Page last updated: 2024-10-25

deferiprone and Aging

deferiprone has been researched along with Aging in 4 studies

Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Deferiprone (DFP) is a clinically available iron chelator, which has demonstrated potential therapeutic advantages of chelating iron in neurodegenerative disorders, and is currently in clinical trials for AD."1.62Deferiprone Treatment in Aged Transgenic Tau Mice Improves Y-Maze Performance and Alters Tau Pathology. ( Adlard, PA; Finkelstein, DI; Lago, L; McColl, G; Rao, SS; Shukla, JJ; Volitakis, I, 2021)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Rao, SS1
Lago, L1
Volitakis, I1
Shukla, JJ1
McColl, G1
Finkelstein, DI1
Adlard, PA1
Crowe, A1
Morgan, EH1
Gómez, M2
Esparza, JL2
Domingo, JL2
Singh, PK1
Jones, MM1
del Castillo, D1
Hernández, M1

Other Studies

4 other studies available for deferiprone and Aging

ArticleYear
Deferiprone Treatment in Aged Transgenic Tau Mice Improves Y-Maze Performance and Alters Tau Pathology.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:2

    Topics: Aging; Animals; Deferiprone; Female; Humans; Iron Chelating Agents; Male; Maze Learning; Mice; Mice,

2021
Effects of chelators on iron uptake and release by the brain in the rat.
    Neurochemical research, 1994, Volume: 19, Issue:1

    Topics: 2,2'-Dipyridyl; Aging; Animals; Biological Transport; Bone and Bones; Brain; Deferiprone; Deferoxami

1994
Chelation therapy in aluminum-loaded rats: influence of age.
    Toxicology, 1999, Oct-01, Volume: 137, Issue:3

    Topics: Aging; Aluminum; Animals; Antidotes; Chelating Agents; Chelation Therapy; Deferiprone; Deferoxamine;

1999
Age-Related differences on aluminium mobilization by chelating agents in aluminium-loaded uraemic rats.
    Pharmacology & toxicology, 2000, Volume: 87, Issue:1

    Topics: Administration, Oral; Aging; Aluminum; Aluminum Compounds; Animals; Anthelmintics; Chelating Agents;

2000