deferiprone has been researched along with Ache in 5 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In previous trials, the orally active iron chelator deferiprone (L1) has been associated with sporadic agranulocytosis, milder forms of neutropenia and other side-effects." | 3.70 | Safety profile of the oral iron chelator deferiprone: a multicentre study. ( Cohen, AR; Dipalma, A; Galanello, R; Piga, A; Tricta, F; Vullo, C, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inati, A | 2 |
| Khoriaty, E | 1 |
| Musallam, KM | 1 |
| Taher, AT | 1 |
| Adhikari, D | 1 |
| Cohen, AR | 1 |
| Galanello, R | 1 |
| Piga, A | 1 |
| Dipalma, A | 1 |
| Vullo, C | 1 |
| Tricta, F | 1 |
| Taher, A | 1 |
| Sheikh-Taha, M | 1 |
| Koussa, S | 1 |
| Neeman, R | 1 |
| Mourad, F | 1 |
| Agarwal, MB | 1 |
| Gupte, SS | 1 |
| Viswanathan, C | 1 |
| Vasandani, D | 1 |
| Ramanathan, J | 1 |
| Desai, N | 1 |
| Puniyani, RR | 1 |
| Chhablani, AT | 1 |
2 trials available for deferiprone and Ache
| Article | Year |
|---|---|
Comparison between deferoxamine and deferiprone (L1) in iron-loaded thalassemia patients.
Topics: Administration, Oral; Adolescent; Adult; beta-Thalassemia; Chelation Therapy; Child; Deferiprone; De | 2001 |
Long-term assessment of efficacy and safety of L1, an oral iron chelator, in transfusion dependent thalassaemia: Indian trial.
Topics: Adolescent; Adult; beta-Thalassemia; Child; Deferiprone; Deferoxamine; Humans; Iron; Iron Chelating | 1992 |
3 other studies available for deferiprone and Ache
| Article | Year |
|---|---|
Iron chelation therapy for patients with sickle cell disease and iron overload.
Topics: Administration, Oral; Anemia, Sickle Cell; Benzoates; Chelation Therapy; Child; Deferasirox; Deferip | 2010 |
Deferiprone in iron overload.
Topics: Deferiprone; Gastrointestinal Diseases; Humans; Iron Chelating Agents; Joint Diseases; Neutropenia; | 1995 |
Safety profile of the oral iron chelator deferiprone: a multicentre study.
Topics: Agranulocytosis; Alanine Transaminase; beta-Thalassemia; Deferiprone; Gastrointestinal Diseases; Hum | 2000 |