decamethonium has been researched along with Parkinson Disease in 1 studies
decamethonium: RN given refers to parent cpd
decamethonium : A quaternary ammonium ion that is a depolarising muscle relaxant whose structure comprises a decane-1,10-diamine core in which each amino group carries three methyl substituents.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "alpha-Synuclein is the major constituent of Lewy bodies, a pathological signature of Parkinson disease, found in the degenerating dopaminergic neurons of the substantia nigra pars compacta." | 3.73 | Dequalinium-induced protofibril formation of alpha-synuclein. ( Cho, HJ; Chung, KC; Jung, S; Kim, HJ; Kim, J; Lee, CH; Lee, JH; Paik, SR, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, CH | 1 |
| Kim, HJ | 1 |
| Lee, JH | 1 |
| Cho, HJ | 1 |
| Kim, J | 1 |
| Chung, KC | 1 |
| Jung, S | 1 |
| Paik, SR | 1 |
1 other study available for decamethonium and Parkinson Disease
| Article | Year |
|---|---|
Dequalinium-induced protofibril formation of alpha-synuclein.
Topics: alpha-Synuclein; Amyloid; Anti-Infective Agents, Local; Binding Sites; Cations; Cell Death; Cell Lin | 2006 |