Page last updated: 2024-10-31

deet and Infections, Plasmodium

deet has been researched along with Infections, Plasmodium in 45 studies

N,N-diethyl-m-toluamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.

Research Excerpts

ExcerptRelevanceReference
"While there is strong evidence that bite protection methods such as permethrin-treated clothing and topical insect repellents are protective against insect bites, there are few studies assessing the impact on malaria infection."9.41Effect of interventions to reduce malaria incidence among military personnel on active duty: study protocol for a cluster randomised controlled trial of the impact of etofenprox-treated uniforms, permethrin-treated uniforms and DEET insect repellent. ( Hofer, L; Kohi, YM; Moore, SJ; Moshi, I; Msellemu, D; Mwanziva, C; Ross, A; Temu, L, 2021)
"DEET (diethyl-3-methylbenzamide), the widely used mosquito repellent, has the potential to prevent malarial infection but hitherto there has been no study demonstrating this possibility during normal everyday use."7.72DEET mosquito repellent sold through social marketing provides personal protection against malaria in an area of all-night mosquito biting and partial coverage of insecticide-treated nets: a case-control study of effectiveness. ( Downey, G; Freeman, T; Hadi, A; Rowland, M; Saeed, M, 2004)
" No adverse neurologic, gastrointestinal, or dermatologic effects were observed for women who applied a median total dose of 214."6.70Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy. ( Cho, T; Edwards, R; Hamilton, KA; Lindsay, SW; Looareesuwan, S; Luxemburger, C; McGready, R; Nosten, F; Simpson, JA; White, NJ, 2001)
"While there is strong evidence that bite protection methods such as permethrin-treated clothing and topical insect repellents are protective against insect bites, there are few studies assessing the impact on malaria infection."5.41Effect of interventions to reduce malaria incidence among military personnel on active duty: study protocol for a cluster randomised controlled trial of the impact of etofenprox-treated uniforms, permethrin-treated uniforms and DEET insect repellent. ( Hofer, L; Kohi, YM; Moore, SJ; Moshi, I; Msellemu, D; Mwanziva, C; Ross, A; Temu, L, 2021)
"DEET MC is a formulation of DEET (N,N diethyl-m-toluamide) in which the repellent is gradually released from a capsule that binds the repellent."5.35DEET microencapsulation: a slow-release formulation enhancing the residual efficacy of bed nets against malaria vectors. ( Knols, BG; N'guessan, R; Pennetier, C; Rowland, M, 2008)
"Deet ED50 values were 2."5.28Deet and permethrin as protectants against malaria-infected and uninfected Anopheles stephensi mosquitoes. ( Robert, LL; Schneider, I; Wirtz, RA, 1991)
"574 g quwenling (p-menthane-3,8-diol, PMD) and the standard deet (15% diethyl-3-methylbenzamide, Tabard lotion), were compared against a laboratory colony of the mosquito Anopheles arabiensis Patton (Diptera: Culicidae), the predominant malaria vector in South Africa."5.09Efficacy of three insect repellents against the malaria vector Anopheles arabiensis. ( Baker, L; Coetzee, M; Durrheim, DN; Govere, J; Hunt, R, 2000)
