Page last updated: 2024-10-31

deet and Pregnancy

deet has been researched along with Pregnancy in 21 studies

N,N-diethyl-m-toluamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" No adverse neurologic, gastrointestinal, or dermatologic effects were observed for women who applied a median total dose of 214."6.70Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy. ( Cho, T; Edwards, R; Hamilton, KA; Lindsay, SW; Looareesuwan, S; Luxemburger, C; McGready, R; Nosten, F; Simpson, JA; White, NJ, 2001)
" No adverse neurologic, gastrointestinal, or dermatologic effects were observed for women who applied a median total dose of 214."2.70Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy. ( Cho, T; Edwards, R; Hamilton, KA; Lindsay, SW; Looareesuwan, S; Luxemburger, C; McGready, R; Nosten, F; Simpson, JA; White, NJ, 2001)
" This article describes those changes, and summarizes more recent data relating to the pharmacokinetics, toxicology, and epidemiology of adverse effects associated with DEET in humans."2.42DEET: a review and update of safety and risk in the general population. ( Sudakin, DL; Trevathan, WR, 2003)
" However, concerns have been raised over the risk of adverse toxic effects, especially in young children and pregnant and lactating women."1.32DEET-based insect repellents: safety implications for children and pregnant and lactating women. ( Bailey, B; Koren, G; Matsui, D, 2003)
" Rats were administered undiluted DEET by gavage on Gestational Days (gd) 6-15 at dosage levels of 0, 125, 250, and 750 mg/kg/day."1.29Teratologic evaluations of N,N-diethyl-m-toluamide (DEET) in rats and rabbits. ( Fisher, LC; Hartnagel, RE; Neeper-Bradley, TL; Schoenig, GP, 1994)
" No females survived 10 days of mDET dosing with 1."1.28Reproductive and developmental toxicity of N,N-diethyl-m-toluamide in rats. ( Chrislip, DW; Goad, PW; Hardin, BD; Wright, DM, 1992)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's4 (19.05)18.2507
2000's7 (33.33)29.6817
2010's4 (19.05)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Portilla Pulido, JS3
Urbina Duitama, DL3
Velasquez-Martinez, MC3
Mendez-Sanchez, SC3
Duque, JE3
Almeida, AR1
Oliveira, ND1
Pinheiro, FASD1
Morais, WA1
Ferreira, LS1
Thorson, JLM1
Beck, D1
Ben Maamar, M1
Nilsson, EE1
Skinner, MK1
Leuckx, S1
Lewis, RC1
Cantonwine, DE1
Anzalota Del Toro, LV1
Calafat, AM1
Valentin-Blasini, L1
Davis, MD1
Baker, SE1
Alshawabkeh, AN1
Cordero, JF1
Meeker, JD1
MacFadden, DR1
Bogoch, II1
Wylie, BJ1
Hauptman, M1
Woolf, AD1
Goldman, RH1
Freedman, DO1
Koren, G1
Matsui, D1
Bailey, B1
Sudakin, DL1
Trevathan, WR1
Nevin, RD1
Snodgrass, HL1
Nelson, DC1
Weeks, MH1
Schoenig, GP1
Neeper-Bradley, TL1
Fisher, LC1
Hartnagel, RE1
Lindsay, SW2
Ewald, JA1
Samung, Y1
Apiwathnasorn, C1
Nosten, F2
Starr, M1
McGready, R1
Hamilton, KA1
Simpson, JA1
Cho, T1
Luxemburger, C1
Edwards, R1
Looareesuwan, S1
White, NJ1
Wright, DM1
Hardin, BD1
Goad, PW1
Chrislip, DW1
Schaefer, C1
Peters, PW1

Reviews

4 reviews available for deet and Pregnancy

ArticleYear
Challenges encountered by natural repellents: Since obtaining until the final product.
    Pesticide biochemistry and physiology, 2023, Volume: 195

    Topics: Aedes; Animals; DEET; Female; Humans; Insect Repellents; Mosquito Vectors; Oils, Volatile; Pregnancy

2023
[Recommendations for the use of insect repellents by pregnant women and children].
    Journal de pharmacie de Belgique, 2013, Issue:2

    Topics: Adult; Animals; Child; DEET; Dengue; Female; Humans; Insect Repellents; Insecta; Malaria; Pregnancy;

2013
Clinical practice. Malaria prevention in short-term travelers.
    The New England journal of medicine, 2008, Aug-07, Volume: 359, Issue:6

    Topics: Adult; Animals; Antimalarials; Child; DEET; Drug Resistance; Endemic Diseases; Female; Humans; Malar

2008
DEET: a review and update of safety and risk in the general population.
    Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:6

    Topics: Animals; Biotransformation; DEET; Drug Interactions; Female; Humans; Insect Repellents; Lactation; N

