Page last updated: 2024-09-05

deferasirox and Adverse Drug Event

deferasirox has been researched along with Adverse Drug Event in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
El Rassi, F; Saliba, AN; Taher, AT1
Brewer, C; Gonzalez, I; Nick, H; Otto-Duessel, M; Wood, JC1
Cappellini, MD; Porter, JB; Taher, AT; Vichinsky, EP1
Al Jefri, A; Al Zir, K; Daar, S; El-Beshlawy, A; Elalfy, MS; Habr, D; Hmissi, A; Kriemler-Krahn, U; Taher, A1
Kontoghiorghes, GJ1
Berard, F; Martin, O; Nicolas, JF; Rozieres, A; Said, BB1
Hussar, DA1
Goldberg, SL1

Reviews

2 review(s) available for deferasirox and Adverse Drug Event

ArticleYear
Clinical monitoring and management of complications related to chelation therapy in patients with β-thalassemia.
    Expert review of hematology, 2016, Volume: 9, Issue:2

    Topics: Benzoates; beta-Thalassemia; Chelation Therapy; Deferasirox; Deferiprone; Deferoxamine; Disease Management; Drug-Related Side Effects and Adverse Reactions; Female; Ferritins; Humans; Iron; Iron Chelating Agents; Iron Overload; Liver; Magnetic Resonance Imaging; Male; Myocardium; Pregnancy; Pyridones; Triazoles

2016
Novel treatment options for transfusional iron overload in patients with myelodysplastic syndromes.
    Leukemia research, 2007, Volume: 31 Suppl 3

    Topics: Benzoates; Deferasirox; Deferiprone; Drug-Related Side Effects and Adverse Reactions; Humans; Iron Chelating Agents; Iron Overload; Myelodysplastic Syndromes; Pyridones; Survival Rate; Transfusion Reaction; Treatment Outcome; Triazoles

2007

Trials

1 trial(s) available for deferasirox and Adverse Drug Event

ArticleYear
Efficacy and safety of deferasirox, an oral iron chelator, in heavily iron-overloaded patients with beta-thalassaemia: the ESCALATOR study.
    European journal of haematology, 2009, Volume: 82, Issue:6

    Topics: Adolescent; Adult; Benzoates; beta-Thalassemia; Child, Preschool; Deferasirox; Deferiprone; Deferoxamine; Drug-Related Side Effects and Adverse Reactions; Female; Ferritins; Humans; Iron; Iron Chelating Agents; Iron Overload; Liver; Male; Pyridones; Treatment Outcome; Triazoles; Young Adult

2009

Other Studies

8 other study(ies) available for deferasirox and Adverse Drug Event

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Safety and efficacy of combined chelation therapy with deferasirox and deferoxamine in a gerbil model of iron overload.
    Acta haematologica, 2008, Volume: 120, Issue:2

    Topics: Animals; Benzoates; Deferasirox; Deferoxamine; Disease Models, Animal; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Gerbillinae; Heart; Iron Overload; Liver; Organ Size; Treatment Outcome; Triazoles

2008
Ethical issues and risk/benefit assessment of iron chelation therapy: advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox [Kontoghiorghes GJ, Hemoglobin 2008; 32(1-2):1-15.].
    Hemoglobin, 2008, Volume: 32, Issue:6

    Topics: Benzoates; Chelation Therapy; Deferasirox; Deferiprone; Deferoxamine; Drug Costs; Drug-Related Side Effects and Adverse Reactions; Hematologic Diseases; Humans; Iron Chelating Agents; Pyridones; Risk Assessment; Siderophores; Triazoles

2008
A record of 1320 suspect, deferasirox-related, patient deaths reported in 2009: insufficient toxicity testing, low efficacy and lack of transparency may endanger the lives of iron loaded patients.
    Hemoglobin, 2011, Volume: 35, Issue:3

    Topics: Benzoates; Deferasirox; Drug-Related Side Effects and Adverse Reactions; Ethics, Medical; Ethics, Research; Humans; Iron Overload; Triazoles

2011
Severe hypocalcemia and drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome under deferasirox therapy for myelodysplasic syndrome.
    American journal of hematology, 2012, Volume: 87, Issue:2

    Topics: Aged; Benzoates; Deferasirox; Drug-Related Side Effects and Adverse Reactions; Eosinophilia; Female; Humans; Hypocalcemia; Iron Chelating Agents; Myelodysplastic Syndromes; Syndrome; Triazoles

2012
New drugs 06, part II.
    Nursing, 2006, Volume: 36, Issue:8

    Topics: Analgesics; Benzeneacetamides; Benzoates; Bone Density Conservation Agents; Deferasirox; Diphosphonates; Docosahexaenoic Acids; Drug Approval; Drug Combinations; Drug Interactions; Drug Monitoring; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Eicosapentaenoic Acid; gamma-Aminobutyric Acid; Humans; Ibandronic Acid; Iloprost; Indenes; Minocycline; Patient Education as Topic; Phenylacetates; Pregabalin; Tigecycline; Triazoles; Vasodilator Agents

2006