Page last updated: 2024-09-05

deferasirox and Carcinoma, Hepatocellular

deferasirox has been researched along with Carcinoma, Hepatocellular in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Akita, T; Jomen, W; Kohgo, Y; Ohtake, T; Osawa, Y; Suto, D; Yagi, H1
Fujisawa, K; Hidaka, I; Ishikawa, T; Iwamoto, T; Maeda, M; Matsumoto, T; Saeki, I; Sakaida, I; Takami, T; Tani, K; Uchida, K; Yamamoto, N; Yamasaki, T1
Brissot, P; Cannie, I; Gaboriau, F; Gouffier, L; Leray, AM; Lescoat, G; Loréal, O; Ropert, M; Troadec, MB1
Aihara, Y; Fukui, H; Ikenaka, Y; Kaji, K; Kawaratani, H; Kitade, M; Namisaki, T; Noguchi, R; Shirai, Y; Tsujimoto, T; Yanase, K; Yoshii, J; Yoshiji, H1
Brissot, P; Chantrel-Groussard, K; Gaboriau, F; Havouis, R; Lescoat, G; Nick, H; Pasdeloup, N; Pierre, JL1
Dassonville, A; Desplat, V; Gaboriau, F; Guillon, J; Jarry, C; Lescoat, G; Nascimento, S; Pires, VS; Rochette, J; Sonnet, P1
Brissot, P; Chantrel-Groussard, K; Gaboriau, F; Lescoat, G; Nick, H; Pasdeloup, N1

Trials

1 trial(s) available for deferasirox and Carcinoma, Hepatocellular

ArticleYear
Effects of an oral iron chelator, deferasirox, on advanced hepatocellular carcinoma.
    World journal of gastroenterology, 2016, Oct-28, Volume: 22, Issue:40

    Topics: Aged; Aged, 80 and over; Animals; Benzoates; Carcinoma, Hepatocellular; Deferasirox; Drug Screening Assays, Antitumor; Female; Hep G2 Cells; Humans; Iron Chelating Agents; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Middle Aged; Triazoles

2016

Other Studies

6 other study(ies) available for deferasirox and Carcinoma, Hepatocellular

ArticleYear
Iron chelator deferasirox inhibits NF-κB activity in hepatoma cells and changes sorafenib-induced programmed cell deaths.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line; Cell Line, Tumor; Deferasirox; Humans; Iron Chelating Agents; Liver Neoplasms; NF-kappa B; Sorafenib

2022
Effects of deferasirox and deferiprone on cellular iron load in the human hepatoma cell line HepaRG.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2010, Volume: 23, Issue:2

    Topics: Benzoates; Carcinoma, Hepatocellular; Cell Line, Tumor; Deferasirox; Deferiprone; Dose-Response Relationship, Drug; Female; Ferritins; Hepatocytes; Humans; Iron; Iron Chelating Agents; Liver Neoplasms; Molecular Structure; Pyridones; Receptors, Transferrin; Triazoles

2010
Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 300, Issue:6

    Topics: Administration, Oral; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzoates; Carcinoma, Hepatocellular; Cell Proliferation; Cells, Cultured; Choline Deficiency; Deferasirox; Disease Progression; Drug Therapy, Combination; Fatty Liver; Hepatic Stellate Cells; Iron Chelating Agents; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Losartan; Male; Neovascularization, Pathologic; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats; Rats, Inbred F344; Time Factors; Transforming Growth Factor beta1; Triazoles

2011
The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox.
    European journal of pharmacology, 2006, Jul-17, Volume: 541, Issue:3

    Topics: Acetyltransferases; Apoptosis; Benzoates; Biogenic Polyamines; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Deferasirox; DNA Replication; Ethylamines; Hepatocytes; Humans; Hydroxyquinolines; Iron Chelating Agents; Ornithine Decarboxylase; RNA, Messenger; Triazoles

2006
Modulation of cell proliferation in rat liver cell cultures by new calix[4]arenes.
    Journal of enzyme inhibition and medicinal chemistry, 2006, Volume: 21, Issue:3

    Topics: Animals; Benzoates; Calixarenes; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Deferasirox; Drug Screening Assays, Antitumor; Hydroxyl Radical; Iron Chelating Agents; Molecular Structure; Phenols; Rats; Solubility; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2006
Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism.
    Cell proliferation, 2007, Volume: 40, Issue:5

    Topics: Animals; Apoptosis; Base Sequence; Benzoates; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemotherapy, Adjuvant; Deferasirox; Deferiprone; DNA Primers; DNA Replication; Humans; Iron Chelating Agents; Liver Neoplasms; Liver Neoplasms, Experimental; Polyamines; Pyridones; Rats; Triazoles

2007