deferiprone has been researched along with Acute Liver Injury, Drug-Induced in 5 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 20-year-old male affected by transfusion-dependent β-thalassemia (β-thal), was prescribed intensive chelation therapy with deferoxamine (DFO) and deferiprone (DFP) because of severe hepatic and cardiac iron overload and β-blocker and warfarin to manage a previous event of atrial fibrillation (AFib) and heart failure." | 3.88 | Life-Threatening Drug-Induced Liver Injury in a Patient with β-Thalassemia Major and Severe Iron Overload on Polypharmacy. ( Casale, M; Cerasari, G; Corvino, F; Perrotta, S; Persico, M; Picariello, S; Rossi, F; Scianguetta, S, 2018) |
| "Tamoxifen (TAM) is a non-steroidal antiestrogen used in the treatment and prevention of hormone-dependent breast cancer." | 1.37 | The effect of the oral iron chelator deferiprone on the liver damage induced by tamoxifen in female rats. ( Cerná, P; Eybl, V; Kotyzová, D, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Casale, M | 1 |
| Picariello, S | 1 |
| Corvino, F | 1 |
| Cerasari, G | 1 |
| Scianguetta, S | 1 |
| Rossi, F | 1 |
| Persico, M | 1 |
| Perrotta, S | 1 |
| Totadri, S | 1 |
| Bansal, D | 1 |
| Bhatia, P | 1 |
| Attri, SV | 1 |
| Trehan, A | 1 |
| Marwaha, RK | 1 |
| Cerná, P | 1 |
| Kotyzová, D | 1 |
| Eybl, V | 1 |
| Hershko, CM | 1 |
| Link, GM | 1 |
| Konijn, AM | 1 |
| Cabantchik, ZI | 1 |
| al-Refaie, FN | 1 |
| Hershko, C | 1 |
| Hoffbrand, AV | 1 |
| Kosaryan, M | 1 |
| Olivieri, NF | 1 |
| Tondury, P | 1 |
| Wonke, B | 1 |
5 other studies available for deferiprone and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Life-Threatening Drug-Induced Liver Injury in a Patient with β-Thalassemia Major and Severe Iron Overload on Polypharmacy.
Topics: Adrenergic beta-Antagonists; beta-Thalassemia; Chelation Therapy; Chemical and Drug Induced Liver In | 2018 |
The deferiprone and deferasirox combination is efficacious in iron overloaded patients with β-thalassemia major: A prospective, single center, open-label study.
Topics: Adolescent; Adult; Benzoates; beta-Thalassemia; Chelation Therapy; Chemical and Drug Induced Liver I | 2015 |
The effect of the oral iron chelator deferiprone on the liver damage induced by tamoxifen in female rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Deferiprone; Enzyme Assays; Female; Iron; Iron Chel | 2011 |
Iron chelation therapy.
Topics: Administration, Oral; Benzoates; beta-Thalassemia; Chelation Therapy; Chemical and Drug Induced Live | 2005 |
Results of long-term deferiprone (L1) therapy: a report by the International Study Group on Oral Iron Chelators.
Topics: Adult; Agranulocytosis; Arthritis; beta-Thalassemia; Chemical and Drug Induced Liver Injury; Deferip | 1995 |