" The crude mixture of isomers obtained in the reaction was tested under laboratory conditions for its repellency against two mosquito species, the major malaria vector Anopheles gambiae and the arbovirus vector Aedes albopictus, and found to be endowed with longer protection time with respect to DEET (N,N-diethyl-meta-toluamide) at the same concentration."4.12Advances in mosquito repellents: effectiveness of citronellal derivatives in laboratory and field trials. ( Caputo, B; Cobre, P; Dani, FR; Iovinella, I; Mandoli, A; Manica, M, 2022)
"Contact irritant and non-contact repellent activities of β-caryophyllene oxide were evaluated against laboratory strains of female Aedes aegypti (USDA strain), a major arbovirus vector and Anopheles minimus (KU strain), a major malaria parasite vector, compared with the synthetic repellent DEET, using an excito-repellency test system."3.91Excito-repellent activity of β-caryophyllene oxide against Aedes aegypti and Anopheles minimus. ( Chareonviriyaphap, T; Kongmee, M; Mahiou-Leddet, V; Manguin, S; Nararak, J; Ollivier, E; Sathantriphop, S, 2019)
"DEET (diethyl-3-methylbenzamide), the widely used mosquito repellent, has the potential to prevent malarial infection but hitherto there has been no study demonstrating this possibility during normal everyday use."3.72DEET mosquito repellent sold through social marketing provides personal protection against malaria in an area of all-night mosquito biting and partial coverage of insecticide-treated nets: a case-control study of effectiveness. ( Downey, G; Freeman, T; Hadi, A; Rowland, M; Saeed, M, 2004)
" No adverse neurologic, gastrointestinal, or dermatologic effects were observed for women who applied a median total dose of 214."2.70Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy. ( Cho, T; Edwards, R; Hamilton, KA; Lindsay, SW; Looareesuwan, S; Luxemburger, C; McGready, R; Nosten, F; Simpson, JA; White, NJ, 2001)
"Malaria is a vector-borne disease that causes many deaths worldwide; repellents are a practical approach to malaria prevention, especially in endemic regions."1.91Repellent efficacy of the nanogel containing Acroptilon repens essential oil in comparison with DEET against Anopheles stephensi. ( Babaalizadeh, B; Osanloo, M; Qasmei, H; Sanei-Dehkordi, A; Zarenezhad, E, 2023)
"DEET MC is a formulation of DEET (N,N diethyl-m-toluamide) in which the repellent is gradually released from a capsule that binds the repellent."1.35DEET microencapsulation: a slow-release formulation enhancing the residual efficacy of bed nets against malaria vectors. ( Knols, BG; N'guessan, R; Pennetier, C; Rowland, M, 2008)
"Deet ED50 values were 2."1.28Deet and permethrin as protectants against malaria-infected and uninfected Anopheles stephensi mosquitoes. ( Robert, LL; Schneider, I; Wirtz, RA, 1991)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19906 (13.33)18.7374
1990's4 (8.89)18.2507
2000's19 (42.22)29.6817
2010's11 (24.44)24.3611
2020's5 (11.11)2.80

