decanoic acid has been researched along with Aura in 5 studies
decanoate : A fatty acid anion 10:0 that is the conjugate base of decanoic acid.
decanoic acid : A C10, straight-chain saturated fatty acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Decanoic acid, a component of medium-chain triclycerides, contributes to seizure control through direct α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor inhibition, whereas drugs targeting lactate dehydrogenase reduce seizures through inhibition of a metabolic pathway." | 4.95 | New insights into the mechanisms of the ketogenic diet. ( Boison, D, 2017) |
| "Perampanel (PER) is a non-competitive AMPAR antagonist, and pre-clinical studies have shown the AMPAR-mediated anticonvulsant effects of decanoic acid (DEC), a major medium-chain fatty acid provided in the medium-chain triglyceride ketogenic diet." | 1.56 | Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition. ( Agrawal, S; Greenhill, SD; Lo, WB; Mundil, N; Philip, S; Seri, S; Walsh, R; Wilson, MA; Woodhall, GL; Wright, SK, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shekhar, N | 1 |
| Tyagi, S | 1 |
| Rani, S | 1 |
| Thakur, AK | 1 |
| Wright, SK | 1 |
| Wilson, MA | 1 |
| Walsh, R | 1 |
| Lo, WB | 1 |
| Mundil, N | 1 |
| Agrawal, S | 1 |
| Philip, S | 1 |
| Seri, S | 1 |
| Greenhill, SD | 1 |
| Woodhall, GL | 1 |
| Warren, EC | 1 |
| Dooves, S | 1 |
| Lugarà, E | 1 |
| Damstra-Oddy, J | 1 |
| Schaf, J | 1 |
| Heine, VM | 1 |
| Walker, MC | 1 |
| Williams, RSB | 1 |
| Enderlin, J | 1 |
| Loussouarn, A | 1 |
| Benoist, JF | 1 |
| Dozières-Puyravel, B | 1 |
| Auvin, S | 1 |
| Boison, D | 1 |
2 reviews available for decanoic acid and Aura
| Article | Year |
|---|---|
Potential of Capric Acid in Neurological Disorders: An Overview.
Topics: Animals; Decanoic Acids; Diet, Ketogenic; Epilepsy; Fatty Acids; Humans; Mammals | 2023 |
New insights into the mechanisms of the ketogenic diet.
Topics: Anticonvulsants; Decanoic Acids; Diet, Ketogenic; Epilepsy; Humans; Seizures | 2017 |
3 other studies available for decanoic acid and Aura
| Article | Year |
|---|---|
Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition.
Topics: Adolescent; Anticonvulsants; Brain; Child; Child, Preschool; Decanoic Acids; Drug Resistant Epilepsy | 2020 |
Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Astrocytes; Cell Cycle Proteins; Cells, Cultured; Dec | 2020 |
Absence of increased blood decanoic acid levels in children with epilepsy treated with classic ketogenic diet.
Topics: Adolescent; Anticonvulsants; Child; Decanoic Acids; Diet, Ketogenic; Epilepsy; Female; Humans; Male; | 2019 |