J | 1 |
| Bordet, R | 1 |
1 review available for deferiprone and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Conservative iron chelation for neurodegenerative diseases such as Parkinson's disease and amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Chelation Therapy; Deferiprone; Humans; Iron; Iron Chelating | 2020 |
1 trial available for deferiprone and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?
Topics: Adult; Amyotrophic Lateral Sclerosis; Animals; Deferiprone; Disease Models, Animal; Dose-Response Re | 2018 |