2003

Trials

1 trial available for deet and Pregnancy

ArticleYear
Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy.
    The American journal of tropical medicine and hygiene, 2001, Volume: 65, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Adult; Central Nervous System; Chromatography, High Pressure

2001

Other Studies

16 other studies available for deet and Pregnancy

ArticleYear
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Differentiation of action mechanisms between natural and synthetic repellents through neuronal electroantennogram and proteomic in Aedes aegypti (Diptera: Culicidae).
    Scientific reports, 2022, 11-27, Volume: 12, Issue:1

    Topics: Adult; Aedes; Animals; DEET; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Insect Repellent

2022
Epigenome-wide association study for pesticide (Permethrin and DEET) induced DNA methylation epimutation biomarkers for specific transgenerational disease.
    Environmental health : a global access science source, 2020, 11-04, Volume: 19, Issue:1

    Topics: Animals; Biomarkers; DEET; DNA Methylation; Epigenesis, Genetic; Epigenome; Female; Insect Repellent

2020
Urinary biomarkers of exposure to insecticides, herbicides, and one insect repellent among pregnant women in Puerto Rico.
    Environmental health : a global access science source, 2014, Nov-19, Volume: 13

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Adolescent; Adult; Biomarkers; DE

2014
Zika virus infection.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Mar-15, Volume: 188, Issue:5

    Topics: Aedes; Animals; Arthralgia; Conjunctivitis, Viral; DEET; Exanthema; Female; Guillain-Barre Syndrome;

2016
Insect Repellants During Pregnancy in the Era of the Zika Virus.
    Obstetrics and gynecology, 2016, Volume: 128, Issue:5

    Topics: Animals; Culicidae; DEET; Female; Humans; Insect Bites and Stings; Insect Repellents; Permethrin; Pr

2016
Preventing mosquito-borne infections.
    Prescrire international, 2008, Volume: 17, Issue:98

    Topics: Animals; Child; Culicidae; DEET; Disease Transmission, Infectious; Europe; Female; Humans; Infection

2008
DEET-based insect repellents: safety implications for children and pregnant and lactating women.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, Aug-05, Volume: 169, Issue:3

    Topics: Animals; Child; Culicidae; DEET; Female; Humans; Insect Bites and Stings; Insect Repellents; Pregnan

2003
Missing information on DEET.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004, Jan-06, Volume: 170, Issue:1

    Topics: Animals; Child; Culicidae; DEET; Female; Humans; Insect Bites and Stings; Insect Repellents; Pregnan

2004
Dermal penetration and potential for placental transfer of the insect repellent, N,N-diethyl-m-toluamide.
    American Industrial Hygiene Association journal, 1982, Volume: 43, Issue:10

    Topics: Absorption; Administration, Topical; Animals; Benzamides; DEET; Dogs; Female; Injections, Intravenou

1982
Teratologic evaluations of N,N-diethyl-m-toluamide (DEET) in rats and rabbits.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 23, Issue:1

    Topics: Animals; DEET; Embryonic and Fetal Development; Female; Fetal Resorption; Pregnancy; Rabbits; Rats;

1994
Thanaka (Limonia acidissima) and deet (di-methyl benzamide) mixture as a mosquito repellent for use by Karen women.
    Medical and veterinary entomology, 1998, Volume: 12, Issue:3

    Topics: Biological Assay; DEET; Ethnicity; Female; Humans; Insect Bites and Stings; Insect Repellents; Insec

1998
Malaria affects children and pregnant women most.
    BMJ (Clinical research ed.), 2000, Nov-18, Volume: 321, Issue:7271

    Topics: Antimalarials; Child; DEET; Doxycycline; Drug Combinations; Female; Humans; Insect Repellents; Malar

2000
Reproductive and developmental toxicity of N,N-diethyl-m-toluamide in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; DEET; Dose-Response Relationship, Drug; Embryonic and Fetal De

1992
Intrauterine diethyltoluamide exposure and fetal outcome.
    Reproductive toxicology (Elmsford, N.Y.), 1992, Volume: 6, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; DEET; Female; Fetus; Humans; Infant, Newborn; Male; Maternal-Fet

1992
Recommendations for the prevention of malaria in travelers.
    MMWR. Morbidity and mortality weekly report, 1988, May-06, Volume: 37, Issue:17

    Topics: Antimalarials; Breast Feeding; Child; Chloroquine; DEET; Drug Resistance; Female; Government Publica

1988
Leads from the MMWR. Recommendations for the prevention of malaria in travelers.
    JAMA, 1988, Jun-17, Volume: 259, Issue:23

    Topics: Antimalarials; Breast Feeding; Child; Chloroquine; DEET; Drug Resistance; Female; Government Publica

1988