deet has been researched along with Nervous System Disorders in 9 studies
N,N-diethyl-m-toluamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Risk of syndrome 2 ("confusion-ataxia") increased with a scale of advanced adverse effects from pyridostigmine bromide (chi2 for trend, P<." | 3.69 | Self-reported exposure to neurotoxic chemical combinations in the Gulf War. A cross-sectional epidemiologic study. ( Haley, RW; Kurt, TL, 1997) |
| "The DEET Registry is a post-marketing surveillance system to provide systematic and detailed information about medical events temporally associated with DEET use." | 1.36 | Adverse events associated with the use of insect repellents containing N,N-diethyl-m-toluamide (DEET). ( Fell, LA; Murphy, JV; Osimitz, TG; Page, B, 2010) |
| " An apparent treatment-related effect in thermal response time (increased) was noted for both sexes 1 hr after dosing at the 500 mg/kg dose level." | 1.29 | Neurotoxicity evaluation of N,N-diethyl-m-toluamide (DEET) in rats. ( Hartnagel, RE; Schardein, JL; Schoenig, GP; Vorhees, CV, 1993) |
| " We hypothesize that test compounds may compete for xenobiotic metabolizing enzymes in the liver and blood and may also compromise the integrity of the blood-brain barrier, leading to an increase in their "effective concentrations" in the nervous system to levels equivalent to the toxic doses of individual compounds." | 1.29 | Increased neurotoxicity following concurrent exposure to pyridostigmine bromide, DEET, and chlorpyrifos. ( Abdel-Rahman, AA; Abou-Donia, MB; Jensen, KF; Kurt, TL; Oehme, FW; Wilmarth, KR, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osimitz, TG | 1 |
| Murphy, JV | 1 |
| Fell, LA | 1 |
| Page, B | 1 |
| de Garbino, JP | 1 |
| Laborde, A | 1 |
| Schoenig, GP | 1 |
| Hartnagel, RE | 1 |
| Schardein, JL | 1 |
| Vorhees, CV | 1 |
| Pennisi, E | 1 |
| Abou-Donia, MB | 1 |
| Wilmarth, KR | 1 |
| Abdel-Rahman, AA | 1 |
| Jensen, KF | 1 |
| Oehme, FW | 1 |
| Kurt, TL | 2 |
| Haley, RW | 1 |
| Landrigan, PJ | 1 |
| Olson, CT | 1 |
| Blank, JA | 1 |
| Menton, RG | 1 |
| Verschoyle, RD | 1 |
| Brown, AW | 1 |
| Nolan, C | 1 |
| Ray, DE | 1 |
| Lister, T | 1 |
9 other studies available for deet and Nervous System Disorders
| Article | Year |
|---|---|
Adverse events associated with the use of insect repellents containing N,N-diethyl-m-toluamide (DEET).
Topics: Adolescent; Adult; Age Distribution; Child; Child, Preschool; Consumer Product Safety; DEET; Humans; | 2010 |
Toxicity of an insect repellent: N-N-diethyltoluamide.
Topics: Animals; Benzamides; Child; Child, Preschool; DEET; Drug Combinations; Female; Humans; Infant; Insec | 1983 |
Neurotoxicity evaluation of N,N-diethyl-m-toluamide (DEET) in rats.
Topics: Acoustic Stimulation; Animals; Avoidance Learning; Behavior, Animal; DEET; Drug Evaluation, Preclini | 1993 |
Chemicals behind Gulf War syndrome?
Topics: Animals; Chickens; DEET; Drug Interactions; Humans; Insect Repellents; Insecticides; Military Person | 1996 |
Increased neurotoxicity following concurrent exposure to pyridostigmine bromide, DEET, and chlorpyrifos.
Topics: Animals; Brain; Chickens; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterases; DEET; Drug Inter | 1996 |
Self-reported exposure to neurotoxic chemical combinations in the Gulf War. A cross-sectional epidemiologic study.
Topics: Adult; Ataxia; Carboxylic Ester Hydrolases; Chemical Warfare; Cholinesterase Inhibitors; Cognition D | 1997 |
Illness in Gulf War veterans. Causes and consequences.
Topics: Chemical Warfare; Cholinesterase Inhibitors; DEET; Environmental Exposure; Factor Analysis, Statisti | 1997 |
Neuromuscular effects of low level exposures to Sarin, pyridostigmine, DEET, and chlorpyrifos.
Topics: Animals; Behavior, Animal; Chlorpyrifos; DEET; Drug Interactions; Haplorhini; Nervous System Disease | 1998 |
A comparison of the acute toxicity, neuropathology, and electrophysiology of N,N-diethyl-m-toluamide and N,N-dimethyl-2,2-diphenylacetamide in rats.
Topics: Aging; Animals; Brain; DEET; Diphenylacetic Acids; Electrodes, Implanted; Electroencephalography; El | 1992 |