deferiprone has been researched along with Abnormalities, Autosome in 1 studies
Deferiprone: A pyridone derivative and iron chelator that is used in the treatment of IRON OVERLOAD in patients with THALASSEMIA.
deferiprone : A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Measurements of chromosomal aberrations were made in 10 thalassaemia major patients treated long-term with deferiprone (at least 5 years) and compared with an equal number of patients matched for age, sex and iron overload, treated long-term with deferoxamine." | 2.71 | Chromosomal aberration frequencies in patients with thalassaemia major undergoing therapy with deferiprone and deferoxamine in a comparative crossover study. ( Galanello, R; Kirkland, D; Leoni, G; Marshall, R; Minto, S; Spino, M; Tricta, F, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marshall, R | 1 |
| Tricta, F | 1 |
| Galanello, R | 1 |
| Leoni, G | 1 |
| Kirkland, D | 1 |
| Minto, S | 1 |
| Spino, M | 1 |
1 trial available for deferiprone and Abnormalities, Autosome
| Article | Year |
|---|---|
Chromosomal aberration frequencies in patients with thalassaemia major undergoing therapy with deferiprone and deferoxamine in a comparative crossover study.
Topics: Adolescent; Adult; beta-Thalassemia; Cell Cycle; Chelation Therapy; Chromosome Aberrations; Cross-Ov | 2003 |