Authors

AuthorsStudies
Msellemu, D1
Ross, A1
Temu, L1
Moshi, I1
Hofer, L1
Mwanziva, C1
Kohi, YM1
Moore, SJ5
Iovinella, I1
Caputo, B1
Cobre, P1
Manica, M1
Mandoli, A1
Dani, FR1
Akeumbiwo Tchumkam, C1
Kojom Foko, LP1
Ndo, C1
Essangui Same, E1
Cheteug Nguetsa, G1
Eya'Ane Meva, F1
Ayong, L1
Eboumbou Moukoko, CE1
Zarenezhad, E1
Sanei-Dehkordi, A1
Babaalizadeh, B1
Qasmei, H1
Osanloo, M1
Traoré, A1
Niyondiko, G1
Sanou, A1
Langevin, F1
Sagnon, N1
Gansané, A1
Guelbeogo, MW1
Deletre, E1
Martin, T1
Duménil, C1
Chandre, F2
Nararak, J1
Sathantriphop, S1
Kongmee, M1
Mahiou-Leddet, V1
Ollivier, E1
Manguin, S1
Chareonviriyaphap, T1
Leuckx, S1
Chen-Hussey, V2
Carneiro, I1
Keomanila, H1
Gray, R1
Bannavong, S1
Phanalasy, S1
Lindsay, SW2
Miszta, P1
Basak, SC1
Natarajan, R1
Nowak, W1
Sangoro, O1
Turner, E1
Simfukwe, E1
Miller, JE1
Stanczyk, NM1
Behrens, RH1
Stewart, SA1
Logan, JG1
Abiy, E1
Gebre-Michael, T1
Balkew, M1
Medhin, G1
Freedman, DO1
Pennetier, C2
Costantini, C2
Corbel, V1
Licciardi, S1
Dabiré, RK1
Lapied, B1
Hougard, JM1
Khoobdel, M1
Jonaidi, N1
Sorge, F1
Lee, VJ1
Ow, S1
Heah, H1
Tan, MY1
Lam, P1
Ng, LC1
Lam-Phua, SG1
Imran, AQ1
Seet, B1
Liu, C1
Pitts, RJ1
Bohbot, JD1
Jones, PL1
Wang, G1
Zwiebel, LJ1
Dube, FF1
Tadesse, K1
Birgersson, G1
Seyoum, E1
Tekie, H1
Ignell, R1
Hill, SR1
Rysstad, O1
Skjeie, H1
Bannister, B2
Bradley, DJ1
Rowland, M2
Freeman, T1
Downey, G1
Hadi, A1
Saeed, M1
Badolo, A1
Ilboudo-Sanogo, E1
Ntonifor, NN1
Ngufor, CA1
Kimbi, HK1
Oben, BO1
Davies, CR1
Hill, N2
Cameron, MM1
Darling, ST1
Sihuincha, M1
Padilla, N1
Devine, GJ1
N'guessan, R1
Knols, BG1
Copeland, RS1
Walker, TW1
Robert, LL2
Githure, JI1
Wirtz, RA2
Klein, TA1
Starr, M1
Govere, J1
Durrheim, DN2
Baker, L1
Hunt, R1
Coetzee, M1
McGready, R1
Hamilton, KA1
Simpson, JA1
Cho, T1
Luxemburger, C1
Edwards, R1
Looareesuwan, S1
White, NJ1
Nosten, F1
Govere, JM1
Lenglet, A1
Schneider, I1
Chiang, GL1
Tay, SL1
Eng, KL1
Chan, ST1
Nettleman, MD1
Charlwood, JD1
Dagoro, H1
Schreck, CE1
DeWitt, DE1
Ostergaard, D1
Grothaus, RH1
Adams, JF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents To Reduce Malaria Incidence In Military Personnel On Active Duty In Regions Of Hyperendemicity[NCT02938975]Phase 31,500 participants (Anticipated)Interventional2017-11-30Not yet recruiting
Clinical Evaluation of Insect Repellent and Insecticide Treated Nets Against Malaria, JE & Dengue in Rural Communities in Lao PDR[NCT00938379]Phase 35,000 participants (Anticipated)Interventional2009-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for deet and Infections, Plasmodium

ArticleYear
[Recommendations for the use of insect repellents by pregnant women and children].
    Journal de pharmacie de Belgique, 2013, Issue:2

    Topics: Adult; Animals; Child; DEET; Dengue; Female; Humans; Insect Repellents; Insecta; Malaria; Pregnancy;

2013
Clinical practice. Malaria prevention in short-term travelers.
    The New England journal of medicine, 2008, Aug-07, Volume: 359, Issue:6

    Topics: Adult; Animals; Antimalarials; Child; DEET; Drug Resistance; Endemic Diseases; Female; Humans; Malar

2008
Emporiatrics: protecting travelers from malaria.
    Infection control and hospital epidemiology, 1990, Volume: 11, Issue:7

    Topics: Adult; Antimalarials; Child; DEET; Humans; Malaria; Mosquito Control; Travel

1990

Trials

5 trials available for deet and Infections, Plasmodium

ArticleYear
Effect of interventions to reduce malaria incidence among military personnel on active duty: study protocol for a cluster randomised controlled trial of the impact of etofenprox-treated uniforms, permethrin-treated uniforms and DEET insect repellent.
    Trials, 2021, Nov-21, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Clothing; DEET; Humans; Incidence; Insect Repellents; Insecticides; Malaria; Mili

2021
Can topical insect repellents reduce malaria? A cluster-randomised controlled trial of the insect repellent N,N-diethyl-m-toluamide (DEET) in Lao PDR.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Animals; Child; Culicidae; DEET; Female; Humans; Insect

2013
A cluster-randomized controlled trial to assess the effectiveness of using 15% DEET topical repellent with long-lasting insecticidal nets (LLINs) compared to a placebo lotion on malaria transmission.
    Malaria journal, 2014, Aug-16, Volume: 13

    Topics: Adolescent; Adult; Child; Child, Preschool; Cluster Analysis; DEET; Female; Humans; Infant; Infant,

2014
Efficacy of three insect repellents against the malaria vector Anopheles arabiensis.
    Medical and veterinary entomology, 2000, Volume: 14, Issue:4

    Topics: Adult; Animals; Anopheles; Cross-Over Studies; DEET; Female; Forearm; Humans; Insect Bites and Sting

2000
Safety of the insect repellent N,N-diethyl-M-toluamide (DEET) in pregnancy.
    The American journal of tropical medicine and hygiene, 2001, Volume: 65, Issue:4

    Topics: Administration, Cutaneous; Adolescent; Adult; Central Nervous System; Chromatography, High Pressure

2001

Other Studies

37 other studies available for deet and Infections, Plasmodium

ArticleYear
Advances in mosquito repellents: effectiveness of citronellal derivatives in laboratory and field trials.
    Pest management science, 2022, Volume: 78, Issue:12

    Topics: Aedes; Animals; Anopheles; DEET; Humans; Insect Repellents; Malaria; Mosquito Vectors

2022
Chemical composition and repellent activity of essential oils of Tithonia diversifolia (Asteraceae) leaves against the bites of Anopheles coluzzii.
    Scientific reports, 2023, 04-12, Volume: 13, Issue:1

    Topics: Animals; Anopheles; Asteraceae; DEET; Gas Chromatography-Mass Spectrometry; Humans; Insect Repellent

2023
Repellent efficacy of the nanogel containing Acroptilon repens essential oil in comparison with DEET against Anopheles stephensi.
    BMC research notes, 2023, Oct-09, Volume: 16, Issue:1

    Topics: Animals; Anopheles; DEET; Humans; Insect Repellents; Malaria; Mosquito Vectors; Nanogels; Oils, Vola

2023
Laboratory and field evaluation of MAÏA
    Malaria journal, 2021, May-20, Volume: 20, Issue:1

    Topics: Adult; Aedes; Animals; Anopheles; Burkina Faso; DEET; Female; Humans; Insect Repellents; Malaria; Ma

2021
Insecticide resistance modifies mosquito response to DEET and natural repellents.
    Parasites & vectors, 2019, Mar-12, Volume: 12, Issue:1

    Topics: Acrolein; Acyclic Monoterpenes; Animals; Anopheles; Cymenes; DEET; Female; Humans; Insect Repellents

2019
Excito-repellent activity of β-caryophyllene oxide against Aedes aegypti and Anopheles minimus.
    Acta tropica, 2019, Volume: 197

    Topics: Aedes; Animals; Anopheles; Arbovirus Infections; DEET; Female; Insect Repellents; Malaria; Mosquito

2019
How computational studies of mosquito repellents contribute to the control of vector Borne Diseases.
    Current computer-aided drug design, 2013, Volume: 9, Issue:3

    Topics: Animals; Anopheles; Antimalarials; Computer-Aided Design; DEET; Drug Discovery; Humans; Insect Prote

2013
Mosquito repellents for travellers.
    BMJ (Clinical research ed.), 2015, Feb-19, Volume: 350

    Topics: Animals; Culicidae; Cyclohexane Monoterpenes; DEET; Humans; Insect Bites and Stings; Insect Repellen

2015
Repellent efficacy of DEET, MyggA, neem (Azedirachta indica) oil and chinaberry (Melia azedarach) oil against Anopheles arabiensis, the principal malaria vector in Ethiopia.
    Malaria journal, 2015, May-03, Volume: 14

    Topics: Adult; Animals; Anopheles; Child; DEET; Ethiopia; Glycerides; Humans; Insect Repellents; Insect Vect

2015
Mixture for controlling insecticide-resistant malaria vectors.
    Emerging infectious diseases, 2008, Volume: 14, Issue:11

    Topics: Acetylcholinesterase; Alleles; Animals; Anopheles; Burkina Faso; Cholinesterase Inhibitors; DEET; Fe

2008
Laboratory determination of protection time in four chemical repellents against Anopheles stephensi.
    Pakistan journal of biological sciences : PJBS, 2007, Aug-15, Volume: 10, Issue:16

    Topics: Animals; Anopheles; DEET; Female; Humans; Insect Repellents; Iran; Malaria; Time Factors

2007
Preventing mosquito-borne infections.
    Prescrire international, 2008, Volume: 17, Issue:98

    Topics: Animals; Child; Culicidae; DEET; Disease Transmission, Infectious; Europe; Female; Humans; Infection

2008
[Prevention with repellent in children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2009, Volume: 16 Suppl 2

    Topics: Animals; Arthropod Vectors; Child; DEET; Drug Tolerance; France; Humans; Insect Repellents; Malaria;

2009
Elimination of malaria risk through integrated combination strategies in a tropical military training island.
    The American journal of tropical medicine and hygiene, 2010, Volume: 82, Issue:6

    Topics: Animals; Anopheles; Antimalarials; Bacillus thuringiensis; DEET; Geography; Humans; Insect Repellent

2010
Distinct olfactory signaling mechanisms in the malaria vector mosquito Anopheles gambiae.
    PLoS biology, 2010, Aug-31, Volume: 8, Issue:8

    Topics: Animals; Anopheles; Behavior, Animal; DEET; Gene Silencing; Insect Repellents; Insect Vectors; Larva

2010
Fresh, dried or smoked? Repellent properties of volatiles emitted from ethnomedicinal plant leaves against malaria and yellow fever vectors in Ethiopia.
    Malaria journal, 2011, Dec-19, Volume: 10

    Topics: Acyclic Monoterpenes; Aedes; Alkenes; Animals; Anopheles; Behavior, Animal; Biological Assay; DEET;

2011
[Different advice about non-medical malaria prophylaxis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, Jan-09, Volume: 123, Issue:1

    Topics: Antimalarials; DEET; Humans; Insect Repellents; Malaria; Travel

2003
Malaria 2003: the malaria parasite is still evolving, but so are the options for prophylaxis.
    Communicable disease and public health, 2003, Volume: 6, Issue:3

    Topics: Antimalarials; DEET; Humans; Malaria; Protective Clothing; Travel; United Kingdom

2003
Guidelines for malaria prevention in travellers from the United Kingdom for 2003.
    Communicable disease and public health, 2003, Volume: 6, Issue:3

    Topics: Adult; Animals; Antimalarials; Bedding and Linens; Child; Culicidae; DEET; Female; Half-Life; Humans

2003
DEET mosquito repellent sold through social marketing provides personal protection against malaria in an area of all-night mosquito biting and partial coverage of insecticide-treated nets: a case-control study of effectiveness.
    Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:3

    Topics: Adolescent; Afghanistan; Age Distribution; Analysis of Variance; Animals; Anopheles; Bedding and Lin

2004
Field evaluation of the efficacy and persistence of insect repellents DEET, IR3535, and KBR 3023 against Anopheles gambiae complex and other Afrotropical vector mosquitoes.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2004, Volume: 98, Issue:11

    Topics: Administration, Topical; Adult; Aedes; Animals; Anopheles; Burkina Faso; DEET; Dose-Response Relatio

2004
Traditional use of indigenous mosquito-repellents to protect humans against mosquitoes and other insect bites in a rural community of Cameroon.
    East African medical journal, 2006, Volume: 83, Issue:10

    Topics: Adult; Animals; Anopheles; Bedding and Linens; Cameroon; DEET; Health Knowledge, Attitudes, Practice

2006
Are mosquitoes diverted from repellent-using individuals to non-users? Results of a field study in Bolivia.
    Tropical medicine & international health : TM & IH, 2007, Volume: 12, Issue:4

    Topics: Animals; Anopheles; Bolivia; Cymbopogon; DEET; Feeding Behavior; Humans; Insect Bites and Stings; In

2007
A low-cost repellent for malaria vectors in the Americas: results of two field trials in Guatemala and Peru.
    Malaria journal, 2007, Aug-01, Volume: 6

    Topics: Animals; Anopheles; Cyclohexane Monoterpenes; DEET; Eucalyptus; Guatemala; Humans; Insect Bites and

2007
DEET microencapsulation: a slow-release formulation enhancing the residual efficacy of bed nets against malaria vectors.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2008, Volume: 102, Issue:3

    Topics: Animals; Anopheles; Bedding and Linens; Culex; DEET; Drug Compounding; Humans; Insect Bites and Stin

2008
Response of wild Anopheles funestus to repellent-protected volunteers is unaffected by malaria infection of the vector.
    Journal of the American Mosquito Control Association, 1995, Volume: 11, Issue:4

    Topics: Animals; Anopheles; DEET; Feeding Behavior; Female; Host-Parasite Interactions; Humans; Insect Repel

1995
Malaria affects children and pregnant women most.
    BMJ (Clinical research ed.), 2000, Nov-18, Volume: 321, Issue:7271

    Topics: Antimalarials; Child; DEET; Doxycycline; Drug Combinations; Female; Humans; Insect Repellents; Malar

2000
Malaria outbreak control in an African village by community application of 'deet' mosquito repellent to ankles and feet.
    Medical and veterinary entomology, 2002, Volume: 16, Issue:1

    Topics: Animals; Anopheles; Bites and Stings; DEET; Disease Outbreaks; Feeding Behavior; Foot; Humans; Insec

2002
Field evaluation of three plant-based insect repellents against malaria vectors in Vaca Diez Province, the Bolivian Amazon.
    Journal of the American Mosquito Control Association, 2002, Volume: 18, Issue:2

    Topics: Animals; Anopheles; Bolivia; Cyclohexane Monoterpenes; DEET; Eucalyptus; Glycerides; Humans; Insect

2002
Deet and permethrin as protectants against malaria-infected and uninfected Anopheles stephensi mosquitoes.
    Journal of the American Mosquito Control Association, 1991, Volume: 7, Issue:2

    Topics: Animals; Anopheles; DEET; Dose-Response Relationship, Drug; Insect Bites and Stings; Insect Repellen

1991
Effectiveness of repellent/insecticidal bars against malaria and filariasis vectors in peninsular Malaysia.
    The Southeast Asian journal of tropical medicine and public health, 1990, Volume: 21, Issue:3

    Topics: Animals; Culicidae; DEET; Filariasis; Humans; Insect Repellents; Insect Vectors; Insecticides; Malar

1990
Repellent soap for use against malaria vectors in Papua New Guinea.
    Papua and New Guinea medical journal, 1987, Volume: 30, Issue:4

    Topics: Animals; Benzamides; Culicidae; DEET; Humans; Insect Repellents; Malaria; Papua New Guinea; Permethr

1987
Recommendations for the prevention of malaria in travelers.
    MMWR. Morbidity and mortality weekly report, 1988, May-06, Volume: 37, Issue:17

    Topics: Antimalarials; Breast Feeding; Child; Chloroquine; DEET; Drug Resistance; Female; Government Publica

1988
Leads from the MMWR. Recommendations for the prevention of malaria in travelers.
    JAMA, 1988, Jun-17, Volume: 259, Issue:23

    Topics: Antimalarials; Breast Feeding; Child; Chloroquine; DEET; Drug Resistance; Female; Government Publica

1988
The status of deet (N,N-diethyl-m-toluamide) as a repellent for Anopheles albimanus.
    Journal of the American Mosquito Control Association, 1985, Volume: 1, Issue:1

    Topics: Administration, Cutaneous; Animals; Anopheles; Benzamides; DEET; Female; Humans; Insect Bites and St

1985
Malaria. Prevention is the key.
    Postgraduate medicine, 1985, Volume: 77, Issue:1

    Topics: Clothing; DEET; Humans; Malaria; Travel

1985
An innovation in mosquito-borne disease protection.
    Military medicine, 1972, Volume: 137, Issue:5

    Topics: Benzoates; Culicidae; DEET; Humans; Insect Repellents; Malaria; Military Medicine; Mosquito Control;

1972